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Depakote ER User Reviews & Ratings (Page 4)

Depakote ER has an average rating of 7.4 out of 10 from a total of 95 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Depakote ER

  • Mysti
  • Taken for 2 to 5 years
  • February 21, 2021

For Bipolar Disorder "Thank you Depakote ER for giving me a new life. I take Prozac and Depakote ER for Bipolar. It has been a long road to accepting the fatigue but the dangerous uneven life I used to live I had to come to terms with it. I had horrible manic episodes on other medications that did not work. This combo is perfect except the fatigue is the hardest part. But I don’t have to suffer like that. I have breakthrough episodes but I can increase the Depa dose if needed. The only medicine that has changed me and allowed me to live a normal life"

10 / 10
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2 Report
  • Reb
  • Taken for 10 years or more
  • October 27, 2021

For Epilepsy "72 year old man with epilepsy diagnosed at 13. Many seizures as a young adult but Seizure free for approximately 30 years. Take 500mg Depakote ER twice a day and Dilantin 100mg two, twice a day. My side effect has been weight gain. But the medications have been very effective in my case."

8 / 10
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0 Report
  • Jano
  • Taken for 1 to 2 years
  • April 6, 2020

For Epilepsy "Depakote caused an increase in seizure occurence as well as severity of the seizures. Extreme changes in sleep habits, appetite, behavioral issues as well as severe and erratic mood changes, vomiting and regular kidney stones"

1 / 10
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0 Report
  • MJR
  • Taken for 6 months to 1 year
  • April 28, 2021

For Migraine Prevention "This has been the most helpful migraine preventative - my migraines were becoming a full-time disability and for the first time in a long time I’m hopeful - my doctor added 20-30 mg of Vyvanse (stimulant - a very low dose) to suppress appetite and lethargy and it is amazing - no appetite, no weight gain and I’m energetically working full-time. Fingers crossed it keeps working. Try the stimulant to prevent the weight gain!"

9 / 10
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0 Report
  • Anita...
  • Taken for 5 to 10 years
  • August 24, 2013

For Bipolar Disorder "This medicine has been great for me. I do not feel any side effects. I actually lost 25 pounds... I had been on lithium for 28 years."

10 / 10
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48 Report

Are you taking this medicine?

  • i2ano
  • Taken for 1 to 6 months
  • April 7, 2014

For Bipolar Disorder "Caused suicidal depression"

1 / 10
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32 Report
  • livel...
  • October 13, 2014

For Bipolar Disorder "Crushed mania fast on 2000 mg/d and currentyl stable on this dose"

10 / 10
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26 Report
  • HEDR
  • September 25, 2009

For Bipolar Disorder "Has helped to slow down my racing thoughts and helped with some of my sleeping issues."

8 / 10
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33 Report
  • Synta...
  • October 9, 2009

For Bipolar Disorder "Depakote in use with Zyprexa has given me my life back. I haven't felt this "normal" in many years."

10 / 10
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30 Report
  • be2
  • Taken for 2 to 5 years
  • June 30, 2015

For Bipolar Disorder "Very smooth mood stabilizer, no side effects. I take 1200 mg/d."

10 / 10
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20 Report
  • Corrie...
  • May 24, 2015

For Bipolar Disorder "I had a strong desire to drive off of the road even with other people in the car. Otherwise this worked well but the desire increased the longer I was on it."

7 / 10
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18 Report
  • crims...
  • January 14, 2012

For Migraine Prevention "This has worked better then anything else I've tried. I have gained weight though and I still get the flashes of light and dark spots. "

2 / 10
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18 Report
  • Kano
  • Taken for less than 1 month
  • May 12, 2018

For Bipolar Disorder "Terrible. Absolute poison. I would never ever put that toxic waste in my blood stream again. Depakote is bad."

1 / 10
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10 Report
  • Lilra...
  • September 8, 2009

For Mania "I have been taking Depakote ER for about 9 months. I have found it helpful for the mania. The bad side effect is that I gained about 30pounds."

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18 Report
  • why
  • Taken for less than 1 month
  • May 5, 2013

For Epilepsy "Severe pain all over after taking, so I had to stop."

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12 Report
  • nicmo...
  • June 16, 2009

For Epilepsy "I have taken Depakote ER for awhile with Lamictal. I have not had a seizure in 34 months. I do have hair loss and weight gain problem."

8 / 10
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13 Report
  • Anonymous
  • February 10, 2009

For Epilepsy "I took the medication for two years as a teenager. It stopped the seizures but I lost all my energy and put on 40 pounds. Once I stopped Depakote, I nearly lost all the weight within 2 months."

5 / 10
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13 Report
  • Joe
  • Taken for 2 to 5 years
  • July 3, 2019

For Epilepsy "Controls epilepsy but bad side effects: Worst was tremors which got worse until I got off drug. Replaced Depakote with Briviact."

2 / 10
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5 Report
  • JB34
  • Taken for 1 to 6 months
  • June 10, 2019

For Bipolar Disorder "Not sure if Depakote is worth it. Rather take Seroquel XR."

6 / 10
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5 Report
  • sunfl...
  • November 19, 2008

For Epilepsy "Been on for 10 Years. Do have break through seizures every 4-5 years (tonic-clonic)."

8 / 10
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8 Report
  • Mandy
  • Taken for 1 to 2 years
  • July 14, 2021

For Epilepsy "It stops my seizures but makes my hands shake like crazy. I can't even write. I shake much more when I have extreme anxiety"

10 / 10
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1 Report
  • Anonymous
  • November 4, 2009

For Migraine Prevention "Fewer side effects than Depakote but nearly no benefit for migraines."

4 / 10
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3 Report
  • D How...
  • Taken for 10 years or more
  • January 1, 2023

For Epilepsy "Very positive experience with Depakote, now Depakote ER. Monotherapy for tonic-clonic seizures since 1980s. No seizure since 2004. I take one125 mg per day."

10 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.