Pseudoephedrine use while Breastfeeding

Drugs containing Pseudoephedrine: Bromfed DM, NyQuil, Sudafed Nasal Decongestant, Claritin-D, Actifed, Allegra-D 24 Hour, Robitussin Cold Cough and Flu, Resperal-DM, Mucinex D, Zyrtec-D, Show all 1025 »Sudafed 12-Hour, SudoGest, Claritin-D 24 Hour, Advil Cold and Sinus, Allegra-D 12 Hour, Zutripro, Nyquil Cold Medicine, Semprex-D, Vicks Dayquil Daytime Cold/Flu, Conex, Zyrtec-D 12 Hour, Sudafed 24-Hour, Entex, Dimetapp Elixir, Cheratussin DAC, Aprodine, Tylenol Cold, Alka-Seltzer Cold and Sinus, Anaplex, Zephrex, Drixoral, Vanacof, Nucodine, Theraflu Flu, Cold and Cough Powder, AllerClear D-24 Hour, Advil Allergy Sinus, M-End DM, Loratadine-D 24 Hour, Alavert D-12 Hour Allergy and Sinus, Duralex, Aleve-D Sinus & Cold, Chlor-Trimeton Allergy Decongestant, Suphedrine, Disophrol, Rescon, Lodrane D, Rymed, Sinarest, Stahist AD, Comtrex Allergy Sinus, DuraHist D, Hytussin, Vanacof DX, Hydro-Tussin EXP, Benadryl Children's Allergy And Sinus, Sinus Relief, M-End WC, Coldamine, Dristan Sinus, Dimacol, Despec DM, Ambenyl-D, PanMist DM, Mar-cof BP, Decongestant Cold Formula, Xiral SR, Bidhist-D, Entex PSE, Wal-Zyr D, Duraflu, Histafed, Pannaz, Time-Hist QD, Unifed, Orlenta, Maldec-DM, GP 500, Brotapp, Tusnel, Stahist, Lortuss DM, Allergy & Congestion Relief, SuTan, Dimetane DX, Simplet, Vicks 44D, Profen Forte, Atrogen, M-END, Allerest Maximum Strength, Ambifed CD, Deka, Brometane DX, Tekral, Pseudovent 400, Bromadine-DM, Despec-Tab, Maxifed DM, Tusnel Pediatric, Benadryl Allergy Sinus, Brotapp-DM, LoHist-D, Zotex-D, Maxifed DMX, Histex, LoHist-12D, Sildec, AlleRx Dose Pack, Dicel, De-Congestine, Atrohist Pediatric Capsule, Lodrane 24D, Mintex, Advil Cold and Sinus Liqui-Gels, Allent, Tri-Vent HC, Pancof, Nacon, Clorfed, Lodrane, Coldcough Syrup, Actifed Allergy Day/Night, Welltuss HC, Novafed A, Deconamine, Bromplex HD, J-Cof DHC, Isophen-DF, Tussafed, Nalex Expectorant, Pancof HC, Capmist DM, Poly-Vent DM, Donatussin DM Syrup, Bromaline, Histussin D, Rondamine, Dynatuss, Maldec, Allegra-D 12 Hour Allergy & Congestion, Lodrane 12D, Trikof-D, Trinalin Repetabs, Dexophed, Disobrom, 12 Hour Cold, Dixaphedrine, Tylenol Severe Cold & Flu Night Time, Triafed, Genac, Allerfrim, All Day Allergy-D, Zephrex LA, Guaifenex PSE 60, Desal II, Sinufed, Stamoist E, Respaire-60 SR, Tanafed DMX, Bromdex D, Nalex, Actedril, Atridine, Codimal, Kolephrin, Sinutab Ex-Strength, Tricom, Atuss DS, Genacol Maximum Strength, Triaminic-D Multi-Symptom Cold, NasOpen, Sinutab Maximum Strength Caplets, Vanatab DX, Ritifed, Triacin, Triptifed, M-End DMX, Allergy Relief D, Pseudodine C, Cetiri D, Clarinex-D 12 Hour, Mytussin DAC, Deltuss DMX, Claritin-D 12 Hour, Pseudo GG, Sinutab Maximum Strength Non Drowsy, Afrinol, Efidac, Nomuc-PE, Ru-Tuss Jr., Deltuss DP, Benadryl Cold, CPM-PSE DM Drops, Ru-Tuss, Contac Cold, Allerest No Drowsiness, Sinutab Non Drying, Pseudovent, Nexafed, Robitussin Allergy & Cough, Suphedrin, Silfedrine, Balminil DM + Decongestant, Drixoral Cough & Congestion Liquid Caps, Vanacon, Pedia Relief Infant, Tussgen Expectorant, SRC Expectorant, Deconamine CX, Medtuss HD, Poly-Tussin XP, Sudafed Cough Syrup, Aldex GS