Skip to main content

Acetaminophen / aspirin / caffeine User Reviews & Ratings

Brand names: Excedrin, Excedrin Migraine, Migraine Relief, Goody's Headache Powders, Excedrin Extra Strength, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Goody's Extra-Strength Headache Powders, Migraine Formula, Goody's Extra Strength, CVS Extra Strength Headache Relief, Bayer Migraine Formula, Arthriten, Pamprin Max Menstrual Pain Relief, ConRx Pain Reliever, Genace, Anacin Advanced Headache Formula, PainAid Extra-Strength Formula Medique Pain-Off Vanquish Extra Pain Relief …show all brand names

Acetaminophen / aspirin / caffeine has an average rating of 7.0 out of 10 from a total of 391 reviews on Drugs.com. 61% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Acetaminophen / aspirin / caffeine

  • Anony...
  • February 21, 2010

Excedrin Migraine (acetaminophen / aspirin / caffeine) for Migraine "Like all medications I've ever taken, I followed the directions exactly ("take 2 caplets with a glass of water") and the product worked great, with no side effects. With regard to those complaining that the product was ineffective or gave you bad side effects, PLEASE read the following. Although Excedrin Migraine and Excedrin Extra Strength are the exact same product, it is vitally important to follow the Excedrin Migraine directions if you are taking the pills for a migraine, NOT the directions for Extra Strength Excedrin! Here's why. Many people have incorrectly assumed that because the two products are exactly the same, which they indeed are, that the directions are also the same. THIS IS COMPLETELY FALSE. The reason that there is a separate product solely for migraines, and the FDA approved it solely for migraine use only, is because the amount you take for migraines is completely different than for general pain relief, including "regular" headaches. The reason Excedrin Migraine instructs you to take only 2 pills in 24 hours (vs 8 pills in 24 hours for Extra Strength Excedrin) is because taking more than 2 pills in 24 hours (for a migraine) is likely to cause rebound migraines for many people. In other words, taking more pills than the directions tell you to will make your migraine problem worse! You will note on the Excedrin Migraine package that the ONLY use for the product is "treats migraines." Think about that! The directions match that one usage and this is the reason the FDA approved the product. So if you have migraines and want to buy Extra Strength Excedrin, instead of Excedrin Migraine, that's totally fine, but be sure to follow the Excedrin Migraine directions! If you're taking the product for migraines and you take more than 2 pills in 24 hours, you can definitely except to experience the bad side effects that many people have talked about on this site! And keep in mind that although you should NEVER take more than 2 pills in 24 hours (if your using it for migraines), that doesn't mean you can't take just 1 pill in 24 hours. For some people, just 1 pill will get rid of your migraine. If 1 pill isn't working for you, then you can always take another one during each 24 hours. So less is fine, but more is a huge mistake. I hope I've made my point. Review sites in general tend to attract people who have bad things to say about a product. People who have a good experience with a product are much less likely to post their comments on a site like this. Why? Because angry people want to vent. This is not to say that some people who complain are insincere or haven't followed the directions of the product. There are always going to be people who a product just doesn't work for. But most people who properly follow the directions will not have bad results. Also, for migraines specifically, finding a product that truly gets rid of them can be very difficult for many people. It's trial and error. If one product doesn't work, you try another until you hopefully find one that does the trick. So a product not getting rid of your migraines is one thing, but having painful or uncomfortable side effects is another. Follow the directions and you most likely will never have the bad side effects. Whether it works to get rid of your migraine is a coin toss, but at least you won't have the bad side effects in most cases. I hope this helped. Good luck to all migraine sufferers. I know how awful they are."

8 / 10
Was this helpful?YesNo
119 Report
  • Anonymous
  • Taken for 10 years or more
  • September 30, 2012

Excedrin Migraine (acetaminophen / aspirin / caffeine) for Migraine "I have had migraines for almost 40 years. I have the type where I lose my central vision and have a halo effect for appx 45 minutes, then horrible pain sets in, and throw up for several hours. This will last for appx 8 hours, then the pain eases off and lingers for almost two days. I usually ended up at the hospital where I have had Demerol, Imitrex, etc, which did not work. One day I lost my vision, and tried Excedrin Migraine. This stopped the migraine cold. Never before had any medication even slightly reduced my pain and nausea. This was 14 years ago. I take two as soon as I start to lose my vision, wait until the halo effect subsides, then I can go about my day. Excedrin Migraine returned my life to me."

10 / 10
Was this helpful?YesNo
56 Report
  • Elliot
  • Taken for 10 years or more
  • August 26, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "It’s not just the new packaging it’s the formula it has changed and is horrible I’ve taken Goody's for 30 years . This is such a big disappointment .This company is going to sink fast !!!! This was a huge mistake!!!!!!!!!!!!"

1 / 10
Was this helpful?YesNo
28 Report
  • Lisa
  • Taken for 10 years or more
  • February 17, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I have take Goody powders for 25 years for back pain. I love the product but hate the new packages. It makes it harder to take. I have always heard if it ain't broke don't fix it. You should have left it alone."

