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Verapamil controlled-release tablets

Pronunciation

Generic Name: verapamil (ver-AP-a-mil)
Brand Name: Examples include Calan SR and Isoptin SR

Verapamil controlled-release tablets is used for:

Treating high blood pressure. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Verapamil controlled-release tablets is a calcium channel blocker. It works by relaxing (dilating) your blood vessels, which lowers blood pressure.

Do NOT use verapamil controlled-release tablets if:

  • you are allergic to any ingredient in verapamil controlled-release tablets
  • you have certain heart problems (eg, left ventricular dysfunction, sick sinus syndrome, second- or third-degree heart block and do not have a pacemaker), very low blood pressure, or moderate to severe congestive heart failure (CHF)
  • you have atrial fibrillation or flutter and a pre-excitation syndrome (extra conduction pathway in the heart), such as Wolff-Parkinson-White (WPW) syndrome or Lown-Ganong-Levine (LGL) syndrome
  • you have shock due to serious heart problems
  • you are taking dofetilide, or you have taken disopyramide within the past 48 hours

Contact your doctor or health care provider right away if any of these apply to you.

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Before using verapamil controlled-release tablets:

Some medical conditions may interact with verapamil controlled-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart failure or a recent heart attack with lung congestion, low blood pressure, or heart problems (eg, a very slow heart rate, heart block, heart valve disease)
  • if you have kidney or liver problems, muscular dystrophy, or a neuromuscular disease
  • if you are taking another blood pressure medicine or you are being treated for cancer

Some MEDICINES MAY INTERACT with verapamil controlled-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), clonidine, disopyramide, ketolides (eg, telithromycin), macrolides (eg, erythromycin), or ritonavir because they may increase the risk of verapamil controlled-release tablets's side effects
  • Phenobarbital, rifampin, or St. John's wort because they may decrease verapamil controlled-release tablets's effectiveness
  • Aldosterone blockers (eg, eplerenone), aspirin, carbamazepine, colchicine, cyclosporine, digoxin, dofetilide , doxorubicin,, dronedarone, eletriptan, erythromycin, everolimus, flecainide, HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), lithium, narcotic pain relievers (eg, fentanyl), paclitaxel, quinazolines (eg, terazosin), quinidine, ranolazine, theophyllines, or tolvaptan because the risk of their side effects may be increased by verapamil controlled-release tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if verapamil controlled-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use verapamil controlled-release tablets:

Use verapamil controlled-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take verapamil controlled-release tablets by mouth with or without food.
  • Check with your doctor before you eat grapefruit or drink grapefruit juice while you use verapamil controlled-release tablets.
  • Swallow verapamil controlled-release tablets whole. Do not crush or chew before swallowing.
  • Taking verapamil controlled-release tablets at the same time each day will help you remember to take it.
  • If you miss a dose of verapamil controlled-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use verapamil controlled-release tablets.

Important safety information:

  • Verapamil controlled-release tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use verapamil controlled-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using verapamil controlled-release tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Verapamil controlled-release tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Tell your doctor or dentist that you take verapamil controlled-release tablets before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including liver function, kidney function, complete blood cell counts, and blood pressure, may be performed while you use verapamil controlled-release tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use verapamil controlled-release tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Verapamil controlled-release tablets should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using verapamil controlled-release tablets while you are pregnant. Verapamil controlled-release tablets is found in breast milk. If you are or will be breast-feeding while you use verapamil controlled-release tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of verapamil controlled-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; fatigue; headache; lightheadedness; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; lightheadedness, especially when standing; severe dizziness; shortness of breath; swelling of the feet or hands; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, severe or persistent stomach pain, fever, general feeling of being unwell); unusually fast, slow, or irregular heartbeat.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased mental status; dizziness; loss of consciousness; seizures; shortness of breath; slow or irregular heartbeat.

Proper storage of verapamil controlled-release tablets:

Store verapamil controlled-release tablets between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep verapamil controlled-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about verapamil controlled-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Verapamil controlled-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take verapamil controlled-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about verapamil controlled-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to verapamil controlled-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using verapamil controlled-release tablets.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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