DM, Ambi 40 /400 /20, Entex Pac, P-Tuss DM, TL-Dex DM, KG-Tuss HD, Sudafed Cough, Entre-Cough, Spantuss HD, Hydrotussin HD, Tavist NightTime Allergy, Respa SA, Lortuss LQ, Viravan-PDM, Benylin Multi-Symptom, Benaphen Plus, Uni-Cof Expectorant, DiHydro-GP, Welltuss EXP, Pancof EXP, Buckley's DM Decongestant, Dexatrex D, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Entuss-D JR, Entuss-D, Benylin DM-D, Tussin Pediatric Cold and Cough, Allegra-D 24 Hour Allergy & Congestion, Detussin Expectorant, Tussin Cough and Cold, Dur-Tann Forte, Bromatan Plus, TanDur DM, SuTan-DM, Tannate PD-DM, DuraTan Forte, C-Phed DPD Tann, Drixoral Cold and Allergy, Pharmadrine, TanaCof DM, Tannate DMP-DEX, Abatuss DMX, Polaramine Expectorant, Tenar DM, Nalfrx, Z-Cof 8DM, Mardrops-DX, Novahistine DM Expectorant with Decongestant, AllerDur, Tanafed DP, D-Hist D, Histatab D, Hexafed, Duotan PD, Drixomed, Dexaphen SA, Nucofed, Tricode GF, KG-Fed, Cycofed, Notuss-DC, Z-Tuss E, Lortuss EX, Ambifed-G CDX, Suttar SF, Suttar-2, Tusnel C, EndaCof-DC, Codar D, Clarinex-D 24 Hour, Drexophed SR, Desihist SA, Duomine, Polyhist NC, Trifed C, Neo AC, Triacin C, Allerfrin with Codeine, Triafed & Codeine, Benylin DM-D-E, Balminil DM + Decongestant + Expectorant, Z-Cof DM, Relasin DM, Liquicough DM, Z-Cof 12DM, Pseudo DM GG, Pseudo Cough, Despec Drops, Z-Cof DM(obs), Ambifed-G DM, Touro CC-LD, Relacon-DM NR, Pseudo Max DMX, SudaTex-DM, Z-COF 12, Medent-DMI, Calmylin 4, Ambi 600/1000/30, Ambi 80/780/40, ExeFen-DMX, Tusnel-DM Pediatric Drops, Ambi 60/580/30, Ambifed DM, ExeClear-DM, Tusnel Ped-C, Altarussin CF, Coldmist DM, Suda-Tussin DM, Guaifenex DM RX, Pseudogest-DM, Daytime Liquicap, Multi Symptom Cough and Cold, Syn-Rx DM, Dorcol Childrens Cough, Anatuss DM, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Su-Tuss HD Elixir, Protuss DM, Profen II DM Liquid, S-Pak DM, Ru-Tuss DM, Relacon-DM, Profen II DM, Profen Forte DM, Med-RX DM, Tussafed-LA, Touro CC, Robitussin Cough & Cold D, Medent DM, Nasatab LA, Sine-Aid IB, Motrin IB Sinus, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Zymine HC, Rezira, H-C Tussive D, Entuss-D Liquid, SymTan, Liquituss HD, ColdCough HCM, Advil Children's Cold, Allergy Relief D 24 Hour, AlleRx Dose Pack (AM Dose), Sudatrate, Sudafed 12 Hour Pressure+Pain, Sinus & Cold D, Aleve-D Sinus & Headache, Respivent-D, Allerx-D, Leader Allergy Relief D-24, Clear-Atadine-D, Allergy Relief D12, Amdry-D, Extendryl PSE, Histinex D, Iotussin D Liquid, Poly-Vent IR, Medent-LDI, ExeFen-IR, Aldex GS, Mucus Relief D, SudaTex-G, Ambifed, Maxifed, Maxifed-G, Pseudo GG TR, ExeFen, Respaire-30, Entex T, Duratuss GP (old formulation), Detussin, Procof D, Tussafin, Tussgen, P-V-Tussin, Protuss-D, Aquatab D Dose Pack, Tusnel Pediatric Drops, Ambi 60/1000, Ambi 60/580, Ambi 80/780, Quadra-Hist D Pediatric, Quadra-Hist D, Ridifed, LA Nasal Decongestant, Tri-Sudo, Triphed, Vi-Sudo, Hista-Tabs, Atrofed, Allerphed, Triposed, Triofed, Aphedrid, A-Phedrin, Actagen, Allerfrin, Tripohist D, Pediatex TD, Hist-PSE, Trip-PSE, Ed A-Hist PSE, Zymine DXR, Pseudocot-T, Altafed, Biofed-PE, Actacin, Trisofed, Allercon, Zymine-D, Superfed, Sudrine, Chlor-Trimeton Nasal