8 / 10
Was this helpful?YesNo
29 Report
  • Mitch
  • Taken for 10 years or more
  • August 22, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "The new packaging stinks. Usually a large portion of the powder gets stuck in the bottom of the packet. When that happens instead on one clean dose in the back of your throat, now it dribbles out onto the tongue (which is a very bitter tasting ordeal). When the old pack emptied in to the rear of the throat there was minimal issue with bitterness. This is something that was not broken and did not need fixing. . What idiot thought this was a good idea? I have used Goody's Powder for decades. I am going elsewhere."

7 / 10
Was this helpful?YesNo
24 Report

Are you taking this medicine?

  • Jim
  • Taken for less than 1 month
  • August 14, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "SOOOO nice to see that EVERYone is in agreement on this! I've actually been driving around, snatching up all of the old packaging Goody's I can find. I just ran out a few days ago, and had to resort to buying the new crappy packaging. I actually held on to one of the old-style waxed envelopes, and I'll pour the contents from the new packaging into the OLD-style wax envelope, and THEN take the powder! I will now officially add MY voice to "the choir".... BRING BACK THE ORIGINAL PACKAGING! PLEASE!!!!!"

10 / 10
Was this helpful?YesNo
24 Report
  • Jeanne
  • Taken for 10 years or more
  • December 11, 2019

Excedrin (acetaminophen / aspirin / caffeine) for Osteoarthritis "Excedrin is the ONLY pill I have found that can take away the osteoarthritis pain in my lower back (doc says its lower back is disintegrating at my age 79. Also takes away aches and pains from muscles since I am heavy gardener. It has been the ONLY way I can stop headaches, and nearly all aches and pains. So grateful that it is on the market. It has saved me from a painful life."

10 / 10
Was this helpful?YesNo
22 Report
  • Mhenson...
  • Taken for 10 years or more
  • January 12, 2020

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I do not like the new packaging of on the go, I had no issues with old style, but do with new style, powder sticks inside has to be flicked and shaken to get out, also not sure you get as much as in old style but not sure about that part."

8 / 10
Was this helpful?YesNo
21 Report
  • New...
  • February 12, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Thought I was the only one experiencing issues w/the new packaging. After taking (opps excuse me "trying" to take it) I find myself opening it the SAME WAY as the old package was designed. The powder doesn't come out completely; it's super annoying. NOT a fan...at all...Even wrote the company directly, but no response. "If it ain't broke...""

5 / 10
Was this helpful?YesNo
24 Report
  • Not...
  • Taken for 10 years or more
  • July 26, 2013

Excedrin Migraine (acetaminophen / aspirin / caffeine) for Migraine "I can no longer take this medicine because it throws me into horrible anxiety attacks that mess with my blood pressure, make me dizzy, lightheaded and lethargic. Not to mention, an overall FEAR I am dying. These do get rid of the migraine for me but the effects are just not worth it. I used to be able to take it with no problem but not anymore. The anxiety, high blood pressure, and overall feeling of dying caused me to trash them so the temptation would not be there to subject myself to them anymore. I'm going to have to find another way of dealing with the headaches. Everyone is different, what their bodies can tolerate varies."

2 / 10
Was this helpful?YesNo
40 Report
  • Ricky
  • Taken for 2 to 5 years
  • August 26, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Love the Goody's Powder extra strength but I'm disliking these new power packets. The powder sticks to the package and in the corners. This new package was the worst thing the company could have ever done. Yes the new package allows you to carry individual packs with you but are more of a hassle to get the powder out of the package than it's worth. Bring back the original packets or sell both side by side and let the consumer decide. Contemplating finding a new over the counter headache medicine."

6 / 10
Was this helpful?YesNo
21 Report
  • Nick
  • May 3, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Will be looking for an alternative that has not gone to this type packaging. Goody's was my go-to for many years. The new packaging is beyond annoying. With the original paper, you could get the medicine on the back of the tongue - away from the bitter taste buds. As all the other reviews, powder gets stuck in the corner and goes all over your tongue. Not convenient, not broken, why mess it up?"

1 / 10
Was this helpful?YesNo
21 Report
  • mee
  • Taken for 10 years or more
  • April 10, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Powders don't seem to work as well as before, because you can not - I said can not get all the powder out of these NEW go-packs. They SUCK no one likes them, your sales will drop to nothing if you do not bring back the old package."

2 / 10
Was this helpful?YesNo
21 Report
  • annoyed
  • Taken for 10 years or more
  • March 28, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I have used Goodys for at least 30 years & have never found another product that works as good, UNTIL NOW. The new packaging is the most annoying thing ever & I agree with everyone else's comments that either the formula has changed or there isn't the same amount in the packs as before because 1 or 2 of them used to work great for headaches & now I can take them all day long & still have a headache. SOMETHING is different about them, other than the new annoying packs! Maybe a generic brand will come out & use the old packaging & will make a fortune!!!"

