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Pseudoephedrine use while Breastfeeding

Drugs containing Pseudoephedrine: Bromfed DM, NyQuil, Sudafed Nasal Decongestant, Claritin-D, Mucinex D, Robitussin Cold Cough and Flu, Resperal-DM, Allegra-D 24 Hour, Actifed, Zyrtec-D, Show all 1022 »Sudafed 12-Hour, Vicks Dayquil Daytime Cold/Flu, SudoGest, Allegra-D 12 Hour, Claritin-D 24 Hour, Zutripro, Nyquil Cold Medicine, Cheratussin DAC, Entex, Sudafed 24-Hour, Tylenol Cold, Semprex-D, Aprodine, Zyrtec-D 12 Hour, Anaplex, Dimetapp Elixir, Sinarest, Advil Cold and Sinus, Conex, Loratadine-D 24 Hour, Drixoral, Suphedrine, Rymed, Vanacof, Tusnel, Aleve-D Sinus & Cold, Zephrex, Alka-Seltzer Cold and Sinus, Theraflu Flu, Cold and Cough Powder, Stahist AD, M-End DM, Despec DM, Vanacof DX, AllerClear D-24 Hour, Benadryl Allergy Sinus, Disophrol, Dristan Sinus, Duraflu, Alavert D-12 Hour Allergy and Sinus, Wal-Zyr D, Pseudovent 400, Hydro-Tussin EXP, Chlor-Trimeton Allergy Decongestant, Mar-cof BP, Hytussin, Phenylhistine Expectorant, Bidhist-D, Lodrane 12D, Lodrane D, Sinutab Ex-Strength, Rescon, Stahist, Ambenyl-D, Decongestant Cold Formula, Coldamine, Bromaxefed DM RF Syrup, Dexaphen SA, Dimetane DX, Comtrex Allergy Sinus, Afrinol, Deka, Nucodine, Dicel DM, M-End DMX, Unifed, Maxifed DM, GP 500, Tusnel Pediatric, Allergy & Congestion Relief, Ru-Tuss, Claritin-D 12 Hour, Poly-Vent DM, Pannaz, Coldcough Syrup, Lortuss DM, Entex PSE, Congestac, Benadryl Children's Allergy And Sinus, Novafed A, Despec-Tab, Vicks 44D, Orlenta, Histafed, Allerest Maximum Strength, Bromaline, Duralex, Sildec, Atrogen, Z-COF 12, Donatussin DM Syrup, Maldec-DM, Histussin D, Trikof-D, Pancof HC, Rezira, Nalex Expectorant, Dynatuss, Respi-Tann, Xiral SR, All-Nite Cold, Advil Allergy Sinus, PanMist DM, Dimacol, Tussafed, Protuss DM, Zotex-D, Maxifed DMX, Deconamine, LoHist-D, Lodrane, J-Cof DHC, Tekral, Pancof, M-END, Advil Cold and Sinus Liqui-Gels, Tussend, Allent, Lodrane 24D, LoHist-12D, Dicel, Histex, Coldec, Rondamine, Maldec, Deconamine SR, Esocor P, Nacon, Tri-Vent HC, CPM-PSE DM Drops, Curaler, Clorfed, Genacol Maximum Strength, NasOpen, Stamoist E, Respaire-60 SR, Sinutab Maximum Strength, Children's Dimetapp Decongestant Infant, Brotapp-DM, Contac Cold, Efidac, Triacin, Sinutab Maximum Strength Non Drowsy, Nalex, Poly-Vent IR, Ru-Tuss Jr., Maxifed, All Day Allergy-D, Allergy Relief D, Silfedrine, Nexafed, Sinufed, Desal II, Humibid GC, Ritifed, Mytussin DAC, Maxifed CD, Decongest II, Guaifenex PSE 60, Guaifenex PSE 80, Nomuc-PE, Pseudo GG, Benadryl Cold, Pseudovent, Profen Forte, Robitussin Severe Congestion, Entex T, Codimal, Simplet, M-End WC, Kolephrin, Trinalin Repetabs, Genac, Contac Day and Night Cold and Flu, Q-Tapp DM, Tylenol Severe Cold & Flu Night Time, Bromadine-DM, Brometane DX, Bromophed-DX, Allerfrin, Triafed, Dixaphedrine, Triposed, DuraHist D, Disobrom, 12 Hour Cold, Deltuss DP, SuTan, Ambi 40 /400 /20, Pedia Relief Infant, P-Tuss DM, Balminil DM + Decongestant, Aldex GS DM, Entre-Cough, Drixoral Cough & Congestion Liquid