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Anidulafungin

Generic Name: anidulafungin (ay-NID-ue-la-FUN-jin)
Brand Name: Eraxis

Anidulafungin is used for:

Treating certain types of fungal infections.

Anidulafungin is an echinocandin antifungal. It works by killing sensitive fungi.

Do NOT use anidulafungin if:

  • you are allergic to any ingredient in anidulafungin or to another echinocandin antifungal (eg, caspofungin)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using anidulafungin:

Some medical conditions may interact with anidulafungin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver problems or abnormal liver function tests

Some MEDICINES MAY INTERACT with anidulafungin. However, no specific interactions with anidulafungin are known at this time.

Ask your health care provider if anidulafungin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use anidulafungin:

Use anidulafungin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Anidulafungin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using anidulafungin at home, a health care provider will teach you how to use it. Be sure you understand how to use anidulafungin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use anidulafungin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • To clear up your infection completely, use anidulafungin for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of anidulafungin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use anidulafungin.

Important safety information:

  • Anidulafungin may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use anidulafungin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Anidulafungin only works against fungi; it does not treat viral infections (eg, the common cold) or bacterial infections.
  • Be sure to use anidulafungin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Tell your doctor or dentist that you take anidulafungin before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Anidulafungin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including liver function, may be performed while you use anidulafungin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Anidulafungin should be used with extreme caution in CHILDREN younger than 17 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using anidulafungin while you are pregnant. It is not known if anidulafungin is found in breast milk. If you are or will be breast-feeding while you use anidulafungin, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of anidulafungin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; headache; indigestion; mild stomach pain; nausea; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; confusion; depression; difficult or painful urination; fainting; fever, chills, cough, or persistent sore throat; flushing; irregular heartbeat; leg or calf redness, swelling, or pain; muscle pain, weakness, or cramping; pain, swelling, or redness at the injection site; seizures; severe or persistent dizziness or headache; shortness of breath; swelling of the hands, ankles, or feet; symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, severe stomach pain, yellowing of the skin or eyes); unusual bruising or bleeding; unusual tiredness or weakness; vision problems (eg, blurred vision); wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of anidulafungin:

Anidulafungin is usually handled and stored by a health care provider. If you are using anidulafungin at home, store anidulafungin as directed by your pharmacist or health care provider. Keep anidulafungin out of the reach of children and away from pets.

General information:

  • If you have any questions about anidulafungin, please talk with your doctor, pharmacist, or other health care provider.
  • Anidulafungin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take anidulafungin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about anidulafungin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to anidulafungin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using anidulafungin.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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