Decongestant, Sudafed Children's Nasal Decongestant, Decofed Liquid, Seudotabs, Ridafed, ElixSure Congestion, Drixoral Non-Drowsy, Children's Dimetapp Decongestant Infant, Cenafed, Genaphed, Decofed, Kid Kare Drops, Novafed, nasofed, Sudafed Congestion, Viravan-P, Seldane-D, Allermed, SudoGest 12 Hour, Myfedrine, Sudodrin, Elixsure Decongestant, Drixoral Decongestant Non-Drowsy, Poly-Vent, Jr., Poly-Vent, Guiadrine II, Demibid II, Iosal II, Guiatex II, Guiadrine II SR, D-Feda II, Deconsal LA, Eudal SR, Ambifed CDX, Sudal 60/500, Tuss-LA, V-Dec-M, Defen-LA, Decongest II, Guiatex PSE, Hi Tex PSE, Guai Sudo, Guaipax PSE, Iotex PSE, Guaifenex PSE 120, Guai-Vent/PSE, Deco-D, Guaifed-PSE, Abletex-PSE, Guiadrine PSE 120, Pseudocot-G, Guaibid D Pediatric, Congestac, Mardrops-EX, Tenar PSE, Guaimax-D, Anatuss LA, Nalex CR, Pseudatex HC, Drituss HD, Hytussin Expectorant, Hydro-Tuss XP, Dynex HD, Entex HC, Touro LA, Fenex-PSE, G-Phed- PD, Nalex Jr, Sinufed Timecelles, Versacaps, Guaivent PD, Guaifed, Guaibid D, Syn-Rx, Nasabid, G-Phed, Respaire-120 SR, Ami-Tex PSE, Pseudo-G/PSI, Guiatex II SR, Guiadrine PSE, We Mist LA, Coldmist, Drituss GP, Miraphen PSE, Durasal II, Pseudovent Ped, H 9600 SR, Guaifenex GP, Dynex, Profen II, We Mist II LA, Panmist-S, Pseudatex, Guaifenex PSE 80, Touro LA-LD, Despec-SR, Guaifenex PSE 85, Levall G, Ambifed-G, Coldmist LA, Coldmist Jr, Sudal SR, Pseudo Max, Panmist JR, Panmist LA, Q-Tussin PE, Mytussin PE, Robichem PE, T-Tussin PE, Tusscidin PE, Mastussin PE, Guiatuss PE, Ru-Tuss DE, Zaptec PSE, Guaifenex RX, Guaitab, Biotuss PE, Tussin PE, Venbid TR, Uni Tussin PE, Robitussin Severe Congestion, Humibid GC, Med-RX, Nasabid SR, Sudafed Non Drying Sinus, S-Pack, Degen II, Robafen PE, Guaivent (Ethex), Altarussin PE, Tussafin Liquid, M-End Max D, Bromfenex, Endacof HC, Histex SR, Bromhist Pediatric, Touro A&H, Endafed, J-Tan D HC, Bromcomp HC, Drocon-CS, SymTan A, Anaplex HD, Bromph HD, Visvex, Shellcap, Shellcap PD, Ultrabrom, M-Hist TD, Iofed, Pseubrom, Lodrane Liquid, Bromfenex PD, Pseubrom-PD, Nalfed PD, Lodrane LD, Respahist, Iofed PD, Ultrabrom PD, Brovex HC, Dimetapp DM, Bromph DM, Q-Tapp DM, Uni-Hist PDX Drops, Allanhist PDX Drops, Brom Tann, Histacol BD Drops, Pediahist DM Drops, Bromhist-DM Drops, Bromaline DM, Bromaxefed DM RF Syrup, Carbofed DM Syrup, Uni-Hist DM Pediatric Drops, Bromplex DM, ProHist DM, P-Hist DM Drops, EndaCof PD Drops, Carbodex DM Syrup, Bromphenex DM, Bromtapp-DM, PSE Brom DM, PBM Allergy, BroveX PSE DM, Dallergy DM, Sildec DM, EndaCof-DM, Neo DM Syrup, BroveX PSE DM Tablets, Nalfed, Touro Allergy, Biodec DM, Pediatex 12 DM, Rondamine DM, Cydec-DM Syrup, Cydec-DM Drops, Dura-Ron DM, Cordron-12 DM, Cordron-DM, Pseudacarb, Allres D, Corzall Plus, Andehist DM NR, Carbodex DM Drops, Carbaxef-DM, Carbofed DM Drops, Carboxine 12 DM, Carboxine DM, Carb PSE 12 DM, PSE Allergy DM, Histex HC, PSE Carb DM Drops, PSE Carbinoxamine DM, Pediatex-DM, Decahist-DM, Cordron-DM NR, Pseudo Carb DM, Mintex DM, Allres Pd, Carb Pseudo-Tan, Bromhist-NR, Di-Bromm, Brovex SR, LoHist-PD, BroveX PD, J-TanD PD, Unit-Hist Drops, Unit-Tex 10/120 ER, Bromaxefed RF Syrup, Andehist NR Syrup, Q-Tapp, Bromhist Pediatric