Ferumoxytol

Generic Name: ferumoxytol (FER-ue-MOX-i-tol)
Brand Name: Feraheme

Ferumoxytol is used for:

Treating anemia caused by low levels of iron in patients with chronic kidney disease.

Ferumoxytol is an iron replacement product. It works by replacing iron in the body.

Do NOT use ferumoxytol if:

  • you are allergic to any ingredient in ferumoxytol
  • you have high blood iron levels

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Prescription Drug Addiction - Are You at Risk?

Before using ferumoxytol:

Some medical conditions may interact with ferumoxytol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (including any iron preparations)
  • if you have low blood pressure or anemia that is not caused by low levels of iron
  • if you are on dialysis
  • if you will be having an MRI (magnetic resonance imaging)

Some MEDICINES MAY INTERACT with ferumoxytol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Oral iron supplements because their effectiveness may be decreased by ferumoxytol

This may not be a complete list of all interactions that may occur. Ask your health care provider if ferumoxytol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ferumoxytol:

Use ferumoxytol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Ferumoxytol is given as an injection at your doctor's office, hospital, or clinic. Ask your health care provider any questions you may have about how to use ferumoxytol.
  • Do not use ferumoxytol if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • If you miss a dose of ferumoxytol, contact your doctor right away.

Ask your health care provider any questions you may have about how to use ferumoxytol.

Important safety information:

  • Ferumoxytol may cause dizziness or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use ferumoxytol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Severe and sometimes fatal allergic reactions have occurred in patients using ferumoxytol. You will be observed for signs of an allergic reaction for at least 30 minutes after you receive ferumoxytol. Contact your doctor right away if you experience symptoms of an allergic reaction (eg, rash; hives; itching; fainting; trouble breathing; wheezing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness).
  • Ferumoxytol may interfere with certain lab tests, including MRIs and tests for iron in the blood. Be sure your doctor and lab personnel know you are using ferumoxytol.
  • Lab and/or medical tests, including blood iron levels, certain blood cell counts, and blood pressure, may be performed while you use ferumoxytol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Tell your doctor or dentist that you take ferumoxytol before you receive any medical or dental care, emergency care, or surgery.
  • Ferumoxytol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using ferumoxytol while you are pregnant. It is not known if ferumoxytol is found in breast milk. Do not breast-feed while using ferumoxytol.

Possible side effects of ferumoxytol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bluish skin or nails; chest, jaw, or left arm pain; fainting; fast or irregular heartbeat; loss of consciousness or unresponsiveness; numbness of an arm or leg; severe or persistent dizziness or light-headedness; shortness of breath; sudden, severe headache or vomiting; swelling at the injection site; swelling of the hands, ankles, legs, or feet; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of ferumoxytol:

Ferumoxytol is handled and stored by a health care provider. Keep ferumoxytol out of the reach of children and away from pets.

General information:

  • If you have any questions about ferumoxytol, please talk with your doctor, pharmacist, or other health care provider.
  • Ferumoxytol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take ferumoxytol or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ferumoxytol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ferumoxytol. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using ferumoxytol.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Hide
(web4)