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Ferumoxytol

Generic Name: ferumoxytol (FER-ue-MOX-i-tol)
Brand Name: Feraheme

Serious and sometimes fatal allergic reactions have happened with ferumoxytol. Allergic reactions have happened in people after the first dose and also in people who have received ferumoxytol before without a reaction. Early signs may include heart attack, low blood pressure, or passing out. The risk of an allergic reaction may be greater if you have allergies to many other medicines. Discuss any questions or concerns with your doctor.

You will be observed for at least 30 minutes after you receive ferumoxytol. This includes having your blood pressure and heart rate checked. Tell your doctor if you have bluish skin or nails; chest, jaw, or left arm pain; itching; rash; swelling of the tongue or throat; symptoms of low blood pressure (eg, dizziness or lightheadedness, fainting); trouble breathing; wheezing; or any other bad effects during or after the infusion.


Ferumoxytol is used for:

Treating anemia caused by low levels of iron in patients with chronic kidney disease.

Ferumoxytol is an iron replacement product. It works by replacing iron in the body.

Do NOT use ferumoxytol if:

  • you are allergic to any ingredient in ferumoxytol
  • you have high blood iron levels

Contact your doctor or health care provider right away if any of these apply to you.

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Before using ferumoxytol:

Some medical conditions may interact with ferumoxytol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (including any iron preparations)
  • if you have low blood pressure or anemia that is not caused by low levels of iron
  • if you are on dialysis
  • if you will be having an MRI (magnetic resonance imaging)

Some MEDICINES MAY INTERACT with ferumoxytol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Oral iron supplements because their effectiveness may be decreased by ferumoxytol

This may not be a complete list of all interactions that may occur. Ask your health care provider if ferumoxytol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ferumoxytol:

Use ferumoxytol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with ferumoxytol. Talk to your pharmacist if you have questions about this information.
  • Ferumoxytol is given as an infusion at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • If you miss a dose of ferumoxytol, call your doctor to find out what to do.

Ask your health care provider any questions you may have about how to use ferumoxytol.

Important safety information:

  • Tell your doctor or dentist that you take ferumoxytol before you receive any medical or dental care, emergency care, or surgery.
  • Ferumoxytol may interfere with MRIs for up to 3 months after the last dose. Ferumoxytol may also interfere with certain tests for iron in the blood. Be sure your doctor and lab personnel know you have received ferumoxytol.
  • Lab tests may be performed while you use ferumoxytol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use ferumoxytol with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using ferumoxytol while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while using ferumoxytol.

Possible side effects of ferumoxytol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); swelling of the hands, ankles, legs, or feet.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of ferumoxytol:

Ferumoxytol is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

General information:

  • If you have any questions about ferumoxytol, please talk with your doctor, pharmacist, or other health care provider.
  • Ferumoxytol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take ferumoxytol or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ferumoxytol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ferumoxytol. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using ferumoxytol.

Issue Date: June 3, 2015
Database Edition 15.2.1.003
Copyright © 2015 Clinical Drug Information, LLC

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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