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Chlorthalidone User Reviews & Ratings (Page 2)

Chlorthalidone has an average rating of 3.6 out of 10 from a total of 45 reviews on Drugs.com. 18% of reviewers reported a positive experience, while 62% reported a negative experience.

Reviews for Chlorthalidone

  • Pam
  • Taken for less than 1 month
  • May 24, 2023

For High Blood Pressure "Horrible medicine. I had only been on this for 5 days but they are now they are in the garbage. The side effects I have had are severe. Sharp jabbing pains under the rib cage, very bad back and joint pain, EXTREME tiredness, headache, and severe cotton mouth. I can't believe doctors still prescribe this. To the doctors: read patient reviews and warn your patients prior to prescribing! Instead of using this medication try eating three kiwi fruit a day and a couple of glasses of beet juice. That does a better job of lowering blood pressure with no side effects and is overall better for your health. It worked for me!"

1 / 10
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8 Report
  • John-S
  • September 3, 2016

For Edema "I am 57 with sporadic edema, and was given this drug because I asked for something less powerful than what I was taking. 2 days later, I was in the emergency room, having difficulty breathing and racing heart rate with almost no exertion. Symptoms went away a day after stopping the drug. Perhaps my physician mis-prescribed this but it almost did me in. Awful reaction."

1 / 10
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37 Report
  • TeriseD
  • Taken for less than 1 month
  • May 20, 2022

For Edema "Pitting edema in both legs and feet for over two years. Tried many loop diuretics but they did absolutely nothing to reduce fluid, and previous doctor never suggested thiazide type diuretics nor seemed interested in finding out what was causing my edema so I finally found a new doc. She put me on 25mg chlorthalidone every day which worked very well. I lost 15 pounds of fluid within two weeks and my legs were back to normal. However my sodium level dropped to 129 and my doctor asked me to discontinue taking it. But she also forgot to tell me to reduce fluid intake and I'm pretty sure that's why my sodium dropped. Trying again with a 15mg dose and restricting fluid intake to 1.5 liters a day or less. Will update my experience in a couple weeks."

9 / 10
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11 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • January 3, 2023

For High Blood Pressure "While the medication seems to work, the side effects are unacceptable. My dose is 25 mg. It leaves me very lightheaded all day and with absolutely no energy at all. I spend most of the day in bed. My muscles become very fatigued with minimal exertion and I develop rapid heartbeat and respirations."

4 / 10
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8 Report
  • EDS
  • Taken for 5 to 10 years
  • March 11, 2020

For High Blood Pressure "This drug is amazing. Using it for about 8 years and 25mg is all I need to keep my pressure under control. The best part is it's inexpensive and has virtually no side effects (potassium is an issue as with all diuretics and sometimes I get a rash). I tried hydrochlorothiazide and it was useless. This is the only one for me."

10 / 10
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16 Report

Are you taking this medicine?

  • Miss...
  • Taken for less than 1 month
  • April 11, 2023

For Edema "THIS DRUG IS DANGEROUS!!! Doctor prescribed chlorthalidone for fluid retention. I took it for 4 days. I begin experiencing extreme cramping on day 2. Got diarrhea, cramping from the neck down so severe I was in tears. It tore my stomach up. Day seven (note I haven't taken any more for 3 days) I am still recovering from the stomach pain and diarrhea. I'm rating this drug a 1. What good is it if you can't take it because the side effects are so severe."

1 / 10
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5 Report
  • Jewelee
  • Taken for less than 1 month
  • December 16, 2022

For High Blood Pressure "Been on this for 5 days and my heart races very high just standing and I am out of breath just standing at the kitchen sink. Heartbeat would jump up 150 just standing. For the last 2 nights when I get up to go pees, I feel my body being way off. Not like dizziness but falling. I almost fell in the tub last night. Now today I can’t eat or it makes me really sick to my stomach."

1 / 10
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6 Report
  • Lilmiss
  • Taken for 6 months to 1 year
  • February 19, 2022

For High Blood Pressure "I started Chlorthalidone for newly diagnosed HBP and it worked immediately. At first no side effects AT ALL. THEN I realized I always had muscle aches and I found myself sleeping more and more. I'd go to sleep at night take my son to school and come back home to sleep another 5 hours. I now always have chest pressure AND THE WORST. I had 4 cavities within months of starting it. My dentist was shocked. I was in my 40s and had NEVER had a single cavity. He immediately expressed his concern, asked about what I'm doing that might cause dry mouth and told me to talk to my Dr about my new medication but when I mentioned it as a side note on my visit he didn't think anything of it. NOW my gums have receded to nearly NOTHING. This can't be reversed! I'm so afraid I'm losing ALL OF MY TEETH and have only been on this a year!!!"

