Generic Name: citric acid/sodium citrate (SIH-trik AS-id/SOE-dee-um SIH-trayt)
Brand Name: Examples include Cytra-2 and Oracit
Citric acid/sodium citrate is used for:
Treating metabolic acidosis and certain kidney problems (eg, kidney stones). It may also be used for other conditions as determined by your doctor.
Citric acid/sodium citrate is an alkalinizing agent. It works by neutralizing excess acid in the blood and urine.
Do NOT use citric acid/sodium citrate if:
- you are allergic to any ingredient in citric acid/sodium citrate
- you have aluminum toxicity, untreated Addison disease, low or no urine production, high blood potassium, congestive heart failure, heart damage, or severe kidney problems, or if you are dehydrated
Contact your doctor or health care provider right away if any of these apply to you.
Before using citric acid/sodium citrate:
Some medical conditions may interact with citric acid/sodium citrate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are taking aluminum salts (eg, aluminum hydroxide), amphetamines or lithium
- if you have a history of kidney disease, heart disease, electrolyte/mineral imbalances (eg, high potassium levels), Addison disease, or stomach problems (eg, ulcer disease)
- if you have high blood pressure, a urinary tract infection, or toxemia, or you are on a sodium-restricted diet
Some MEDICINES MAY INTERACT with citric acid/sodium citrate. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aluminum salts (eg, aluminum hydroxide) because the risk of severe aluminum toxicity may be increased
- Anorexiants (eg, phentermine) or sympathomimetics (eg, pseudoephedrine) because side effects may be increased by citric acid/sodium citrate
- Lithium or tetracyclines (eg, doxycycline) because effectiveness may be decreased by citric acid/sodium citrate
This may not be a complete list of all interactions that may occur. Ask your health care provider if citric acid/sodium citrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use citric acid/sodium citrate:
Use citric acid/sodium citrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take citric acid/sodium citrate after meals and at bedtime, unless directed otherwise by your health care provider.
- Shake well before using.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Mix citric acid/sodium citrate with water before swallowing. Follow with additional water, if desired.
- If you miss a dose of citric acid/sodium citrate, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use citric acid/sodium citrate.
Important safety information:
- LAB TESTS, including blood electrolyte and bicarbonate levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- Use citric acid/sodium citrate with caution in CHILDREN younger than 2 years of age because they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking citric acid/sodium citrate, discuss with your doctor the benefits and risks of using citric acid/sodium citrate during pregnancy. It is unknown if citric acid/sodium citrate is excreted in breast milk. If you are or will be breast-feeding while you are using citric acid/sodium citrate, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of citric acid/sodium citrate:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; loose stools; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; confusion; severe stomach pain; tingling of hands or feet; vomit that looks like coffee grounds; weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; nausea; seizures; vomiting.Proper storage of citric acid/sodium citrate:
Store citric acid/sodium citrate at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not freeze. Keep citric acid/sodium citrate out of the reach of children and away from pets.
- If you have any questions about citric acid/sodium citrate, please talk with your doctor, pharmacist, or other health care provider.
- Citric acid/sodium citrate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take citric acid/sodium citrate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about citric acid/sodium citrate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to citric acid/sodium citrate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using citric acid/sodium citrate.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.