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Diclofenac / misoprostol User Reviews & Ratings

Brand names: Arthrotec

Diclofenac / misoprostol has an average rating of 8.2 out of 10 from a total of 53 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Diclofenac / misoprostol

  • not...
  • Taken for 10 years or more
  • July 7, 2013

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have been taking Arthrotec for 25 years and gradually have had to increase to get the same relief. I was taking 75 mg two times a day. My concern at this time is that my Kidneys have been slowly deteriorating over time and I did not even notice it until my doctor called me yesterday after some blood work and asked me to stop taking it. I am having blood work again Monday and I already know that my Kidneys are working better. It is a tough call because the pain is coming back full force. I also have Fibromyalgia and type 2 diabetes and other issues. I wish there was a way to find relief from pain without medicines and if you had asked me a week ago I would have told you that I would be hooked on Arthrotec and could not imagine life without it."

8 / 10
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116 Report
  • Jimmyk
  • March 3, 2013

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I was prescribed Arthrotec 75/0.2MG. I had spinal surgery on L5 in 2001 by an orthopedist and in 2009 on same disc by a neurosurgeon. In 2009, I took a long time to recover. Also, I am suffering from degenerative disc disease on S1 to the point of self fusion (a good thing as it stabilized my lower back). In 2009, I was prescribed Arthrotec 75 / 0.2MG I found this to be a miracle. I only take it as needed and only when it wears off. Once a week or as needed. FANTASTIC results! It takes years off my body. I am 62."

10 / 10
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113 Report
  • nomor...
  • Taken for 6 months to 1 year
  • December 19, 2012

Arthrotec (diclofenac / misoprostol) for Sciatica "I was prescribed Arthrotec 8 months ago for a bulging L5S1 disc that was causing me excruciating sciatica pain. At the time, the Arthrotec did nothing for the pain which led to me getting 2 epidural steroid injections. Those two did not work, and I haven't been taking any medicine and instead working on controlling my stress levels which seems to have helped. In the past 2 weeks, the sciatica has flared up really bad to the point that I can't sit or stand for any length of time. In desperation I took the Arthrotec to see if it would knock down the pain and BOOM- I seriously felt like a new person. I don't know why this didn't work for me the first time, but now it is working perfectly. It's a miracle in my mind."

9 / 10
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95 Report
  • ardie
  • July 11, 2008

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I just started Arthotec 75 mg two days ago. I can't believe that after 2 pills I was feeling no pain. My legs were working, I could walk normally, my spine wasn't hurting and my feet were pain free. This is a new life for me. I have been in constant pain for a long time and needed injections in my feet and spine to cope. I am ready to tell the world how well this is working for me."

10 / 10
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103 Report
  • SySa
  • November 19, 2016

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have been on Arthrotec for 23 yrs now and can not recommend it for everyone but for me it was a life saver. I have RA and went threw many back surgeries (7) to repair degenerated disks. For a year I was in a wheel chair unable to walk and never left the house. MANY doctors told me that I had to resolve myself to living a life of a person who only has limited mobility. My intern a young man right out of med school recommended this. In the last 23 years I have lived a full and VERY active life and could keep up with a 35yr old (im 77 now). It saved my life , I could not live without it, I am active, travel, have sex and do anything I could (almost) when I was 50. For me it is wonder drug..."

10 / 10
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56 Report

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  • ldmf
  • Taken for less than 1 month
  • August 24, 2012

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have been in pain for years and have been on Cymbalta, gabapentin and Tylenol 3 for 2 and a half years. I suffer from arthritis and herniated discs, degenerative disc disease. Yesterday my doctor put me on Arthrotec 50mg. It made me sick to my stomach but my pain was mostly gone. I could actually put on a pair of pants and socks without my hips and back hurting. I'm 34 and hope to live a long life and being in pain everyday was making me depressed. I think there is hope. So far so good with Arthrotec."

7 / 10
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75 Report
  • havai...
  • May 19, 2008

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I tried Celebex and other drugs to releived joint pain in the ankles, knees, wrist and fingers with little relief. 3 days on Arthrotec 75, only once a day and I was almost as good as new. Able to work on the treadmill, take long hikes, write and type. Maybe the best part was not waking up at night with pain in all the fingers. By accident, I also found that taking one pill ever other day is suffient for me."

