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Dextromethorphan Pregnancy and Breastfeeding Warnings

Dextromethorphan is also known as: Babee Cof, Benylin DM, Bisolvon Dry, Buckley's Mixture Cough Suppressant, Buckleys Mixture, Cough Syrup DM, Covonia Bronchial Balsam, Creomulsion, Delsym, Delsym 12 Hour Cough Relief, Delsym 12 Hour Cough Relief for Children & Adults, Delsym Children's 12-Hour Cough Relief, DexAlone, Dextromethorphan HBr Adult Formula, Dristan DM, Dry Cough, Duract Max Strength Cough, Pertussin DM, Robitussin Children's Cough Long-Acting, Strepsils Cough, Sucrets Cough, Triaminic Long Acting Cough, Tussinol for Dry Coughs, Vicks Dayquil Cough, Vicks Formula 44

Dextromethorphan Pregnancy Warnings

Dextromethorphan has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of teratogenicity. There are no controlled data in human pregnancy. Dextromethorphan is only recommended for use during pregnancy when benefit outweighs risk.

See references

Dextromethorphan Breastfeeding Warnings

There are no data on the excretion of dextromethorphan into human milk.

Based on the low molecular weight of dextromethorphan some passage into breast milk probably occurs. However, maternal use of dextromethorphan products that do not contain alcohol are probably safe to use during breast-feeding.

See references

References for pregnancy information

  1. Debus O, Kurlemann G, Gehrmann J, Krasemann T "Dextromethorphan in pregnancy." Chest 120 (2001): 1038-40
  2. Andaloro VJ, Monaghan DT, Rosenquist TH "Dextromethorphan and other N-methyl-D-aspartate receptor antagonists are teratogenic in the avian embryo model." Pediatr Res 43 (1998): 1-7
  3. Einarson A, Lyszkiewicz D, Koren G "The safety of dextromethorphan in pregnancy - Results of a controlled study." Chest 119 (2001): 466-9
  4. "Product Information. Benylin DM (dextromethorphan)." Warner Lambert Laboratories, Morris Plains, NJ.
  5. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  2. "Product Information. Benylin DM (dextromethorphan)." Warner Lambert Laboratories, Morris Plains, NJ.

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