Generic Name: adapalene (ADE-ah-PAH-leen)
Brand Name: Differin
Adapalene solution is used for:
Treating acne. It may also be used for other conditions as determined by your doctor.
Adapalene solution is a retinoid-like medicine. It works by decreasing acne formation.
Do NOT use adapalene solution if:
- you are allergic to any ingredient in adapalene solution
Contact your doctor or health care provider right away if any of these apply to you.
Before using adapalene solution:
Some medical conditions may interact with adapalene solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have eczema or sunburn
Some MEDICINES MAY INTERACT with adapalene solution. Because little, if any, of adapalene solution is absorbed into the blood, the risk of it interacting with another medicine is low.
Ask your health care provider if adapalene solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use adapalene solution:
Use adapalene solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Adapalene solution is for external use only. Avoid contact with the eyes, lips, angles of the nose, and mouth. Exposure of adapalene solution to the eye may cause swelling, redness, and irritation.
- Do not apply adapalene solution to cuts, abrasions, eczema, or sunburned skin. If you are sunburned, do not use this product on the sunburned area until your skin has completely recovered.
- Before applying adapalene solution, clean the area to be treated with mild soap or soapless cleanser and gently dry.
- Apply a thin film of adapalene solution to the affected area using enough to lightly cover the entire area. Rub in gently. Wash your hands immediately after using adapalene solution.
- If you miss a dose of adapalene solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use adapalene solution.
Important safety information:
- Adapalene solution may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to adapalene solution. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Acne may worsen in the early stages of taking adapalene solution. This is due to the action of adapalene solution on unseen lesions. It may take 8 to 12 weeks before you see the full benefit.
- Talk with your doctor before you use any other medicines or cleansers on your skin.
- Wind and cold temperatures may irritate the affected skin.
- Adapalene solution should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using adapalene solution while you are pregnant. It is not known if adapalene solution is found in breast milk. If you are or will be breast-feeding while you use adapalene solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of adapalene solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Acne; dry skin; feeling of warmth; irritation; itching; peeling; redness; scaling; sunburn; temporary burning or stinging.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistering; crusting; excessive redness or peeling; swelling.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of adapalene solution:
Store adapalene solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep bottle tightly closed and store upright. Do not store in the bathroom. Keep adapalene solution out of the reach of children and away from pets.
- If you have any questions about adapalene solution, please talk with your doctor, pharmacist, or other health care provider.
- Adapalene solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about adapalene solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.