Drops, AccuHist Pediatric, BroveX PSB, B-Vex PD, Corzall, Exall-D, Respi-Tann, Re-Tann, Respi-Tann Pd, Dimaphen, Bromfed SR, LoHist PSB, BroveX PSE, Rynex PSE, Brofed, Bromfed PD, Andehist DM NR Syrup, Anaplex DM, All-Nite Cold, NyQuil Multi-Symptom, All-Nite Multi-Symptom Cold/Flu Relief, Multi-Symptom Nighttime, Tusnel-A, NyCair, Contac Day and Night Cold and Flu, Hexaflu, Sinadrin Plus, Complete Sinus Relief, Drixoral Allergy Sinus, Drixoral Cold and Flu, Drixoral Sinus, Maxiflu DM, Balminil Cough and Flu Sugar Free, Non-Drowsy Super Strength Contac Complete, Day Time Multi Symptom, Contact Cold and Sore Throat, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Contac Severe Cold and Flu Non Drowsy, Comtrex Non-Drowsy, Phlemgesic, Tylenol Cold Severe Congestion Daytime, Flutabs, Theraflu Max-D Severe Cold & Flu, Alka-Seltzer Plus Flu/Body, Drixoral Cold/Flu, Maxiflu CDX, Allpanto-S, Theraflu Flu & Cough, Triaminic Flu, Cough & Fever, Alka-Seltzer Plus-D, Comtrex Sinus and Nasal, Co-Apap, Contac Cold and Flu Maximum Strength, Childrens Tylenol Cold Plus Cough, Comtrex Day and Night, Dristan Cold Maximum Strength, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Tablet, Comtrex Cold and Flu Maximum Strength Liquid, Comtrex Nighttime Flu Therapy, Singlet, Cold Medicine Plus, Allergy Sinus Maximum Strength, Actifed Cold & Sinus, Tavist Allergy/Sinus/Headache, Maxiflu CD, Triaminicin, Sinarest Extra Strength, Tylenol Allergy Sinus, Allerest Sinus, Comtrex Allergy Sinus Maximum Strength, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Daytime Cold and Flu Relief, Daytime Non-Drowsy, Sta-D, Respa-AR, Dicel CD, SymPak II, AccuHist DM Pediatric Syrup, Uni-Hist DM Pediatric Syrup, Ursinus, Actifed Cold and Sinus, Benadryl Allergy Sinus Headache, Sudogest Sinus Maximum Strength, Tavist Sinus, Ephed Plus, Bayer Select Sinus Pain Formula, Bromhist-DM, Pediahist DM Syrup, Bromatane DX, Bromanate DX Cough, Myphetane DX Cough, Bromophed-DX, Liquiphed DM, Myphetane DX, BromTann/DM Tann/PSE Tann, BroveX PSB DM, Histacol DM Pediatric Syrup, AccuHist DM Pediatric Drops, PediaHist DM, Anaplex DMX, Ornex Maximum Strength, Suphedrin Sinus, Actifed Sinus Day and Night, Tylenol Allergy Complete NightTime, Tylenol Sinus NightTime, Tylenol Sinus Day/Night Convenience Pack, Tylenol Sinus Severe Congestion Daytime, Sudafed Sinus Nighttime Plus Pain, Contac Day and Night Allergy, Severe Cold Multi-Symptom, Theraflu (pseudoephedrine) Daytime Severe Cold, Daytime Cold, Theraflu Flu Cold & Cough, Benadryl Severe Allergy & Sinus Headache, Sudafed Triple Action, Ornex, Pseudoephedrine Sinus, Phenapap, Sinarest Sinus, Sinutab Maximum Strength, Sinus Maximum Strength, Suphedrin Plus, Genapap Sinus, Contac Sinus, Dristan Cold Non-Drowsy, Sine-Off Maximum Strength, Sinutab Regular Strength, Tylenol Sinus Maximum Strength, Mintex HC, Pannaz S, Curaler, Clorfed II, Chlorafed, Histafed LA, Sudogest Plus, Aller-Chlor Decongestant, Fedahist Gyrocaps, Codimal-LA Half, Pseudochlor, Rescon-Ed, Cophene No 2, Anamine, Klerist-D, Ryna Liquid, Genaphed Plus, Re2+30, Suclor, Sudal-12, Pediox Chewable, C-Phed Tannate, Histade, CP-Tannic, Suphedrine Plus, Hayfebrol Liquid, Chlor-Trimeton