Yohimbine

Generic Name: yohimbine (yoh-HIM-bean)
Brand Name: Examples include Aphrodyne and Yocon

Yohimbine is used for:

Dilating the pupils of the eye or treating erectile dysfunction due to diabetes, blood vessel problems, or psychological reasons. It may also be used for other conditions as determined by your doctor.

Yohimbine is an alpha-blocker. It works by increasing certain chemicals in the body, which dilate the pupils of the eye. It also dilates blood vessels and increases blood flow in the penis, which helps to improve erectile function.

Do NOT use yohimbine if:

  • you are allergic to any ingredient in yohimbine
  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • you have heart problems, kidney problems, ulcers of the stomach or intestines, or a history of mental or mood disorders
  • you are taking medicines for mental or mood problems (eg, antidepressants, tranquilizers)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using yohimbine:

Some medical conditions may interact with yohimbine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems, kidney problems, high blood pressure, angina (chest pain), stomach or intestinal ulcers, or liver disease

Some MEDICINES MAY INTERACT with yohimbine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Medicines for mood or mental problems (eg, antidepressants, tranquilizers) because side effects may be increased by yohimbine

This may not be a complete list of all interactions that may occur. Ask your health care provider if yohimbine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use yohimbine:

Use yohimbine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Yohimbine may be taken with or without food.
  • It may take several weeks for yohimbine to work.
  • Do not exceed the recommended dose or take yohimbine for more than 10 weeks without checking with your doctor.
  • If you miss a dose of yohimbine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use yohimbine.

Important safety information:

  • Yohimbine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to yohimbine. Using yohimbine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Use yohimbine with extreme caution in the ELDERLY because they may be more sensitive to its effects.
  • Yohimbine is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Yohimbine is generally not recommended for use in women. Do not use yohimbine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if yohimbine is excreted in breast milk. Do not breast-feed while taking yohimbine.

Possible side effects of yohimbine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; flushing; headache; nausea; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; decreased or painful urination; fast heartbeat; hallucinations; irritability; panic attacks; restlessness; severe headache; sweating; tremors; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; excitation; fatigue; irritability; nervousness; paralysis; seizures; severe stomach upset; weakness.

Proper storage of yohimbine:

Store yohimbine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep yohimbine out of the reach of children and away from pets.

General information:

  • If you have any questions about yohimbine, please talk with your doctor, pharmacist, or other health care provider.
  • Yohimbine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take yohimbine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about yohimbine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to yohimbine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using yohimbine.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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