Caps, Sudafed Cough, Entex Pac, TL-Dex DM, KG-Tuss HD, Sudafed Cough Syrup, Viravan-PDM, Tussadur-HD, Vanex Expectorant, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, Allegra-D 12 Hour Allergy & Congestion, Medent DM, Deconamine CX, Poly-Tussin XP, Entuss-D, Decotuss-HD, Entuss-D JR, Allegra-D 24 Hour Allergy & Congestion, SRC Expectorant, Lortuss LQ, Welltuss EXP, Hydrotussin HD, Pancof EXP, Buckley's DM Decongestant, Benylin DM-D, Dexatrex D, DiHydro-GP, Uni-Cof Expectorant, Tavist NightTime Allergy, Respa SA, Actifed Allergy Day/Night, Benylin Multi-Symptom, Benaphen Plus, Tussin Pediatric Cold and Cough, Pseudogest-DM, C-Phed DPD Tann, Tannate DMP-DEX, DuraTan Forte, Bromatan Plus, Dur-Tann Forte, Tanafed DMX, TanaCof DM, Dexophed, Duomine, Drixomed, Drixoral Cold and Allergy, Pharmadrine, TanDur DM, SuTan-DM, Duotan PD, Hexafed, Tanafed DP, AllerDur, Nalfrx, Histatab D, D-Hist D, Tannate PD-DM, Deltuss DMX, Abatuss DMX, Polaramine Expectorant, Desihist SA, Drexophed SR, Z-Tuss E, Lortuss EX, Tricode GF, Nucofed, KG-Fed, Tusnel C, Suttar-2, Ambifed CD, Ambifed CDX, Ambifed-G CDX, Suttar SF, Cycofed, Notuss-DC, Pseudodine C, Trifed C, Polyhist NC, Clarinex-D 24 Hour, Clarinex-D 12 Hour, Triafed & Codeine, Allerfrin with Codeine, EndaCof-DC, Codar D, Neo AC, Triacin C, Tenar DM, Z-Cof 8DM, Relasin DM, Pseudo Cough, Z-Cof DM, Liquicough DM, Z-Cof 12DM, Despec Drops, Relacon-DM NR, Altarussin CF, Coldmist DM, Z-Cof DM(obs), Ambifed-G DM, Touro CC-LD, Pseudo DM GG, Pseudo Max DMX, Medent-DMI, ExeFen-DMX, Calmylin 4, Capmist DM, Ambi 600/1000/30, Tusnel-DM Pediatric Drops, Tusnel Ped-C, SudaTex-DM, Ambi 60/580/30, Ambifed DM, ExeClear-DM, Relacon-DM, Ru-Tuss DM, Rhinosyn-X, Ru-Tuss Expectorant, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Novahistine DMX, Anatuss DM, Mardrops-DX, Novahistine DM Expectorant with Decongestant, Benylin DM-D-E, Balminil DM + Decongestant + Expectorant, Suda-Tussin DM, Medtuss HD, Profen Forte DM, Robitussin Cough & Cold D, Profen II DM, Profen II DM Liquid, S-Pak DM, Touro CC, Tussafed-LA, Daytime Liquicap, Multi Symptom Cough and Cold, Tussin Cough and Cold, Med-RX DM, Ambi 80/780/40, G-Phed- PD, Motrin Sinus Headache, Motrin Childrens Cold, Advil Children's Cold, Allergy Relief D 24 Hour, Clear-Atadine-D, Motrin Cold and Flu, Sine-Aid IB, Liquituss HD, SymTan, ColdCough HCM, Zymine HC, Motrin IB Sinus, Leader Allergy Relief D-24, Allergy Relief D12, Sinus & Cold D, Sudafed 12 Hour Pressure+Pain, Quadra-Hist D Pediatric, Quadra-Hist D, Drixoral Non-Drowsy, AlleRx Dose Pack (AM Dose), Sudatrate, Amdry-D, Extendryl PSE, Allerx-D, Respivent-D, H-C Tussive D, Entuss-D Liquid, ExeFen-IR, Medent-LDI, Aldex GS, Mucus Relief D, Duratuss GP (old formulation), SudaTex-G, Ambifed, Maxifed-G, Poly-Vent, Jr., Pseudo GG TR, ExeFen, Respaire-30, Tusnel Pediatric Drops, Ambi 60/1000, Tussgen, Tussafin, P-V-Tussin, Iotussin D Liquid, Histinex D, Detussin, Procof D, Ambi 60/580, Ambi 80/780, Aquatab D Dose Pack, Protuss-D, ElixSure Congestion, Cenafed, Ridifed, LA Nasal