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Wellbutrin SR for Depression User Reviews (Page 4)

Wellbutrin SR has an average rating of 6.8 out of 10 from a total of 96 reviews for the treatment of Depression. 56% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Wellbutrin SR

  • world...
  • September 4, 2009

"Wellbutrin is the only antidepressant that has worked for me. I've tried 7 other kinds and all made me worse. Wellbutrins initial side effects were mild, mainly headache and nausea. But I noticed I was happier and more worry-free after a few weeks. I have to admit that this medicine made my appetite worse. I know its sometimes prescribed to help with obesity but it made me gain weight. If you are a smoker be careful because it will make you sick if you smoke, which is why I was able to quit smoking."

8 / 10
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41 Report
  • Slynne
  • September 5, 2010

"I'm on my 5th day of starting Welbutrin SR (generic) 100mg and feel more energetic and less depressed and lethargic. That could be a placebo effect so early in treatment, but I know for sure that its almost completey taken away my appetite. I actually forget to eat. I had been on Prozac, which worked great at first and then the therapeutic effects seemed to fade over the months until I was severely depressed again. This has happened to me with several other antidepressants as well. I hope that Welbutrin will work consistently for me. So far I'm very happy with the results."

7 / 10
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38 Report
  • Txmama
  • Taken for less than 1 month
  • December 15, 2015

"I started this after talking to my doctor about how I was scared to gain weight with an antidepressant (I gained 15 pounds on Zoloft). This medicine made me feel crazy! I took it for 2 weeks, and every day I felt like there was a brick on my eyes/head. I felt like I was going to have a seizure any moment (no I've never had one, I just felt like I was going to). I was sensitive to light, and couldn't see when I was driving at night. It was awful!!! I'm on Prozac now and seem to be doing ok :)"

1 / 10
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26 Report

Frequently asked questions

  • 17...
  • December 19, 2010

"I have been on this medication for less than a month already and to be honest I still haven't noticed anything too big yet. I have severe depression and have tried four other medications and all they did was make me tired and antisocial. With this I don't fall asleep during class or eat a lot but I still feel like I'm not completely here. I feel sad and I have been crying a lot for small things but I'm still giving it time and I feel confident about this."

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36 Report
  • Anon
  • Taken for 6 months to 1 year
  • December 30, 2018

"I took wellbutrin 150mg for 1 week then 300mg for about 5 maybe 6 months and then my doctor increased my dosage to 400 mg mixed with 100mg of Zoloft and I'm shaky, irritated and more prone to crying. I have split personality disorder and its been throwing me into different ones and on top of that I have PTSD and mood disorder plus I'm bi polar type 2 and I've been thrown into my manic states more often. It sucks."

2 / 10
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18 Report

Are you taking this medicine?

  • Joano
  • November 8, 2018

" I feel the same way as someone else on here - super irritated and angry . Have ruminations of the past. I'm stopping it today. I have a mood disorder and this makes it bad. Plus I feel weepy too. I can deal with the depression until I find a better med."

5 / 10
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18 Report
  • 89UY6...
  • November 24, 2009

"I have been prescribed many medications and I must say that Wellbutrin has been my life saver. I can honestly say that not all medicines are right for everyone. If you feel that you current medicines are not helping... please talk to your doctor."

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36 Report

More FAQ

  • kkenyon
  • February 22, 2009

"I started Wellbutrin 5 days ago. The first night I felt like my heart was racing and pounding but it went away the next day. Then at work for the past 2 days I have been sweating excessivley and getting the feeling that I need to sit. Last night after taking the medication for 5 days I had the feeling that my head weighed a 1000 pounds and I just felt so dizzy, lightheaded, and weak I could barely walk right. I went to lay down to sleep and all of a sudden I couldn't swallow and was gasping for air. It was so scary. I just couldn't catch my breath. I could feel my throat closing up. I was rushed to E.R and they found I was having an allergic reaction to it."

3 / 10
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37 Report
  • Anonymous
  • July 10, 2011

"I used this on and off for several years, never over 150 mg/day. I liked the energy it provided, the suppression of appetite, the low cost (without insurance) and the increased sex drive (as opposed to Prozac/Zoloft which prevented me from reaching orgasm). The downside for me was increased sweating and anxiety. The anxiety was the worst. I now use Ritalin and prefer it."

7 / 10
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32 Report
  • mihulka
  • January 15, 2018

"I've been taking this medication off and on for quite a few years and I have mixed feelings about it. If you want lots of energy this is the stuff to take. If you have OCD or an anxiety disorder you might want to pair this with some Effexor or Zoloft. I'm still in the process of figuring out a dose that works good for me. I'm on 450mg xl and 75mg Effexor xl. If you want to drink alcohol keep it to a minimum preferably no more than 3 beers I personally find that it reduces my desire to drink and I'm also going to ask doctor about taking Contrave which is 300 mg Wellbutrin and 12.5 mg Naltrexone for weight loss (Thanks Effexor)"

6 / 10
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19 Report
  • Anonymous
  • December 15, 2010

"I have Major Depressive Disorder, Anxiety, and severe ADHD. I took Wellbutrin for four days and at first it was fine then I quickly developed hot flashes and eventually started freaking out and having unrelenting suicidal thoughts. Guess it just didn't work for me, but it didn't make me tired."

