No published information is available on the use of zileuton during breastfeeding; however, manufacturer's data indicate that the dose in milk is low. An expert guideline considers that leukotriene receptor antagonists can be used during breastfeeding.[1]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Bendien SA, de Kruif MD, Feitsma H, et al. Summary of the Dutch Multidisciplinary Practice Guideline on Asthma and Pregnancy. J Allergy Clin Immunol Pract 2024;12:1751-62 [PubMed: 38513758]
Substance Identification
Substance Name
Zileuton
CAS Registry Number
111406-87-2
Drug Class
Breast Feeding
Lactation
Milk, Human
Anti-Asthmatic Agents
Leukotriene Antagonists
Lipoxygenase Inhibitors
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