The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Simponi (golimumab) for Ankylosing Spondylitis: I have had severe and debilitating whole back/shoulder/neck pain since I was 17 - I'm now 27 and have always been very active. I was given Vimovo, which did not help all that much; and although Ibuprofen did help more (though not entirely), it was more dangerous for long-term use.
I had a false positive for the TB skin test - if this happens to you, ask for the TB Quanteferon test - it was $90 out of pocket, but came back with a 100% negative test result and I was able to take my first injection within that week - it's sad because I had the false positive in Oct 2013 and had to wait until mid-Feb 2014 to start on Simponi.
Simponi itself is wonderful. Within hours, I felt no pain at all and had no side-effects. I can put on socks again!
Simponi (golimumab) for Psoriatic Arthritis: I took Simponi for 8 months before stopping to get pregnant with my son. All of my symptoms had disappeared and I was 100% flare up free.
However, after having my little guy and starting the Simponi injections again I have not had any relief to my psoriasis and have experienced 2 flare ups even after upping my dose to every 3 weeks. How can it have worked so well and now not well at all. I have requested an appointment with my rheumatologist to discuss other biologic medicines.
Simponi (golimumab) for Rheumatoid Arthritis: I was also hit hard with rheumatoid arthritis in 2011. Tried prednisone, followed by methotrexate pills, Arava and others, nothing helped. In 2012 I was put on Humira which helped a lot for a few months, but not enough. Since January 2013 I use Simponi along with 0.8 ml methotrexate injections, and it has given me back my quality of life.
After 1 1/2 years I could bend my pinky finger again, wow! For me the change was subtle, but very effective. I tried alternative meds etc. after being diagnosed and didn't want to take this route, but honestly I cannot live without it. For me it works, it's a miracle.
Simponi (golimumab) for Ankylosing Spondylitis: Simponi helps me so much.
I take 2 shots per month.
I Washington diagnosed about 7 or 8 years after mycket first signs of illness. Ive had it very hard.
I get oxycontin when i have it too hard. But all in all, simponi is The best. I got a new life with it.
Works as a chef, and without simponi i would not.
I live in sweden, so i only pay about $300 a year.
Or else i would have to pay ALOT. like $4000 per month.
The negatives with this med, you cancer get alot of crap from it.
But the pain i had before was crazy.
Thank you my sweet Dr.
Simponi (golimumab) for Rheumatoid Arthritis: I was hit hard with rheumatoid arthritis in March 2012 and practically disabled by May. I couldn't tolerate methotrexate or Enbrel due to reactions. I started Simponi in October with 20mg Arava. It has given me my life back! I literally don't hurt at all most days! After nine months, I did develop a bad case of Palmer Planter Psoriasis as a side effect. Yet, I still want Simponi! That's how much it's improved my quality if life. The pens are easy to use and don't hurt compared to Enbrel. I've had no other reactions besides a shaky feeling on first month only.
Simponi (golimumab) for Rheumatoid Arthritis: I have been taking Simponi Injections for over a year now. It works better than Humira. I also take Methotrexate which has my hair coming out. I was taking 4pills every week, now I'm taking 3 pills every week. I'm 39 years old and my hair is coming out even when I just have it braided. I love the Simponi. I know when it's time to take it again though.
Simponi (golimumab) for Psoriatic Arthritis: I had been taking methotrexate for almost a year with moderate results. My skin cleared almost 80%, and my joints improved approximately 60%, however each time I took my medication I felt really ill for 48 hours afterwards. It was depressing. Anyway my Rheumatologist recommended Simponi. Having read the side effects, etc. I was a little apprehensive about taking Simponi, but after meeting with the Simponi nurse I decided to go with it. After two shots (2 months) I felt a big difference, my joints were no longer stiff and I was almost pain free. After the fourth shot my skin has cleared to 95% and I have no stiffness in my joints. It really is working for me.
16 users found this comment helpful.
Simponi (golimumab) for Ankylosing Spondylitis: Simponi has helped my symptoms tremendously. I did not have to take methotrexate along with this. I am very happy to be almost pain free. But I do notice maybe psoriasis beginning on my scalp.
Review by edmohring (taken for 6 months to 1 year):
Simponi (golimumab) for Rheumatoid Arthritis: Have been on Simponi for 6 months. Works great, and within 1-2 days. Was on methotrexate for many months and it did nothing. Then tried Humira for 1 month which worked well. Rheumatologist then switched me to Simponi. Monthly injection is much better than every two weeks (Humira). Unfortunately my insurance, Health Spring, refuses to cover it. Dr. has been giving me free samples of Simponi.
10 users found this comment helpful.
Simponi (golimumab) for Ankylosing Spondylitis: I have narcolepsy and ankylosing spondylitis, I also suspect that I have Psoriasis on my scalp, but haven't had it diagnosed officially yet. Simponi relieves some of the pain and discomfort from the AS and I usually have no lesions on my scalp while I am using the injection regularly. I also take 5 tabs of methotrexate weekly (along with all the side medication that goes along with these). I recently came down with a bad cold and was taken off these medicines temporarily. Immediately upon missing my injection my symptoms were back. The lesions started to appear on my scalp and are pretty bad. I would say that my quality of life has significantly improved since starting the Simponi about a year and a half ago. I take one injections per month.