1 / 10
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26 Report
  • Anonymous
  • September 8, 2010

"I have been taking Wellbutrin SR 150mg for five years. Have been doing really well, but here lately I have been really tired, low sex drive, wanting to eat when I am not hungry. Maybe I need an increase."

8 / 10
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26 Report
  • 601mo...
  • September 22, 2016

"I have been on this med for two weeks now and i have yet felt any benefits while starting this med. My doctor told me to take it twice daily they are 100mg. I have been taking it but still feel the same."

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  • Nicky...
  • January 25, 2021

"I don't find this an antidepressant rather than a demeanor stimulant/energy enhancer. Goes well with SSRI's, SNRI's and many others as add-on. Personally on 150mg daily I found myself more energetic, needing less sleep, more able to focus for seriously long days, more outspoken and also more irritable. Some restlessness or a stupor-kind of feeling for a couple hours in the afternoon. All of this subsided as the months passed. 1-2 years lead to some kind of tolerance. 300mg doses seemed to give me some more focus but also made feel a bit off. Enhances the focus a little more, and likely possible overt wakefulness, irritability or confusion would subside over time. I still couldn't estimate needing such a dose myself. Initially, a combination of Sertraline and made me hypermanic for a month or two: showed up at parties drinking and talking to everyone, making new acquaintances, life choices ultimately leading to major changes etc. My psychiatrist didn't think it was a problem, though."

7 / 10
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8 Report
  • Pris
  • Taken for 1 to 6 months
  • December 28, 2020

"I’ve been talking Wellbutrin for a couple months now and honestly mood wise I have been feeling better. I still have big mood swings (diagnosed with bipolar type2) so it really could be that. Side effects I have noticed would be extreme agitation and severe acne which honestly is disappointing because I used to have really clean and clear skin. Other than that I think it’s pretty cool."

8 / 10
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7 Report
  • Bonkey
  • Taken for 6 months to 1 year
  • July 28, 2022

"I started on zoloft for depression. Worked wonders, but I had difficulty reaching orgasm and next to no sex drive. Doc prescribed wellbutrin, and it helped, but I was still experiencing sexual dysfunction. I had no trouble reaching orgasm, but it felt like nothing. There was a build up, but no fireworks. Just a faint sense of relief from tension. I was cycled through buspirone, remeron, and trintellix before I gave up on SSRIs altogether. It's been two months on just wellbutrin, and orgasms have gotten better, but they're still not what they were before medication. I'm going to continue taking it, but I'm concerned about the lasting effects from the SSRIs."

8 / 10
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  • Count...
  • Taken for less than 1 month
  • February 13, 2021

"I started taking Wellbutrin SR 150 mg twice a day for my depression and to quit smoking, everything was getting better, I had a great night sleep by day 2 felt a little lighter with my mood, then on day 4 I felt wrong, and by my nighttime dose I ended up giving a seizure, which I have no history of, and again no sleep and tremors and horrible sweating, I was really hoping this was going to help me but I have never been so scared in my life as I was when I lost control of all my muscles and it took 2 days to start to feel better from it. My muscles hurt, extreme anxiety and insomnia.. be very careful with this drug!"

2 / 10
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6 Report
  • Skeptic
  • March 10, 2009

"Good for depression, not for anxiety/depression. I had a history of General Anxiety, it got worse after menopause. I was on different SSRI's, the side effects were awful. When my depression returned, my doctor had me try Wellbutrin SL. It caused agitation, loss of appetite, muscle tremor and sleep disturbances were the worst. It does not help my anxiety, but it did helped depression. I am off it now to try something else in a week."

5 / 10
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17 Report
  • Mel
  • Taken for 10 years or more
  • April 4, 2020

"I been taking it over 15 years it has saved my life "

10 / 10
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67 Report
  • Rosie
  • Taken for 1 to 6 months
  • February 24, 2015

"Major change in my mood and energy. I enjoy to do things I used to do. Wellbutrin has changed my life."

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121 Report
  • Anonymous
  • January 19, 2009

"I have been taking Wellbutrin SR to treat stress related depression. I have had no side effects and have experienced a large increase in my libido. I feel like a kid again."

10 / 10
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95 Report
  • MamaB...
  • Taken for 1 to 6 months
  • December 9, 2018

"I have found this medicine to be very good for me. I'm taking 150mg three times a day It has also helped me with losing some weight . My Klonopin works well with it"

10 / 10
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36 Report
  • jay-bee
  • Taken for 6 months to 1 year
  • November 20, 2014

"Extreme dry mouth. Could not leave home without bottle of water. Extreme dry stools to the point that I was taking a stool softener every day to avoid unnecessary straining. "

3 / 10
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45 Report
  • Ht1990
  • Taken for 1 to 6 months
  • August 10, 2018

"Switched to Wellbutrin after being on zoloft for two years and it has been awful. I suffer from depression, PTSD and anxiety. Wellbutrin has made me extremely irritable and I'm constantly tired."

1 / 10
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22 Report
  • Anonymous
  • Taken for less than 1 month
  • December 21, 2017

"I like this medication but sometimes I feel angrier than I should be. I’m very quick to snap sooooo IDK if it’s this medicine or what"

6 / 10
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22 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.