Anidulafungin Side Effects

Brand Names: Eraxis

Please note - some side effects for Anidulafungin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Anidulafungin - for the Consumer

Anidulafungin

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Anidulafungin:

Diarrhea; headache; pain, swelling, or redness at the injection site.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); dark urine; fever, chills, or persistent sore throat; irregular heartbeat; leg redness, swelling, or pain; pale stools; seizures; severe or persistent stomach pain; shortness of breath; unusual bruising or bleeding; yellowing of the skin or eyes.

Side Effects by Body System

General

Possible histamine-mediated symptoms have been reported, including rash, urticaria, flushing, pruritus, dyspnea, and hypotension. These events are infrequent when the rate of infusion does not exceed 1.1 mg/minute. Other general effects have included pyrexia, peripheral edema, and rigors.

Gastrointestinal

Gastrointestinal side effects have included diarrhea (3.1%) and nausea (1%). Other, less common gastrointestinal effects have included dyspepsia, vomiting, upper abdominal pain, constipation, and fecal incontinence.

Hepatic

Hepatic side effects have included elevated liver enzymes (less than 3%), cholestasis, and hepatic necrosis.

Metabolic

Metabolic side effects have included hypokalemia (3.1%), hypercalcemia, hyperglycemia, hypernatremia, hyperkalemia, and hypomagnesemia.

Nervous system

Nervous system side effects have included headache (1.3%), convulsion, and dizziness.

Hematologic

Hematologic side effects have included neutropenia (1%), leukopenia, coagulopathy, and thrombocytopenia.

Dermatologic

Dermatologic side effects have included rash (1%), erythema, increased sweating, and angioneurotic edema.

Cardiovascular

Cardiovascular side effects have rarely included deep vein thrombosis, phlebitis, atrial fibrillation, bundle branch block (right), sinus arrhythmia, ventricular extrasystoles, flushing, hot flushes, hypertension, hypotension, and thrombophlebitis.

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