Golimumab Dosage

This dosage information may not include all the information needed to use Golimumab safely and effectively. See additional information for Golimumab.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Ankylosing Spondylitis

50 mg administered by subcutaneous (SC) injection once a month

Comments:
-Psoriatic arthritis (PsA) or ankylosing spondylitis (AS): May be given with or without methotrexate or other non-biologic Disease Modifying Antirheumatic Drugs (DMARDs).
-PsA or AS: Corticosteroids, non-biologic DMARDs, and/or NSAIDs may be continued during golimumab treatment.

Approved indications for this dose:
-Active psoriatic arthritis alone or in combination with methotrexate
-Active ankylosing spondylitis

Usual Adult Dose for Psoriatic Arthritis

50 mg administered by subcutaneous (SC) injection once a month

Comments:
-Psoriatic arthritis (PsA) or ankylosing spondylitis (AS): May be given with or without methotrexate or other non-biologic Disease Modifying Antirheumatic Drugs (DMARDs).
-PsA or AS: Corticosteroids, non-biologic DMARDs, and/or NSAIDs may be continued during golimumab treatment.

Approved indications for this dose:
-Active psoriatic arthritis alone or in combination with methotrexate
-Active ankylosing spondylitis

Usual Adult Dose for Ulcerative Colitis

Initial dose: 200 mg administered by subcutaneous (SC) injection at week 0, followed by 100 mg at week 2.

Maintenance dose: 100 mg administered by subcutaneous injection at week 4 and every 4 weeks thereafter.

Approved indications for this dose: Moderate to severe ulcerative colitis (UC) with an inadequate response or intolerant to prior treatment or requiring continuous steroid therapy.

Usual Adult Dose for Rheumatoid Arthritis

Simponi (R): 50 mg administered by subcutaneous (SC) injection once a month.
or
Simponi Aria(R): 2 mg per kg given as an intravenous infusion over 30 minutes at weeks 0 and 4, then every 8 weeks thereafter.

Comments:
-Golimumab should be given in combination with methotrexate.
-Corticosteroids, non-biologic DMARDs, and/or NSAIDs may be continued during golimumab treatment.
-The efficacy and safety of switching between intravenous and subcutaneous formulations and routes of administration have not been established.

Approved indications for this dose:
-Moderately to severely active rheumatoid arthritis in combination with methotrexate

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

Data not available

Other Comments

Administration advice: Refer to the manufacturer's product information for complete administration instructions.

Storage requirements: Refrigerate (36 to 46 degrees Fahrenheit) and protect from light.

Got questions about Rheumatoid Arthritis? Get answers from our expert Dr. Carteron. Click Here

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