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Dextromethorphan use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on May 1, 2024.

Drugs containing Dextromethorphan: Auvelity, Promethazine DM, Bromfed DM, Mucinex DM, Delsym, Vicks NyQuil Cold & Flu Nighttime Relief, Robitussin Cough + Chest Congestion DM, Vicks DayQuil Severe Cold & Flu, Delsym 12 Hour Cough Relief, Nuedexta, Show all 1031 »Vicks NyQuil Severe Cold & Flu, Vicks Dayquil Cold & Flu Relief, Tylenol Cold & Flu Severe, Mucinex DM Maximum Strength, Tussin DM, Dexcon-DM, Cough & Cold Relief, Mucinex Fast-Max Severe Cold, Coricidin HBP Cough & Cold, Robitussin Cough & Cold D, Promethazine with Dextromethorphan, Dimetapp Children's Cold & Cough, Coricidin HBP Chest Congestion & Cough, Polytussin DM, Strepsils Cough, Vicks Dayquil Cough, Robitussin Nighttime Cough DM, Mucinex Fast-Max Cold, Flu & Sore Throat, Mucinex Nightshift Cold & Flu, Vicks Nyquil Cough, Resperal-DM, Coricidin HBP Maximum Strength Flu, Alka-Seltzer Plus Severe Cold & Flu Day & Night (Night Formula), Mucus Relief DM, Capmist DM, Robitussin Allergy & Cough, Dry Cough, Deconex DMX, Vicks Children’s NyQuil Cold & Cough, Mucinex Children's Cough, Tusnel, Capron DM, Comtrex Cold and Flu Maximum Strength Tablet, Vicks Nyquil D Cold and Flu Nighttime Relief, Mucinex Fast-Max Severe Congestion & Cold, Vicks Dayquil Daytime Cold/Flu (old formulation), Rynex DM, M-End DMX, Giltuss, Alahist DM, Tylenol Cold, Tylenol Cold & Cough Daytime, Robitussin Cold Cough and Flu, Buckley's Mixture Cough Suppressant, DexAlone, Robitussin Multi-Symptom Cold CF, Capron DMT, Robitussin Severe Multi-Symptom Cough Cold + Flu, Theraflu Warming Relief Daytime Severe Cold & Cough, Alahist CF, WesTussin DM, Vicks Formula 44, Dextromethorphan HBr Adult Formula, Mucinex Cough & Chest Congestion, Guaifenesin DM, Tussin DM Max, Theraflu Flu & Cough, Theraflu Daytime Severe Cold & Cough, Robitussin Cough & Allergy, Covonia Bronchial Balsam, Cough Syrup DM, Vicks Nyquil Cough DM + Congestion, Delsym Cough+ Chest Congestion DM, Mucinex Fast-Max Severe Congestion & Cough, Dexcon-PE, Mucinex Children's Multi-Symptom Cold, Histex-DM, Phenergan with Dextromethorphan, XL-3 Xtra Cold and Cough, Delsym Cough & Sore Throat, Diabetic Tussin Night Time Formula, Night Time Cold & Flu, Duraflu, Sudafed PE Pressure+Pain+Cough, AccuHist PDX Syrup, Neotuss D, NoHist DM, Ed A-Hist DM, Resperal, Benylin DM, Bisolvon Dry, Creomulsion, Benylin Expectorant, Trispec PSE, Poly Hist DM, Promethazine with DM, Vicks NyQuil Cold & Flu Nighttime Relief (Alcohol Free), Tylenol Children’s Cold + Cough + Runny Nose, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Codral Cold and Flu + Cough Day and Night, Alka-Seltzer Plus Severe Cold & Flu Formula Effervescent Tablets, Alka-Seltzer Plus-D Multi-Symptom Sinus & Cold Liquid Gels, Tylenol Children’s Cold + Cough + Sore Throat, Coricidin HBP Nighttime Multi-Symptom Cold, Sudafed PE Cold & Cough, Mucinex Sinus-Max Pressure, Pain & Cough, Adult Cold, Flu & Sore Throat, Neocitran Non Drowsy Extra Strength Cold and Flu, Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels, Mucinex Nightshift Severe Cold and Flu, Mucinex Children's FreeFrom Multi-Symptom Cold & Flu