1 / 10
Was this helpful?YesNo
20 Report
  • RUE
  • Taken for 10 years or more
  • August 17, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I am so happy to see that I am not the only one that thinks this new packaging is a scam. Half the meds go in the trash. Waste of money. Waste of time. Even Dale Earnhardt jr as a sponsor. Just makes him look like a big fat liar. And so many in the south love and trust him. Huge disappointment!!!!!!!!!!!!!!!!!!!!!!! After 20 years of using Goodies. I will NEVER buy this product again. Advil will be my new love. At least with a tablet I know I am getting the whole med. Not just half."

5 / 10
Was this helpful?YesNo
18 Report
  • EranL...
  • Taken for 10 years or more
  • March 7, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I have been taking Goodys for 15+ years. They have been the only thing that has ever helped my headaches. When they introduced the new packaging I was happy because I thought it would be easier. Well, it's not and they don't work as good. My husband thought I was crazy until I stumbled upon this post. I have a box of the older powders in my car and I noticed today that it has SO much more powder and it actually worked. I'm so bummed :("

Was this helpful?YesNo
19 Report
  • Nan
  • Taken for 10 years or more
  • August 15, 2018

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Love Goody Powders .. It's a 10'. But, I hate the new packaging it's a ZERO. Please go back to the original. I've tried 4-5 different ways to open it and not successful getting into the groove with it. I have PsA arthritis and this packaging just doesn't work for me. I really hope you will consider your customers needs. PLEASE!! Go back to the foldout. Thank you(~.~)"

10 / 10
Was this helpful?YesNo
20 Report
  • Alabama
  • October 4, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I hope that the Prestige Brands Company gets their heads out of their . butts and changes back to the old packaging. I for one am searching for another product that is more user friendly. Listen to the users!"

8 / 10
Was this helpful?YesNo
17 Report
  • Kay
  • Taken for less than 1 month
  • December 25, 2018

Excedrin (acetaminophen / aspirin / caffeine) for Migraine "I had the worst experience taking Excedrin for the first time. I ended up in the hospital shortly after due to having a bad reaction to the caffeine in this medicine. My heart began racing and jumped to 130 bpm and kept rising. I began feeling faint and was rushed to the hospital. Although my migraine went away, it was not a pleasant experience. Be aware if you are sensitive to caffeine."

1 / 10
Was this helpful?YesNo
19 Report
  • XCust...
  • December 2, 2018

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "I have used Goodies for over 50 years and have loved the product. My wife is Chinese and we took a box with us to China one year. Her friends and family tried the product and went crazy for it. I literally had to send dozens of boxes as gifts when we returned to the states. Unfortunately, I guess all good things come to an end. I, like almost 100% of their loyal customers, can not stand the new packaging. It is impossible to get all of the medication out of the pack and I believe they have reduced the amount of the dosage as well. I think that they did it to make their product tamper-proof. A suggestion, if Goodies actually reads these reviews, would be to make the box itself tamper-proof and go back to the old sleeves that have worked for generations. Good Lord, don't you guys test these things before you dump something like this on your loyal customers. You have to know how bad this is and how dangerous it is going to be to your bottom line. WAKEUP GOODIES !"

10 / 10
Was this helpful?YesNo
18 Report
  • Missy
  • Taken for 10 years or more
  • August 14, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Packaging sucks! It sticks to the sides so you have to use more ( maybe that's the catch). It also gets wet from the sides of your mouth and clumps up. I have used this product for 20 years but this will be my last box."

2 / 10
Was this helpful?YesNo
16 Report
  • hexdude
  • October 1, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Agreed. I hate the new "Stick Packs." I think they call it that because the powder "sticks" in the pack. This is another example of some marketing department that has never actually used the product it promotes. When I am forced to buy these, I dump the powder into the old wraps and take those with me."

1 / 10
Was this helpful?YesNo
15 Report
  • Holli
  • Taken for 10 years or more
  • March 28, 2019

Goody's Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "First of all this has been the most effective powder medication I've have took . I wish you keep the regular packs because the new ones are not good . The taste has change , packs harden and difficult to open and get all the powder , plus it seems the dosage is not as strong . I prefer the regular and these days it getting harder to find them . How can I buy the older version ?"

3 / 10
Was this helpful?YesNo
16 Report
  • Turk
  • Taken for 10 years or more
  • August 19, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "The new packaging is horrible! Absolutely horrible! I have tried several methods to dispense the product, and there isn't a good way! Plus, I am not convinced it is the same formulation. PLEASE bring back the old packaging! Been using Goody's for 40 years, and I am about to stop as soon as I can't find the other."

10 / 10
Was this helpful?YesNo
15 Report
  • Turbo
  • July 21, 2019

Goody's Extra-Strength Headache Powders (acetaminophen / aspirin / caffeine) for Pain/Fever "Wait...I get it!..Goody’s are changing TO an ineffective, aggravating, irritating, less effective product that long time customers praise, in exchange for what some millennial jackass in advertising thinks is a good idea. Brilliant! After using Goody’s for five decades (they were 22 cents when I found them) I can only hope that this is a way they have devised to see how many users they actually have. Good work! Not! Say, ...an ad with the plethora of pissed off long-time customers storming the gates of Goody’s factory because their headache is killing them - may bring sales back up to pre-stupidity levels. If we wanted placebo headache relief, we would have been buying something else."

10 / 10
Was this helpful?YesNo
15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.