Allergy Decongestant SR, Tavist-DA, Dynahist-ER Pediatric, Brexin LA, Chlorafed Timecelles, Fedahist, Histalet, Tanafed, Chlorafed HS Timecelles, Kronofed-A-Jr, Codimal-LA, Durafed, Duotan, Dynahist ER, Qdall, Histade CR, Chlor-Trimeton Decongestant, Deconamine SR, Dura-Tap/PD, Fedahist Timecaps, ND Clear, Kronofed-A, Chlordrine SR, Anamine TD, Time-Hist, Suphenamine-SR, Rinade-BID, Colfed-A, Chlorphedrin SR, D-Amine-SR, Deconomed SR, Pseudocot-C, Sudal-12 Chewable, Sudal-12 Tannate, Deconsal C Expectorant, Nucodine Expectorant, Guaiatussin DAC, Guiatuss DAC, Cycofed Pediatric Expectorant, Guiatussin DAC, KG-Fed Expectorant, Cycofed Expectorant, Nucochem Pediatric Expectorant, Novadyne Expectorant, Nucochem Expectorant, Nuco-Tuss Pediatric Expectorant, Nucodine Pediatric, KG-Fed Pediatric Expectorant, Nucofed Pediatric Expectorant, Codahistine Expectorant, Gua PC, Guaifenesin DAC Liquid, Novagest with Codeine, Codafed, Dihistine, Guaifen DAC, Biotussin DAC, Tussar SF, Phenylhistine Expectorant, Nuco-Tuss Expectorant, Nucochem, Halotussin DAC, Phenhist Expectorant, Biohist LA (old formulation), AccuHist Drops (old formulation), Comtrex Acute Head Cold, Zodryl DEC, Ambifed-G CD, Maxifed CD, Pseudoephedrine Plus, Triaminic Softchews Cold and Allergy, Duratuss DA, SudaHist, Neutrahist Drops, Sudogest Cold & Allergy, SudoGest Sinus & Allergy, Maxifed CDX, Maxifed-G CD, Co-Histine Expectorant, Deproist with Codeine, Decohistine Expectorant, Dihistine Expectorant with Codeine, Dihistine Expectorant, Tussar-2, Nucofed Expectorant, Robitussin-DAC, Maxifed-G CDX, Ryna-CX, Medent C, Novahistine Expectorant, Relcof PSE, DryMax, Statuss Green, Notuss-NXD, Dihistine DH, Phenylhistine DH, Codehist DH, Decohistine DH, Clofera, Certuss-D, Carbodec, Pediatex 12D, Up and Up All Day Allergy Relief D, Biclora-D, Chlo Tuss (Reformulated), Phenylhistine DH Expectorant, Novadyne DH, Rhinosyn-DM, T-Tanna DM, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Creomulsion Pediatric, Duotan DM, Allres DS, Ryna-C, Co-Histine DH, Codahistine-DH Elixir, Zodryl DAC, Tricode AR, PSE Allergy, Carboxine-D, Cydec, Carbiset, Palgic-DC, Andec, Cardec-S, Mooredec, Carboxine 12D, Coldec, Mintex PSE, Pseudox M, Palgic DS, Biohist LA, Coldec D, Palgic-D, Andec-TR, Pediatex-D, Cordron-D, Cordron-D NR, Cordron-12 D, Pseudo Carb, Carboxine-PSE, Hydro-Tussin CBX, Dura-Ron, Carbic-D, Ex-Dec-TR, Coldec-TR, Andehist, Kidcare Cough and Cold, Children's Nyquil, Atuss HD, Cordron-HC NR, Atuss HS, Notuss-Forte, DuraHist, Advil Children's Allergy Sinus, Cordron-HC, Hydrocof-HC, KG-Tussin, A-G Tussin, P-V-Tussin Syrup, Hydrotuss HC, Hydron PCS, Dallergy PSE, Mescolor, VisRx Dose Pack, Allergy AM-PM Dose Pack, Histatab, RelCof DN PSE, ScopoHist, Pseudo CM TR, Allergy DN, PCM-LA, Hista-Vent PSE, Amdry-C, AllePak, Rhinaclear, Q-V Tussin, Tussin-V, Entre-S, AccuHist PDX Drops, Esocor P, Mesehist DM, Kidkare Cough/Cold, Neutrahist PDX Drops, Maxichlor PSE DM, Tanafed-DM, Rescon-DM, C-Phed DM, Atuss-12 DM, Dicel DM, Tricof, Hydro-Tussin DHC, JayCof-HC, Tussend, Notuss, Hexatussin, Hyphed, Pediatex HC, Histinex PV, Uni-Cof, Dihydro-CP, Z-Tuss 2, Lemohist Plus, Detuss, Codafed Pediatric

