Yohimbine Side Effects
Some side effects of yohimbine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to yohimbine: oral tablet
If you experience any of the following serious side effects, stop taking yohimbine and seek emergency medical attention:
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a very irregular or fast heartbeat; or
confusion or unusual behavior.
Other, less serious side effects are more likely to occur. Continue to take yohimbine and talk to your doctor if you experience
anxiety, irritability, or nervousness;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to yohimbine: compounding powder, oral tablet
Nervous system side effects have included excitation, increased motor activity, tremor, and dizziness.
Cardiovascular side effects have included elevation in blood pressure and increase in heart rate.
Gastrointestinal side effects have included nausea and vomiting, commonly reported after parenteral administration of yohimbine.
Psychiatric side effects have included irritability and generalized anxiety.
General side effects have included headache and increase in sweating.
Dermatologic side effects have included skin flushing reported with oral administration.
A severe case of Raynaud's phenomenon has been reported in a 65-year-old man diagnosed with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia). Painful episodes which affected all toes and fingers and his penis lasted 10 to 15 minutes and were relieved with heat. Symptoms resolved slowly over time upon discontinuation of yohimbine. Upon rechallenge with yohimbine, the patient developed more severe Raynaud's phenomenon.
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