Nighttime, Tylenol Cold + Flu Multi-Action, BP Allergy DM, DM Cold and Cough, Dimetane DX, Gencontuss, Vicks Formula 44 Custom Care Dry Cough Suppressant, Strepsils Cough Relief, Delsym Children's 12-Hour Cough Relief, Buckleys Mixture, Robitussin CoughGels Long-Acting, St. Joseph Cough Suppressant, Humibid CS, Mucinex Fast-Max DM Max, G-Zyncof, Safetussin DM, Zyncof, Vicks DayQuil Cough & Congestion, Robitussin Children's Cough & Cold CF, Tusicof, Phlemex Forte, Tussin CF, Giltuss Cough & Cold, Tussin Cough and Cold, Theraflu Cold & Cough, Decongestant Cold Formula, Endal Liquid, Coricidin HBP Day & Night Multi-Symptom Cold, Tylenol Children’s Cold + Flu, Tylenol Cold Multi-Symptom Nighttime, Childrens Tylenol Cold Plus Cough, Children's Triacting, Tylenol Cold Multi-Symptom Nighttime Liquid, Tylenol Severe Cold & Flu Night Time, Mucinex Children's Cold, Cough & Sore Throat, Sudafed PE Head Congestion + Flu Severe, Mucinex Fast-Max Cold, Flu & Sore Throat Liquid Gels, CounterAct Day, Cold Head Congestion, Cold & Cough PE Multi-Symptom, Theraflu Max-D Severe Cold & Flu, Daytime Cold & Flu, Mucinex Fast-Max Congestion & Headache, Flu & Severe Cold & Cough Daytime Powder, Daytime Cold and Flu Relief, Theraflu (pseudoephedrine) Daytime Severe Cold, Alka-Seltzer Plus Cold and Cough Powerfast Fizz, Alka-Seltzer Plus Severe Cold Powerfast Fizz Day and Night, Dimaphen DM, Cold & Cough Childrens, Poly DM, Myphetane DX, Brometane DX, DMax, DMax Syrup, Carbodex DM Drops, Dynatuss, Triaminic Night Time Cough & Runny Nose, NeoTuss Plus, Trital DM, Tricodene Forte, Children's Nyquil, TanaCof DM, Tanafed DMX, Pertussin DM, Bisolvon Dry Junior, Buckley's DM, Hold, Robitussin Nighttime Cough DM Maximum Strength, Robafen DM, Cough Formula-DM, Guaiasorb Cough Medicine, Vicks Formula 44 Custom Care Chesty Cough, Duratuss DM, Ru-Tuss 800 DM, Siltussin DM, Tussin Cough, Creo-Terpin, Refenesen Chest Congestion Relief DM, Chest Congestion Relief DM, Coricidin HBP Multi-Symptom Cold (Day), Guiatuss DM, Vicks Pediatric Formula 44e Cough & Chest Congestion Relief, Mucinex Children's Congestion & Cough, Despec DM Syrup, Guaphen Forte, DuraMAX, Giltuss TR, Desgen DM, Zotex-EX, Robitussin CF, Despec DM, Mucinex Instasoothe Sore Throat + Cough Relief, Triaminic Multi-Symptom Fever, PediaCare Cough & Runny Nose Plus Acetaminophen, Flu HBP Maximum Strength, Mapap Cough & Sinus Formula, Vicks Formula 44 Custom Care Cough & Cold PM, Flu Relief BP, Coricidin HBP Multi-Symptom Cold (Night), Tylenol Cold and Flu Severe Day & Night, Dimetapp Children's Multi-Symptom Cold & Flu (old formulation), PediaCare Multi-Symptom Cold Plus Acetaminophen, PediaCare Flu Plus Acetaminophen, Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerFast Fizz, Tylenol Cold Head Congestion Nighttime, Comtrex Cold & Cough Day Night, Theraflu Nighttime Severe Cold & Cough Caplets, Tylenol Cold Head Congestion Day and Night, Comtrex Nighttime Cold & Cough, Alka-Seltzer Plus Maximum Strength Cold & Cough, Cold Multi-Symptom (Nighttime), Multi Symptom Cold (Night Formula), Multi Symptom Cold Relief, Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid Gels, Alka-Seltzer Plus Severe Sinus & Cold Hot Drink Mix, Dimetapp Children's Nighttime Flu, Theraflu Warming