1 / 10
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8 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • April 7, 2023

For High Blood Pressure "I was started on chlorthalidone because losartan didn't lower my blood pressure and I was having too many side effects with lisinopril. It lowered my blood pressure well for a few months and then seemed to stop working. During these three months, I was also dealing with heart palpitations. I completely stopped caffeine and alcohol. I had a halter monitor test and was told I was experiencing harmless PVCs and PACs. My doctor doubled my chlorthalidone to try to get my BP back under control and then I started to feel really terrible. Headaches, muscle cramping all over my body, weakness, fatigue, frequent heart palpations. I thought it was just a little bit of dehydration since this medication is a diuretic but my labs showed that my potassium dropped to severely low. I was taken off the medication and had my potassium replaced. Once my potassium was back to normal I started to feel better and after a few weeks, I also noticed that my heart palpitations had completely stopped."

2 / 10
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4 Report
  • sanann
  • Taken for 1 to 6 months
  • November 4, 2021

For High Blood Pressure "I was prescribed 25mg to add to another B/P Med I was taking, as my B/P was always over 136 - 155 systolic. I myself reduced it to 1/2 tab after 6 weeks as so lightheaded + up to toilet 3 -4 times a night! Have just stopped it today after 8.5 weeks as even though I'm fit, (73 years) I'm finding I now cannot get up steep hills without constantly stopping. I'm in training to do a 2 day tramp/hike in a week and got so scared yesterday when at my very large local library and walking up four flights of stairs, I had to stop halfway up second staircase - got the lift! so my B/P now always 114/74 to 126/86 and I drink lots of water, don't drink alcohol. Just not worth the weak feeling in my legs and the fainting feeling throughout my body."

2 / 10
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6 Report
  • Dakota...
  • Taken for less than 1 month
  • April 4, 2023

Hygroton (chlorthalidone) for High Blood Pressure "Just started taking this a week ago. Has not yet effectively lowered BP 150/90. I have had side effects of cold sweats, weakness, nausea, and erectile disfunction, in order of severity. Planning to contact my doctor if symptoms do not lessen within another week."

1 / 10
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3 Report
  • Pisse...
  • Taken for 5 to 10 years
  • February 17, 2022

For High Blood Pressure "Horrid ! I can’t get off the damn pills ! Didn’t help with bp at all, but my kidneys now will not work without this stuff I literally gain a pound and hour of I stop taking it! Worst decision ever! Side effects are the ones making my life dependent on a drug that I didn’t need in the first place!"

1 / 10
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5 Report
  • TeriseD
  • Taken for 1 to 6 months
  • July 13, 2022

For Edema "After 2 months of being on 25mg chlorthalidone for pitting edema and losing 15 lbs of fluid in my legs it stopped working. Experienced side effects of low sodium and chloride levels and dehydration but stuck with it since the effects of edema were worse. Weight had stabilized, but then started gaining a pound a day. Dose was increased to 50mg but had no effect and continued to gain original fluid back. I've already tried so many different diuretics, including both loop and thiazide types, and none worked at all until chlorthalidone. I'm tired and frustrated that doctor can't even figure out what's causing the edema, which at this point is several years."

5 / 10
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2 Report
  • Jtano
  • Taken for 1 to 6 months
  • January 4, 2020

For High Blood Pressure "Chlorthalidone gave me horrible migraines, ear pressure and intermittent episodes of confusion and loss of balance. It did significantly lower my BP but, the side effects weren’t worth it."

4 / 10
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34 Report
  • semin...
  • Taken for less than 1 month
  • October 6, 2013

For High Blood Pressure "Caused fatigue, leg cramps, nausea."

6 / 10
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46 Report
  • Jtano
  • Taken for 1 to 6 months
  • December 22, 2019

For High Blood Pressure "It worked well at decreasing my systolic BP but, gave me horrible migraines. I also had pins and needles in my feet and some days I felt really weak and out of it like I had an electrolyte problem."

4 / 10
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18 Report
  • RCano
  • Taken for less than 1 month
  • October 23, 2020

For High Blood Pressure "Hoarse, dizzy, joint pain, acne, depression, no energy, no thanks."

1 / 10
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15 Report
  • Niecy
  • Taken for 1 to 6 months
  • August 15, 2021

For High Blood Pressure "Makes my legs feel like wet noodles ; very weak and tired. Is this medicine or poison ?"

7 / 10
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8 Report
  • Mary
  • Taken for less than 1 month
  • January 29, 2021

For Edema "I force myself to take this, but just can't do it. I was experienced severe short of breath all day. I pee more without this pill. Very bad and painful experience, my chest and back are still sore."

1 / 10
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7 Report
  • Anonymous
  • October 29, 2022

For High Blood Pressure "Side effects of chlorthalidone were brain fog, dizziness, upset stomach, it is a horrible med. Had to stop after third dose."

2 / 10
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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.