10 / 10
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94 Report
  • Anonymous
  • January 20, 2011

Arthrotec (diclofenac / misoprostol) for Sciatica "I was suffering from sciatica, herniated and bulging disc L5-L6. Had multiple epidural shots and radiofrequency, which gave temporary relief. I had been prescribed Arthrotec a while back but did not take it until pain was unbearable lately. I could not get comfortable whether I was standing, sitting or lying down. Driving was also torture. Within 2 days of taking Arthrotec 75 (2X daily), my pain disappeared almost completely. After reading comments, I will try 1 pill per day to see if it sustains."

9 / 10
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81 Report
  • Judys
  • Taken for less than 1 month
  • February 21, 2013

Arthrotec (diclofenac / misoprostol) for Rheumatoid Arthritis "I have been living with 4 swollen fingers on my right hand (my dominant hand) and have trouble sleeping with pain in both hips and shoulders. At 49 I feel far too young for arthritis, but sometimes life is not fair. Dr prescribed Arthrotec yesterday. 2 pills in and I can hold a pen, type and slept like a baby last night! I'll take the queasy stomach and gas if it means I'm not cranky because of poor sleep and constant pain!"

9 / 10
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66 Report
  • Rita
  • June 26, 2013

Arthrotec (diclofenac / misoprostol) "I have been taking Arthrotec for two days now. I feel a lot better. Today I can walk, stand up and sit. The only problem is it makes me feel hungry all day. Its like I haven't eaten even though I did 10 minutes ago."

8 / 10
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64 Report
  • Falco...
  • Taken for less than 1 month
  • January 13, 2013

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I am 73 and just found out I have torn ligaments, tendonitis and arthritis in both wrists. For about a year now I have had stabbing pains in my wrists and hands. After taking three Arthrotec 50 my pain is gone. But, I also have a gastric problem with reflux and for the last two nights have had extreme bloating and reflux. I took the fifth tablet this evening. It is so bad tonight that I have to stay awake. I can not go to sleep, even while sitting up in a chair for fear of having the reflux again. I have had the reflux two times already tonight when I dosed off. So I am here now typing this at 4:30 AM so I do not fall asleep again. The Arthrotec works, but I can not take any more of them."

10 / 10
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64 Report
  • Windb...
  • March 19, 2012

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have osteoarthrititis, rheumatoid arthritis, fibromyalgia and sciatica and have tried many other pain medicines with Celebrix being the last. I am taking Arthrotec 50mg 3x a day and by the second day I was very pleased with the results. My pain has lessened from a 7-8 down to a 2-4 level. I have Vicodin as a stand by and haven't taken any this past month, I went from taking 1 to 3 a day to none, that is a good thing!!"

9 / 10
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66 Report
  • Anonymous
  • July 6, 2011

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "Was given Arthrotec 75 (1x/day) for residual pain following a car accident. Got to the point I could barely walk most days and, on my best days, would have very little endurance for walking or even standing. By day 2 of taking Arthrotec 75, I felt like I was made whole again. It is my wonder drug. Found I can skip a day and be okay if not too much physical activity, and at times have taken a 2nd dose midday during more strenuous activities. No side effects that I have noticed. I don't like taking medicines so I hope I won't need to take these for too long, but so grateful for them right now. I can actually do things for myself again."

10 / 10
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64 Report
  • Txtam...
  • April 2, 2011

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I'm a 40 year old Mom with stage 4 breast cancer with metastasis to bone from head to toe. As you can imagine, I'm in considerable pain all the time. They have kept upping my morphine and although going without the morphine is not an option I am tired of doubling it all the time. I since gone to a pain doctor that prescribed Arthrotec 75 and at last I can go hiking with my kids again. I can go shopping with them and not be exhausted from pain. I am very grateful to Arthrotec 75 because it has given me a piece of my life back. The only side effects I've had from it is a little bit of an achy stomach and I've been very gassy. Well worth the trade off."

9 / 10
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61 Report
  • HarryG
  • October 26, 2010

Arthrotec (diclofenac / misoprostol) for Sciatica "Arthrotec75 was prescribed after I developed serious aching in my right thigh that prevented me from standing or walking for more than a few minutes. Eventually, a herniated disc at L-4-L5 was diagnosed. A large fragment was pressing up against a nerve. After a few more weeks, the onset of motor deficit in my foot led to the need to have surgery. If that hadn't happened, I might have been able to avoid the surgery indefinitely by continuing to take Arthrotec. Other NSAIDs might have worked too, but protection of the stomach lining by Arthrotec's misoprostol was appealing."