Simponi (golimumab) for Ankylosing Spondylitis: I have been diagnosed with Ankylosing Spondylitis now for the last five years. I'm now 40 years old and it started to hit me quite hard after the age of 18 and started treatment on Humira at 35 first. Slack medical advice and thinking that I was fully cured, I stopped my treatment within 3 months my AS came back very strong as I was now working out 5 days a week in the gym. In Autstralia if you don't keep blood checks and things within certain times they strike you from the assistance hence my specialist has now put me on Simponi and all I can say is WOW. This stuff works and works well. I did notice very small signs of AS in the 4 weeks, which disappeared on the next injection. I found I had been given a new chance to live a normal life.
15 users found this comment helpful.
Simponi (golimumab) for Psoriatic Arthritis: I was almost wheelchair bound, every joint in my body inflamed and lots of pain walking. Psoriasis was flaring too all over.
The day I took my first shot I could feel the joints loosening and pain lessening. Within 6 months I was virtually pain free and completely mobile. 2 years now and I am riding my bike 25 miles a day and combined with light treatment my skin is 90% clear.
32 users found this comment helpful.
Simponi (golimumab) for Ankylosing Spondylitis: Was diagnosed with osteoporosis in 2000 and ankylosing spondylitis in 2003. I have been put on different medications for both. I have been on Simponi for about 6 months and have not noticed any improvement. It is easy to use but that is about all.
Simponi (golimumab) for Rheumatoid Arthritis: I am 3 weeks into my second dose of Simponi. Was on Enbrel for 4 1/2 yrs. with good results then it stopped working. the numerous side effects following my first dose came close to keeping me from trying a second month. this month i have had diarrhea for 3 weeks but that's an improvement over last month. joint pain, stiffness are better; but no effect on fatigue so far. It takes 6-8 weeks to know for sure how it will work. It is not possible to see results in hours or days. I have decided to try one more month since my next step is infusion mediciness.
25 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: Simponi felt like it was working the first 2 months. But my flare ups are still monthly and today after 6 months, my doctor said I am getting worse, and is taking me off Simponi. I am 53, have rheumatoid arthritis since 2007.
20 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: I have been on Simponi since 11/09. Took a couple of months to kick-in, and seems to wear off about the 3 1/2 weeks. Best results I have ever had. Did not use with Methotrexate due to had neuropathy symptoms when I take Methotrexate. I have had rheumatoid arthritis for 18 years and I am 55 years old, been on every RA medicine, Simponi is the best for me.
54 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: I started Simponi in April and have now had four injections. It worked the first night, my shoulder pain was gone and I have slept without pain since. I have had no reactions whatsoever. The drug has lasted the full month every time. In the month previous to my first injection I took 150 Tylenol 3's for the pain. In the 3 months since I have averaged 30 per month. My shoulders, wrists, hands, and knees are almost pain free with very little stiffness. I still can't work but at least I have my life back, thanks to Simponi. Methotrexate was too hard on my kidneys but I still take 20mg Arava every other day and Plaquenil and Diclofenac daily. I also take Ramipril for the raised blood pressure the drugs have caused.
29 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: I started taking Simponi 4 days ago after a very severe flare-up. I am 54 years old and have had rheumatoid arthritis for 29 years. I was pretty much incapacitated with the pain. Two days ago I was able to resume my normal household chores and feel so much better! I really hope the effectiveness continues.
33 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: I have had two doses. My doctor (and myself and my family) are very happy with the progress thus far. I am a 38 year old mother of three and am so thankful for this medication. My doctor hopes to start weaning me off methotrexate in the next few months. I applied for the patient care plan and have had no problems with it. I picked up my first dose last month at the pharmacy without any glitches. Almost all swelling and pain is gone. I noticed that it fades a bit the last week before my next dose. We'll see how it goes this month. Still, leaps and bounds better than taking three different kinds of medicines! Thank you Simponi.
35 users found this comment helpful.
Simponi (golimumab) for Rheumatoid Arthritis: I have been on Simponi for 4 months now. Just took my 4th dose. I love it. It just plain works. No swelling at all now. I work daily, on my feet, with my hands, bending, lifting etc. Pain free is the way to be. I switched from Humira to Simponi. Humira worked well, but had some minor side effects.
The Humira "pen" just plain hurts. So I used the prefilled syringes of Humira.
The Simponi "pen" works great!! Painless, fast and easier to use. It allows you to hold it in your fist and squeeze to activate. It is a light squeeze, so no difficulty in using it. At least for me.
It took a couple days to notice any effects, but all were positive.
Doctor visits have been very good....
48 users found this comment helpful.
Simponi (golimumab) for Ankylosing Spondylitis: Works good and helps mobility. you can feel it working in 2-3 days. Also the injection process is quick and pain free. Thanks for the second chance at a bearable life.
36 users found this comment helpful.
Simponi (golimumab) for Psoriatic Arthritis: I've been using Simponi for Psoriatic Arthritis for 5 months. Before that I was using Enbrel. I had a small amount of psoriasis on my scalp before starting Simponi and now I have much more. I like the once a month injection but believe I'll be returning to Enbrel soon as I believe it did a better job.
24 users found this comment helpful.
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