Aralast NP

Generic Name: alpha-1 proteinase inhibitor (human) (AL-fa PROE-teen-ase in-HIB-i-ter)
Brand Name: Examples include Aralast NP and Zemaira

Aralast NP is used for:

Treating emphysema caused by alpha-1 proteinase inhibitor deficiency (also known as alpha-1 antitrypsin deficiency).

Aralast NP is an alpha-1 protease inhibitor. It works by blocking substances in the lungs that break down lung tissue and sometimes causes emphysema.

Do NOT use Aralast NP if:

  • you are allergic to any ingredient in Aralast NP
  • you have an immunoglobulin A (IgA) deficiency and have antibodies against IgA

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Aralast NP:

Some medical conditions may interact with Aralast NP. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart or circulatory problems

Some MEDICINES MAY INTERACT with Aralast NP. However, no specific interactions with Aralast NP are known at this time.

Ask your health care provider if Aralast NP may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Aralast NP:

Use Aralast NP as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Aralast NP is administered as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • Do not miss any doses. If you miss a dose of Aralast NP, contact your doctor.

Ask your health care provider any questions you may have about how to use Aralast NP.

Important safety information:

  • Tell your doctor or dentist that you take Aralast NP before you receive any medical or dental care, emergency care, or surgery.
  • Aralast NP contains albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used Aralast NP.
  • PREGNANCY and BREAST-FEEDING: It is not known if Aralast NP can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Aralast NP while you are pregnant. It is not known if Aralast NP is excreted in breast milk. If you are or will be breast-feeding while you use Aralast NP, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Aralast NP:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; muscle pain; nausea; pain, bruising, swelling, or redness at the injection site; runny nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; severe or persistent dizziness; shortness of breath or wheezing; swelling of the ankles or feet; symptoms of infection (eg, fever, chills, muscle aches, sore throat); tingling or numbness of the skin; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Aralast NP:

Aralast NP is handled and stored by a health care provider. You will not store it at home. Keep all medicines, as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about Aralast NP, please talk with your doctor, pharmacist, or other health care provider.
  • Aralast NP is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Aralast NP or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Aralast NP. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Aralast NP. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Aralast NP.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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