Relief Nighttime Multi-Symptom Cold Caplets, Triaminic Multi-Symptom Fever & Cold, Giltuss Multi-Symptom Cold & Flu, Giltuss Children's Multi-Symptom Cold & Flu, Comtrex Cold and Flu Maximum Strength, Comtrex Maximum Strength Cold Relief, Contac Severe Cold and Flu Maximum Stength, Theraflu Flu, Cold and Cough Powder, Comtrex Day and Night, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Contac Cold and Flu Maximum Strength, Allpanto-S, Co-Apap, Theracaps Multi-Symptom Cough & Cold Reliever, Triaminic Flu, Cough & Fever, PediaCare Cough & Sore Throat Plus Acetaminophen, Triaminic Cough & Sore Throat, Drixoral Cough/Sore Throat, Tylenol Cough and Sore Throat Daytime, Triaminic Softchews Cough & Sore Throat, Topcare Cough and Sore Throat, Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Daytime, Vicks DayQuil HBP Cold & Flu, Diabetic Tussin Night Time Cold & Flu, Mucinex Fast-Max Day Time Severe Cold and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough and Night Time Cold & Flu Maximum Strength, Mucinex Children's Day Time & Night Time Multi-Symptom Cold Value Pack, Respa C&C, Respa C&C IR, Contac Day and Night Cold and Flu, Robitussin Peak Cold Nighttime Cold + Flu, Contac Cold + Flu (Night) Cooling Relief Liquid, Delsym Night Time Cough & Cold, Robitussin Cold + Flu (Nighttime), Vicks Nature Fusion Cold & Flu Nighttime Relief, Tylenol Cold & Cough Nighttime, Multi Symptom NiteTime, Night Time Multi Symptom Cold/Flu Relief, Alka-Seltzer Plus Severe Cold+Cough Night Liquid, Tylenol Cough & Sore Throat Nightime, Vicks NyQuil HBP Cold & Flu, Clear Cough PM Multi-Symptom, Mucinex Fast-Max Day & Night, Mucinex Sinus-Max Day & Night, DayQuil/NyQuil Severe Cold and Flu, Mucinex Fast-Max Day Severe Cold and Night Cold & Flu, Delsym Night Time Multi-Symptom, Alka-Seltzer Plus Night Cold Formula Liquid, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Night Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough (Night Formula), Mucinex Fast-Max Night Time Cold & Flu Liquid Gels, Alka-Seltzer Plus Severe Sinus Congestion, Allergy & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Night Cold & Flu Liquid Gels, Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula), Alka-Seltzer Plus Multi-Symptom Cold & Flu Day & Night Liquid Gels (Night Formula), Alka-Seltzer Plus Night Severe Cold+Flu Hot Drink Mix, All-Nite Cold, Multi-Symptom Nighttime, NyCair, All-Nite Multi-Symptom Cold/Flu Relief, Coricidin HBP Cold Cough and Flu Maximum Strength, Mucinex Sinus-Max Pressure, Pain & Cough and Sinus-Max Clear & Cool Nasal Spray, Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Children's FreeFrom Multi-Symptom Cold, Flu & Sore Throat, Delsym Cough+ Cold Day Time, Mucinex Fast-Max Day Time Severe Cold, Tylenol Cold Multi-Symptom Severe, Non-Pseudo Cold Relief, Tylenol Cold + Mucus Severe, Tylenol Cold Head Congestion Severe (old formulation), Decorel Forte Plus, Alka-Seltzer Plus Severe Cough, Mucus & Congestion Liquid Gels, Alka-Seltzer Plus Severe Sinus, Cold & Cough Liquid Gels, Phenflu DM, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Day Severe Cold+Flu Hot Drink Mix, Rompe Pecho MAX, Cold Multi-Symptom Severe, ConRx Cold, Mucus Relief Complete, Mucus Relief Plus, Suphedrine PE Cold & Cough, Sudafed PE Pressure+Pain+Cold, Tylenol Cough & Severe Congestion Daytime, Mucinex FreeFrom Cold & Flu Daytime and FreeFrom Cold & Flu Nighttime, Mucinex Fast-Max Severe Congestion & Cough and Nightshift Cold & Flu, Anatuss, Tylenol Cold Severe Congestion Daytime, Phlemgesic, Balminil Cough and Flu Sugar Free, Flutabs, Maxiflu DM, Tusnel-A, Mucinex Fast-Max DM Max and Nightshift Cold & Flu, Mucinex Fast-Max DM Max & Mucinex Nightshift Cold & Flu, Robitussin Peak Cold Daytime Cold + Flu, Contac Complete Cough, Cold & Flu Extra Strength, Tylenol Plus Children's Cold & Cough, Robitussin Cold + Flu (Daytime), Comtrex Cold & Cough, Mapap Cold Formula, BC Cough & Cold, Little Colds Multi-Symptom, Vicks Nature Fusion Cold & Flu Multi-Symptom Relief, Comtrex Cold and Cough Maximum Strength, Day Relief PE, Vicks Dayquil Cold & Flu Symptom Relief Plus Vitamin C, Day Time Multi-Symptom Cold/Flu Relief, Multi Symptom Cold (Day Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu Day Liquid Gels, Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Cold Multi-Symptom (Daytime), Theraflu Warming Relief Daytime Multi-Symptom Cold Caplets, Tylenol Cold Max Day, Tylenol Cold Head Congestion Daytime, Theraflu ExpressMax Daytime Severe Cold & Cough, Mucinex Nightshift Sinus, Mucinex Nightshift Cold & Flu Clear & Cool, Mucinex Nightshift Sinus Clear & Cool, Comtrex Non Drowsy Liquigel, Theraflu Flu Cold & Cough, Alka-Seltzer Plus Flu/Body, Comtrex Non-Drowsy, Contac Severe Cold and Flu Non Drowsy, Day Time Multi Symptom, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Daytime Non-Drowsy, Severe Cold Multi-Symptom, Daytime Cold, Quelidrine, Alka-Seltzer Plus Flu Formula (old formulation), Alka-Seltzer Plus Cold & Cough Formula Effervescent Tablets, Alka-Seltzer Plus Day & Night Cold Formula (Night Cold), Alka-Seltzer Plus Cold Powerfast Fizz Night, Alka-Seltzer Plus Night Cold Formula Effervescent Tablets, Alka-Seltzer Plus Day & Night Cold Formula (Day Cold), Alka-Seltzer Plus Non-Drowsy Cold Effervescent Tablets, Cepacol Extra Strength Sore Throat & Cough, Cough-X, Cepacol Dual Relief Sore Throat + Cough Spray, Cepacol Sore Throat + Cough Relief, Spec-T Sore Throat/Cough Suppressant, Cough-X Cough Relief, Chloraseptic Total Sore Throat+Cough Lozenges, Cepastat Sore Throat & Cough, Uni-Hist PDX Syrup, Allanhist PDX Syrup, EndaCof-PD, Bromhist-PDX, Acutuss DM Pediatric, Uni-Hist DM Pediatric Syrup, AccuHist DM Pediatric Syrup, Bromhist-DM, Pediahist DM Syrup, Histacol DM Pediatric Syrup, Niva-Hist DM, Alahist DM (old formulation), BroveX PB DM, BPM DM PHEN, Duravent DPB, Alacol DM, Presgen B, Y-COF DMX, TL-Hist DM, Tusdec-DM, Bromtuss DM, Dur-Tann DM, Tussi-Pres B, BroveX PEB DM, BPM PE DM, LoHist PEB DM, Dimetapp Children's Multi-Symptom Cold Relief Dye-Free, Balacall DM, Brotapp PE-DM, Lohist-DM, Glenmax PEB DM, Bromatan-DM, Glenmax PEB DM Forte, DuraTan DM, EndaCof-DM, AP-Hist DM, M-Hist DM, Relcof DM, Histinex DM, Prohistine DM, Highland DM, Delhistine DM, Polytine DM, Iohist DM, KG Hist DM, Uni Multihist DM, Liquihistine DM, Trihist DM, Poly Histine DM, Durahistine DM, Dimetapp DM, EndaCof PD Drops, AccuHist DM Pediatric Drops, PediaHist DM, BroveX PSE DM Tablets, BroveX PSE DM, PBM Allergy, BroveX