Centratex

Generic Name: ferrous fumarate/folic acid/b complex/vitamin c/minerals (FER-us FUE-ma-rate/FOE-lik AS-id/B KOM-pleks/VYE-ta-min C/MIN-er-als)
Brand Name: Centratex

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years of age. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.


Centratex is used for:

Treating anemia caused by low levels of iron or folate in the blood. It may also be used to treat other conditions as determined by your doctor.

Centratex is an iron, folic acid, vitamin, and mineral combination. It works by providing iron, folic acid, vitamins, and minerals when the body does not produce enough of its own.

Do NOT use Centratex if:

  • you are allergic to any ingredient in Centratex
  • you have iron metabolism problems (eg, hemosiderosis, hemochromatosis), certain types of anemia (pernicious, hemolytic), or high levels of iron in your blood
  • you have copper metabolism problems (Wilson disease)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Centratex:

Some medical conditions may interact with Centratex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach or bowel problems (eg, ulcer, bowel irritation or inflammation, Crohn disease)
  • if you have another type of anemia (eg, megaloblastic), a blood disorder (eg, thalassemia, porphyria), or if you have had multiple blood transfusions

Some MEDICINES MAY INTERACT with Centratex. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Fluorouracil because the risk of its side effects may be increased by Centratex
  • Doxycycline, hydantoins (eg, phenytoin), penicillamine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Centratex

This may not be a complete list of all interactions that may occur. Ask your health care provider if Centratex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Centratex:

Use Centratex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Centratex is absorbed better on an empty stomach, but may be taken with food if it upsets your stomach.
  • If you also take an antacid, bisphosphonate (eg, alendronate), cefdinir, eltrombopag, methyldopa, penicillamine, quinolone antibiotic (eg, levofloxacin), or tetracycline antibiotic (eg, minocycline), ask your doctor or pharmacist how to take it with Centratex.
  • Do NOT take Centratex within 1 hour before or 2 hours after eggs, whole grain breads or cereal, milk, milk products, coffee, or tea.
  • Take Centratex with a full glass of water (8 oz/240 mL).
  • If you miss a dose of Centratex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Centratex.

Important safety information:

  • Centratex has iron in it. Iron overdose is a leading cause of fatal poisoning in children younger than 6 years of age. In case of an overdose, call a doctor or poison control center right away.
  • Do not take more than the recommended dose without checking with your doctor.
  • Centratex has folic acid, iron, and zinc in it. Before you start any new medicine, check the label to see if it has folic acid, iron, or zinc in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do not take large doses of vitamins while you use Centratex unless your doctor tells you to.
  • While you are taking Centratex, you may notice a darkening of stools. This is normal.
  • Centratex may cause false test results with kits used to check for blood in the stool or blood cholesterol. Check with your doctor if you are using either kind of test kit.
  • Lab tests, including blood counts and blood iron levels, may be performed while you use Centratex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Centratex should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Centratex while you are pregnant. Centratex is found in breast milk. If you are or will be breast-feeding while you use Centratex, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Centratex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach discomfort.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; severe or persistent stomach pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org ), or emergency room immediately. Symptoms may include coma; fast or irregular heartbeat; fever; seizures; severe nausea; stomach pain; tarry stools; trouble breathing; unusual tiredness; or vomiting. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in CHILDREN younger than 6 years of age. Keep Centratex out of the reach of children.

Proper storage of Centratex:

Store Centratex at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Centratex out of the reach of children and away from pets.

General information:

  • If you have any questions about Centratex, please talk with your doctor, pharmacist, or other health care provider.
  • Centratex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Centratex. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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