9 / 10
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61 Report
  • cuddles
  • May 5, 2015

Arthrotec (diclofenac / misoprostol) for Sciatica "I have suffered with sciatica for 3 years and now have pain in my right foot along the arch. I took this medication when I was first diagnosed and it did nothing to relieve the pain. I decided to give it another shot last week because of the foot pain and it started helping right away with both issues. The only problem I have is I am bloated and feel like I have gained 10lbs! This is a huge bummer since I am also on a weight loss plan! But I will keep taking it for now."

9 / 10
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41 Report
  • allyo...
  • June 12, 2010

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I had been taking Arthrotec 75mg 2 X's per day for several years and it worked great! No more severe pain in my lower back but HUMANA decided I didn't need it any longer, just because there was no generic for it. Now I live in severe pain daily. Other medicines either do not work or they hurt my stomach so bad I can't take them. I miss my Arthrotec. "

10 / 10
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52 Report
  • Chevy
  • March 27, 2011

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I love Arthrotec and did not realize just how well it was working for me until I switched to Celebrex, which did nothing. Within days on Celebrex I was so stiff I could hardly walk. I have back issues from arthritis (nerve impingement, etc.) and have epidural spinal injections. I promptly went right back to the Arthrotec. But, I do realize now that the Arthrotec does make me very drowsy and hungry. The hunger and cravings is really strange, but during the time on Celebrex I wasn't hungry at all while dieting. So, it's either pain and stiffness, or drowsiness and hunger. I chose not to have pain."

9 / 10
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49 Report
  • MrTony
  • November 21, 2009

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "This is a wonder drug! I have not been able to lie down for more than a few hours for years. Since I started Arthrotec 75 I can stay in bed 8 hours with almost NO pain. I have painful hips and shoulders."

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52 Report
  • giblet
  • September 9, 2010

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I found this medicine relieved my pain very well. I was taking 75 mg twice a day and this did me very well. Except I had a side effect that caused me concern. I gained 25 pounds and could not lose this weight. Gaining weight is not good when you suffer arthritis. Until I was taken off this drug I could not lose weight and kept gaining. When I was off it I lost 5 pounds in one month and now have lost 20 of the 25 I gained. "

5 / 10
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50 Report
  • DRano
  • Taken for 10 years or more
  • October 29, 2019

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have been on Arthrotec 50mg three times daily for 25 years. I have never experienced any of the negative symptoms some other reviewers have mentioned. I have severe osteoarthritis. It is especially severe in my spine. As a result I have had numerous surgeries, fusions etc. each time before and following surgery I am told to stop taking Arthrotec for an extended time. Two weeks ago I had cervical spine surgery, so no arthrotec. Today I can hardly walk up and down stairs or get out of a chair! I am 77 yrs old and in good health. I weigh only 117 so it is not my weight that is holding me back. For me Arthrotec is a firm 10!"

10 / 10
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21 Report
  • Kristym
  • November 14, 2011

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "Lupus: I have been taking Arthrotec for two weeks now; my symptoms have improved tremedously. I tired Mobic 15 mg., Celebrex, Lyrica and just about everything else that would decrease pain. I know it has side effects but walking and being productive is well worth the risk."

10 / 10
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43 Report
  • Dave...
  • October 1, 2015

Arthrotec (diclofenac / misoprostol) for Rheumatoid Arthritis "I recently switched from Celebrex to Arthroc. Although my stomach has been very upset most days, the pain in my shoulders, hips and knee has been greatly reduced. Also, I have gained considerable mobility in the range of motion in my leg/knee."

8 / 10
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32 Report
  • soozi...
  • Taken for 5 to 10 years
  • November 8, 2013

For Osteoarthritis "Prescibed two arthrotec 75 daily plus two tramadol due to osteoarthritis in both knees had to drop to one arthrotec taken in the morning due to reflux and vomit during night.Feel hunger constantly even when fed.Weight hard to manage and can still feel sick and dizzy with a burbling stomach for hours after taking arthrotec"

4 / 10
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35 Report
  • Robbear
  • Taken for 10 years or more
  • July 30, 2020

Arthrotec (diclofenac / misoprostol) for Osteoarthritis "I have had problems with my back for decades. Now, at 73, the challenges are worse. The family doctor says my whole back is degenerating (arthritis and compressed discs primarily). I have used Arthrotec in the past (at 50 mg. or 75 mg.). I got away from it when I developed chronic kidney disease. My family doctor has me on Tylenol Arthritis (the maximum amount I can take). I've been taking that for a while, but now I'm getting breakthrough pain. My kidney specialist said Arthrotec would be ideal for breakthrough, but no more than one tablet a day. It all works. I am very happy with the results."

9 / 10
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13 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.