PSB DM, Anaplex DMX, BromTann/DM Tann/PSE Tann, Bromdex D, Neo DM Syrup, Dallergy DM, Bromanate DX Cough, Bromatane DX, Myphetane DX Cough, Bromophed-DX, Liquiphed DM, Bromadine-DM, Anaplex DM, Bromphenex DM, Brotapp-DM, Andehist DM NR Syrup, Bromtapp-DM, Bromaxefed DM RF Syrup, PSE Brom DM, Bromaline DM, Carbofed DM Syrup, Uni-Hist DM Pediatric Drops, Bromplex DM, Bromhist-DM Drops, Pediahist DM Drops, Q-Tapp DM, Bromph DM, Uni-Hist PDX Drops, Allanhist PDX Drops, Histacol BD Drops, Brom Tann, ProHist DM, P-Hist DM Drops, Carbodex DM Syrup, Sildec DM, TriTuss-A Drops, Dacex-A, XiraHistDM, X-Hist DM, DMax Pediatric Drops, DMax Pediatric, Trituss-A, Andehist DM NR, Cordron-DM, Tussafed, Biodec DM, Rondamine DM, Maldec-DM, Cydec-DM Syrup, Dura-Ron DM, Cydec-DM Drops, Carbaxef-DM, Carbofed DM Drops, Decahist-DM, Pediatex-DM, Cordron-DM NR, Pseudo Carb DM, Mintex DM, PSE Carbinoxamine DM, PSE Carb DM Drops, Carboxine DM, Carboxine 12 DM, Carb PSE 12 DM, PSE Allergy DM, Cordron-12 DM, Pediatex 12 DM, QC Cough/Cold, Effective Strength Cough Syrup, Primatuss 4, Tricodene Sugar Free, Triaminic Softchews Cough & Runny Nose, Dimetapp Children's Long Acting Cough Plus Cold, Robitussin Children's Cough & Cold Long-Acting, Robitussin Cough & Cold Long-Acting, Carepanto, Scot-Tussin DM, St. Joseph HBP Cough & Cold, Robitussin Children's Nighttime Cough Long-Acting DM, SymPak DM, Broncopectol, ChlorDex GP, Qual-Tussin, Quartuss, Genelan NF, Zotex-DM, Extendryl DM, Rondec-DM, Donatussin DM, Ceron-DM Drops, Ceron-DM, Rondex-DM, Rondex-DM Drops, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, HistadecDM, CP Dec DM, Neo DM Drops, Nasohist-DM Pediatric, Cardec DM Drops, Balamine DM, Reme Tussin DM, Tussplex DM, Norel CS, Cardec DM, C-Phen DM, C-Phen DM Drops, Sildec-PE DM Drops, Sildec-PE DM, DCP Drops, EndaCof Drops, PE-Hist DM, Maxichlor PEH DM, ED DM, Poly-Tussin DM, Ricotuss, Tri-Dex PE, Z-Dex 12 D, Trigofen DM Drops, Virdec DM, Zoden DM Drops, Phenabid DM, Re DCP, Sonahist-DM, RE DCP Drops, Nohist-DMX, Bronkids, Donatussin DM Drops, Nasohist-DM, DM-PE-Chlor, CP Dec-DM Drops, PD-Cof Drops, PD-Cof, Zotex-12D, Quartuss DM, Statuss DM, Giltuss Allergy Plus, NoHist-PDX, Relahist-DM, Albatussin SR, Cerose DM, Maxiphen ADT, Tussar DM, Liquituss R-DM, Centergy DM, Atuss DM, Father John's Medicine Plus, Norel DM, De-Chlor DM, De-Chlor DR, Coldtuss-DR, Tri-Vent DPC, Giltuss Allergy Plus Cough & Congestion, Atuss DR, Giltuss Children's Allergy Plus Cough & Congestion, Corfen-DM, Uni-Tuss DM, Mintuss DR, P Chlor DM, Dex PC, Tricodene NN, Cheracol Plus, Therahist, Triphenicol, Kophane, Threamine DM, Rhinosyn-DM, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Creomulsion Pediatric, Kidcare Cough and Cold, Rescon-DM, Tanafed-DM, C-Phed DM, M-End DM, Atuss-12 DM, Dicel DM, Atuss DS, Entre-S, Maxichlor PSE DM, Kidkare Cough/Cold, Neutrahist PDX Drops, AccuHist PDX Drops, CPM-PSE DM Drops, Esocor P, Mesehist DM, Triaminic-D Multi-Symptom Cold, Allres DS, Duotan DM, T-Tanna DM, Pedia Relief Cough-Cold, Deka, Dexall, Bionatuss DXP, Panatuss Pediatric DXP, G-P-Tuss DXP, Y-Cof DM, Supress A, Panatuss DXP, Tussall, Tussall-ER, Supress A Pediatric, Poly Tan DM, Donatussin DM Suspension, Coryza-DM, ProHist, P-Hist, Tannate