Bontril PDM

Generic Name: phendimetrazine (FEN-dye-MET-ra-zeen)
Brand Name: Bontril PDM

Bontril PDM is used for:

The short-term management of obesity combined with a diet and exercise program.

Bontril PDM is an anorectic. Exactly how Bontril PDM works is unknown, although one of its effects is to decrease your appetite.

Do NOT use Bontril PDM if:

  • you are allergic to any ingredient in Bontril PDM or to a sympathomimetic medicine (eg pseudoephedrine)
  • you are pregnant or breast-feeding
  • you have glaucoma; an overactive thyroid; moderate, severe, or uncontrolled high blood pressure; or a history of drug abuse; or you are highly nervous or agitated
  • you have a history of stroke; high blood pressure in the lungs (pulmonary hypertension); uncontrolled high blood pressure; or heart problems (eg, heart blood vessel disease, heart failure, irregular heartbeat, heart murmur, heart valve problems)
  • you are taking another anorectic medicine (eg, phentermine), or if you have taken one within the past year
  • you are taking guanadrel or guanethidine, or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Bontril PDM:

Some medical conditions may interact with Bontril PDM. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems, diabetes, or high blood pressure
  • if you have had any type of unusual reaction to a sympathomimetic medicine (eg pseudoephedrine, albuterol)

Some MEDICINES MAY INTERACT with Bontril PDM. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Other anorectic medicines (eg, phentermine) because the risk of certain heart valve problems may be increased
  • Furazolidone or MAOIs (eg, phenelzine) because severe side effects, such as severe high blood pressure, irregular heartbeat, high fever, tremors, and seizures, may occur
  • Insulin or oral diabetes medicines (eg, glyburide) because the risk of low blood sugar may be increased
  • Guanadrel or guanethidine because their effectiveness may be decreased by Bontril PDM

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bontril PDM may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bontril PDM:

Use Bontril PDM as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Bontril PDM about 1 hour before meals. Take your last dose of the day at least 4 to 6 hours before bedtime, unless your doctor tells you otherwise.
  • If you miss a dose of Bontril PDM, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bontril PDM.

Important safety information:

  • Bontril PDM may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Bontril PDM with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol while you are taking Bontril PDM.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Some of these products may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.
  • Patients who take this type of medicine (anorectics) may have an increased risk of developing high blood pressure in the lungs. This condition is rare but often fatal. The risk may be higher in patients who take this type of medicine for longer than 3 months. It is not known if repeated treatment with this type of medicine may increase the risk. Discuss any questions or concerns with your doctor. Tell your doctor at once if you develop new or worsening shortness of breath, chest pain, fainting, or swelling of the legs or feet.
  • Heart valve problems have been reported in patients taking certain anorectic medicines. Discuss any questions or concerns with your doctor.
  • Diabetes patients - Bontril PDM may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Tell your doctor or dentist that you take Bontril PDM before you receive any medical or dental care, emergency care, or surgery.
  • Bontril PDM may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Bontril PDM.
  • Use Bontril PDM with caution in the ELDERLY; they may be more sensitive to its effects.
  • Bontril PDM should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Bontril PDM if you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if Bontril PDM is found in breast milk. Do not breast-feed while taking Bontril PDM.

After you have been taking Bontril PDM for a few weeks, it may not work as well as when you started to take it. This is known as TOLERANCE. Talk with your doctor if Bontril PDM stops working well. Do not take more than prescribed.

Some people who use Bontril PDM for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Bontril PDM suddenly, you may have WITHDRAWAL symptoms. These may include extreme tiredness or mental depression.

Possible side effects of Bontril PDM:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; dry mouth; flushing; headache; nausea; overstimulation; restlessness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; changes in sex drive; chest, jaw, or arm pain; fast or irregular heartbeat; frequent urination or trouble urinating; hallucinations; mental or mood changes; seizures; severe or persistent headache or dizziness; shortness of breath; stomach pain; sudden, severe nausea or vomiting; tremor; unusual sweating.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; confusion; diarrhea; fainting; fast or irregular heartbeat; hallucinations; mental or mood changes (eg, depression); nausea; panic attack; restlessness; seizures; severe dizziness or headache; stomach cramps; unusual tiredness; vomiting.

Proper storage of Bontril PDM:

Store Bontril PDM at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bontril PDM out of the reach of children and away from pets.

General information:

  • If you have any questions about Bontril PDM, please talk with your doctor, pharmacist, or other health care provider.
  • Bontril PDM is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Bontril PDM or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Bontril PDM. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Bontril PDM. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Bontril PDM.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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