Pseudoephedrine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Although the small amounts of pseudoephedrine in breastmilk are unlikely to harm the nursing infant, it may cause occasional irritability. A single dose of pseudoephedrine decreases milk production acutely and repeated use seems to interfere with lactation. Mothers with newborns whose lactation is not yet well established or mothers who are having difficulties producing sufficient milk should not receive pseudoephedrine.

Drug Levels

Maternal Levels. A single oral dose of 60 mg of pseudoephedrine in 3 women resulted in peak milk levels of less than 1 mg/L 1 hour after the dose.[1] Other authors used data from this study to calculate the amount excreted in milk to be 5.5% of the weight-adjusted maternal dosage.[2] After a 60 mg oral dose of immediate-release pseudoephedrine, peak milk levels averaging 698 mcg/L occurred 1.7 hours after the dose, and half-life in milk was 5.5 hours. A fully breastfed infant would receive a dose of 4.3% (range 2.2 to 6.7%) of the maternal weight-adjusted dose.[2]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Irritability was reported in 20% of infants exposed to pseudoephedrine in one study of breastfeeding mothers.[3]

Possible Effects on Lactation

After a single dose of pseudoephedrine 60 mg orally in 8 nursing mothers, there was a mean 24% decrease in milk production. No change in blood flow to the breast was detected that could explain the decreased milk production; there was a 13.5% decrease in serum prolactin after pseudoephedrine, but this change did not achieve statistical significance. Oxytocin levels were not measured.[2]

Alternate Drugs to Consider

Oxymetazoline

References

1. Findlay JW, Butz RF et al. Pseudoephedrine and triprolidine in plasma and breast milk of nursing mothers. Br J Clin Pharmacol. 1984;18:901-6. PMID: 6529531

2. Aljazaf K, Hale TW et al. Pseudoephedrine: effects on milk production in women and estimation of infant exposure via breastmilk. Br J Clin Pharmacol. 2003;56:18-24. PMID: 12848771

3. Ito S, Blajchman A et al. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993;168:1393-9. PMID: 8498418

Pseudoephedrine Identification

Substance Name

Pseudoephedrine

CAS Registry Number

90-82-4

Drug Class

  • Adrenergic Agents
  • Adrenergic Alpha-Agonists
  • Central Nervous System Stimulants
  • Sympathomimetics
  • Vasoconstrictor Agents

Administrative Information

LactMed Record Number

231

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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