DMP-DEX, C-Phed DPD Tann, DuraTan Forte, Bromatan Plus, Dur-Tann Forte, TanDur DM, SuTan-DM, Tannate PD-DM, Deltuss DMX, Abatuss DMX, Babee Cof, Silphen DM, Balminil DM, Delsym 12 Hour Cough Relief for Children & Adults, Calmylin, Novahistine DM, Robitussin Cough Long-Acting, Triaminic Thin Strips Long Acting Cough, Benadryl for the Family Dry Forte, Theraflu Thin Strips Cough, Neocitran Thin Strips Cough, Contac Cough, Robafen Cough Liquidgels, Jack & Jill Thin Strips Cough, Tussinol for Dry Coughs, Dristan DM, Dexi-Tuss, Nucosef DM, Sucrets Cough, Pedia Relief, Triaminic Long Acting Cough, Creomulsion Children, Robitussin Direct Cough, Tussin Cough Gels (Long Acting), Vicks Nature Fusion Cough, Duract Max Strength Cough, Scot-Tussin Diabetes, Lloydspharmacy Dry Adult Cough, 12 Hour Cough Relief, Triaminic Thin Strips Cough, Robitussin 12-Hour Cough Relief, Giltuss Honey DM 8hr Cough, Giltuss Children's Honey DM 8hr Cough, ElixSure Cough, Scot-Tussin DM Cough Chasers, Hold DM, Pertussin CS Childrens, Robitussin Children's Cough Long-Acting, Pertussin ES, PediaCare Children's Long-Acting Cough, Tussin Pediatric, Robafen Pediatric Cough & Cold, Dytan-DM, Duratuss AC 12, D-Tann DM, Nighttime Cough, Safetussin PM, Lortuss DM, Mastussin DM, Recofen D, Recofen Plus, Ri-Tussin DM, Robichem DM, T-Tussin DM, Tusscidin DM, Bidex-DMI, Vicks DayQuil Mucus Control DM, GG-DM SR, Humigen DM, Tussidin DM, Altarussin DM, Guiat Clear DM, Kita La Tos, Q-Tussin DM, Bidex-DM, Nalspan Senior DX, Diabetic Tuss DM, Scot-Tussin Senior, Naldecon DX Liquigel, Safetussin 30 DM, Pecgen DMX, Guiatuss Clear, Iophen DM NR, Allfen DM, PediaCare Cough & Congestion, Mucinex Children's FreeFrom Cough & Mucus, S-Pack DM, HT Tuss DM, Monafed DM, Hydro-Tuss DM, Alka-Seltzer Plus Maximum Strength Cough & Chest Congestion PowerFast Fizz, Drituss DM, Guaifen DM, Broncotron, Maxi-Tuss DM, Rompe Pecho DM, Su-Tuss DM, Biospec DMX, Muco-Fen 800 DM, Delsym Children’s Cough+ Chest Congestion DM, Guai-Dex, Guaifenesin DM SR, Tussi-Bid, Sudal DM, Iophen DM, Mintab DM, Bidex-A, Mindal DM, Robitussin Children' s Cough & Chest Congestion DM, Z-Cof LA, Extuss LA, ExeFen-DM, Siltussin DM DAS Cough Formula, Simuc-DM, Phlemex, DuraDEX, Relacon LAX, Aquatab DM, Z-Cof LAX, Cheracol D Cough, Robafen DM Clear, DuraDEX Forte, Zotex DMX, Tussi-Organidin DM NR, Tussi-Organidin DM-S NR, Robitussin Cough + Chest Congestion Sugar-Free DM, Guaifen DM NR, Guiadrine DX, Balminil DM + Expectorant Sugar Free, Biocotron, Vicks Nature Fusion Cough & Chest Congestion, G Bid DM, Atuss-12 DX, Cheracol-D, G-Tron, Robafen DM Max, Guaibid DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Cofex-DM, Tussin DM Clear, Congesta DM, Mucosa DM, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM, TabTussin DM, Tusnel Diabetic, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, Duratuss DM 12, Brontuss, Tussi-Organidin-DM, Guaifenex DM, Triaminic Cough & Congestion, Dex-Tuss DM, Fenesin DM IR, Mucus Relief Cough, Gani-Tuss-DM NR, Muco-Fen DM, Guiadrine DM, Fenex-DM, Iobid DM, Q-Bid DM, Touro DM, Respa-DM, Diabetic Tussin Cough and Chest Congestion DM, Mucobid DM, Fenesin DM, Humibid DM Pediatric, Iofen-DM NF, Ambi 1000/55, Phanatuss, Giltuss Honey Cough & Chest Congestion, Naldecon Senior DX, Giltuss HBP Cough & Chest Congestion, Guiatussin-DM, Giltuss Diabetic Cough & Cold, Halotussin DM, Giltuss Children's Honey Cough & Chest Congestion, Double-Tussin DM, Giltuss Children's Cough & Chest Congestion, Halotussin DM Sugar Free, Rhinosyn-DMX, Tuss-DM, Kolephrin GG/DM, Amibid DM, Duraganidin, Genatuss DM, Glycotuss-DM, Mytussin DM, Tolu-Sed DM, Guiacough DM, Lotussin DM, Anti-Tuss DM, Aquabid DM, GG/DM, Mucinex Children's FreeFrom Multi-Symptom Cold & Stuffy Nose, Broncotron Ped, Rompe Pecho CF, Tusso-DMR, Pres Gen Pediatric, Duraphen DM, Sinutuss DM, Nortuss-DE, G-Tusicof, Zotex Pediatric, Tussidex, Zotex, Relhist DMX, Broncotron-D, Supress-DX, G-Supress DX, Tussi-Pres, G-Tron Ped, Tussi-Pres Pediatric, Giltuss Pediatrics, Pres Gen, Tussex, Tussafed-EX, GDP-EX, TriTuss, TriTuss-ER, Tussafed-EX Drops, Certuss-D (old formulation), Dynatuss EX, Dacex-PE, Anextuss, Zotex LAX, Dacex-DM, Duraphen II DM, Duraphen Forte, Maxiphen DM, G-Phen DM, Phlemex-PE, Guaphen II DM, Endacon, Z-Dex, Robafen CF, Tusso-XR, Execof ER, Tusso-DM, Ambi 40/1000/60, Maxiphen-G DM, Z-tuss DM, Deconex DM, PDM GG, ExeTuss-DM, VanaTab DM, Despec NR Drops, Endacon DM, Q-Tussin CF, Desgen, Tusslin, Robitussin Multi-Symptom Cold CF Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough, Mucinex Children's Day Time Multi-Symptom Cold, Giltuss Children's Cough & Cold, Duravent DM, Nivanex DMX, Naldecon-DX Adult, Guiatuss CF, Guiatussin-CF, Naldelate DX Childrens, Naldecon-DX Pediatric, Naldelate DX Pediatric, Nalphen DX Childrens, Nalphen DX Pediatric, Ipsatol Cough Formula, Naldecon-DX Childrens, Uni Tussin CF, Pediacon DX, Phenadex, Tri-Dec, Humibid DM, Z-Cof 8DM, Entex Pac, Entre-Cough, Poly-Vent DM, Medent-DMI, Mardrops-DX, Maxifed DM, PanMist DM, Sudafed Cough, Sudafed Cough Syrup, Balminil DM + Decongestant + Expectorant, TL-Dex DM, Ambi 600/1000/30, Benylin DM-D-E, Ambi 80/780/40, Calmylin 4, Ambi 60/580/30, Ambifed DM, Tenar DM, Novahistine DM Expectorant with Decongestant, Z-COF 12, Donatussin DM Syrup, Anatuss DM, Ambenyl-D, Dimacol, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Suda-Tussin DM, Pseudogest-DM, Tusnel Ped-C, Tusnel-DM Pediatric Drops, Medent DM, Daytime Liquicap, Multi Symptom Cough and Cold, Protuss DM, Med-RX DM, Tussafed-LA, Touro CC, Profen Forte DM, Profen II DM, ExeFen-DMX, Profen II DM Liquid, ExeClear-DM, S-Pak DM, Ru-Tuss DM, Aldex GS DM, Relacon-DM, Coldmist DM, Altarussin CF, Z-Cof DM(obs), Ambifed-G DM, Tusnel Pediatric, Touro CC-LD, Relacon-DM NR, Despec Drops, Pseudo Cough, Relasin DM, Z-Cof DM, Ambi 40 /400 /20, Liquicough DM, Maxifed DMX, Z-Cof 12DM, Trikof-D, Pseudo DM GG, Pseudo Max DMX, SudaTex-DM, Desgen DM (with pseudoephedrine), P-Tuss DM, Delsym Cough+ Soothing Action, Robitussin Medi-Soothers Cough DM, Hot Lemon Cough and Colds Relief DM, PediaCare Daytime Multi-Symptom Cold, Sudafed PE Children's Cold & Cough, Albatussin Pediatric, Albatussin Pediatric Drops, Little Colds Decongestant/Cough, Children's Triacting Daytime, Safetussin CD, Triaminic Thin Strips Day Time Cold & Cough, Triaminic Day Time Cold & Cough, PediaCare Children's 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Dextromethorphan Levels and Effects while Breastfeeding

Summary of Use during Lactation

The amounts of dextromethorphan and its active metabolite in breastmilk are very low and are not expected to affect the nursing infant. It is best to avoid the use of products with a high alcohol content while nursing.

Drug Levels

Dextromethorphan is metabolized to its active metabolite of dextrorphan by CYP2D6. Dextrorphan is further metabolized to dextrorphan glucuronide by UGT2B.

Maternal Levels. Twenty nursing mothers who were extensive metabolizers of CYP2D6 donated a blood sample and completely emptied one breast 2 hours after a single oral dose of dextromethorphan 30 mg. All mothers were at least 3 months postpartum and subjects who were poor, intermediate, or ultra-rapid metabolizers were excluded from the study. The average milk concentration of dextromethorphan at the presumed peak of 2 hours after the dose was 2.5 mcg/L (95% CI 1.5 to 3.9 mcg/L). The average milk concentration of the active metabolite dextrorphan at that time was 14 mcg/L (95% CI 10.7 to 17.9 mcg/L). These values translated to average “worst-case” daily infant dosages of 0.33 mcg/kg and 1.8 mcg/kg, and relative infant dosages of 0.07% and 0.41% for dextromethorphan and dextrorphan, respectively. The authors used published values of serum concentrations after a typical 60 mg twice daily dosage regimen to estimate average steady-state relative infant dosages of 0.04% and 0.07% for dextromethorphan and dextrorphan, respectively.[1] The potential contribution of dextrorphan glucuronide to infant dosage in neonates, who can deconjugate glucuronides some compounds, was not estimated.

Eight women who were given dextromethorphan (dose not specified) following a full-term cesarean section delivery provided milk samples at 4 to 6 hours after their third dose. The authors calculated median estimated relative infant doses to be 0.239% for dextromethorphan and 0.288% for its major active metabolite, dextrorphan.[2]

Infant Levels. Blood samples were obtained at an unspecified time from 8 breastfed infants whose mothers were given dextromethorphan (dose not specified) following a full-term cesarean section delivery. Only one of the 8 infants had a detectable plasma concentration of dextromethorphan. This infant’s mother had a much higher milk level of dextromethorphan than the other 7 women.[2]

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Shum S, Yadav A, Fay E, et al. Infant dextromethorphan and dextrorphan exposure via breast milk from mothers who are CYP2D6 extensive metabolizers. J Clin Pharmacol 2022;62:747-55. [PMC free article: PMC9153952] [PubMed: 34889461]
2.
Lieberman D, O'Brien D, Meyers R, et al. Assessment of dextromethorphan concentration in human breast milk. Am J Obstet Gynecol 2023;228:S119. doi:10.1016/j.ajog.2022.11.242 [CrossRef]

Substance Identification

Substance Name

Dextromethorphan

CAS Registry Number

125-71-3

Drug Class

Breast Feeding

Lactation

Milk, Human

Antitussive Agents

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Further information

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