Decongestant, Tri-Sudo, Triphed, Vi-Sudo, Hista-Tabs, Atrofed, Aphedrid, Triofed, A-Phedrin, Actedril, Atridine, Triptifed, Actagen, Tripohist D, Pediatex TD, Hist-PSE, Trip-PSE, Ed A-Hist PSE, Zymine DXR, Pseudocot-T, Altafed, Biofed-PE, Actacin, Trisofed, Allerphed, Allercon, Decofed Liquid, Sudafed Children's Nasal Decongestant, Decofed, Kid Kare Drops, Myfedrine, Chlor-Trimeton Nasal Decongestant, Superfed, Genaphed, Ridafed, Seudotabs, Sudrine, Sudodrin, Elixsure Decongestant, Viravan-P, Sudafed Congestion, Seldane-D, Allerfrim, Zymine-D, Suphedrin, Novafed, Drixoral Decongestant Non-Drowsy, SudoGest 12 Hour, Allermed, nasofed, Poly-Vent, Guaifenex PSE 85, Deconsal LA, V-Dec-M, D-Feda II, Demibid II, Guiadrine II, Tuss-LA, Sudal 60/500, Guaibid D Pediatric, Guaivent PD, Pseudocot-G, Nasatab LA, Eudal SR, Iosal II, Guiatex II, Guaifenex PSE 120, Guai-Vent/PSE, Hi Tex PSE, Guiatex PSE, Guai Sudo, Guiadrine PSE 120, Abletex-PSE, Guiadrine II SR, Defen-LA, Deco-D, Guaifed-PSE, Versacaps, Sinufed Timecelles, Pseudatex HC, Entex HC, Nalex CR, Mardrops-EX, Zephrex LA, Dynex HD, Hydro-Tuss XP, Su-Tuss HD Elixir, Vanacon, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Tenar PSE, Guaimax-D, Guaibid D, Respaire-120 SR, Guaifed, Nalex Jr, Codafed Pediatric, G-Phed, Nasabid, Anatuss LA, Touro LA, Fenex-PSE, Syn-Rx, Guaipax PSE, Iotex PSE, Miraphen PSE, Durasal II, Guiadrine PSE, Guiatex II SR, We Mist LA, Profen II, Dynex, Panmist JR, Panmist LA, H 9600 SR, Pseudovent Ped, Guaifenex GP, Coldmist, Drituss GP, Levall G, Ambifed-G, Pseudatex, Touro LA-LD, Despec-SR, Pseudo Max, Sudal SR, We Mist II LA, Panmist-S, Coldmist LA, Coldmist Jr, Nasabid SR, Med-RX, Guiatuss PE, Biotuss PE, Mastussin PE, Mytussin PE, Q-Tussin PE, Guaitab, Guaifenex RX, Ami-Tex PSE, Pseudo-G/PSI, Zaptec PSE, Ru-Tuss DE, Robichem PE, T-Tussin PE, S-Pack, Altarussin PE, Sudafed Non Drying Sinus, Sinutab Non Drying, Uni Tussin PE, Guaivent (Ethex), Robafen PE, Tusscidin PE, Tussin PE, Venbid TR, Degen II, Spantuss HD, M-End Max D, Histex SR, Bromfenex, Bromhist Pediatric, Endafed, Shellcap, Touro A&H, Endacof HC, J-Tan D HC, Bromplex HD, Anaplex HD, Bromph HD, Visvex, Bromcomp HC, Shellcap PD, Lodrane LD, Iofed, Ultrabrom, Pseubrom, Lodrane Liquid, Nalfed, M-Hist TD, Bromfenex PD, Respahist, Nalfed PD, Iofed PD, Ultrabrom PD, Pseubrom-PD, Drocon-CS, SymTan A, Histacol BD Drops, Allanhist PDX Drops, Brom Tann, ProHist DM, Sildec DM, P-Hist DM Drops, Robitussin Allergy & Cough, Uni-Hist PDX Drops, Bromplex DM, Uni-Hist DM Pediatric Drops, Bromhist-DM Drops, Pediahist DM Drops, Bromph DM, Dallergy DM, EndaCof-DM, Bromtapp-DM, Bromphenex DM, PSE Brom DM, Dimetapp DM, Brovex HC, EndaCof PD Drops, Carbodex DM Syrup, BroveX PSE DM Tablets, Neo DM Syrup, BroveX PSE DM, PBM Allergy, Bromdex D, Touro Allergy, Andehist NR Syrup, Cydec-DM Syrup, Rondamine DM, Dura-Ron DM, Cydec-DM Drops, Carbofed DM Drops, Carbaxef-DM, Biodec DM, Pediatex 12 DM, Andehist DM NR, Corzall Plus, Carbodex DM Drops, Cordron-DM, Cordron-12 DM, Decahist-DM, Pediatex-DM, PSE Allergy DM, Carb PSE 12 DM, Histex HC, Mintex HC, Pannaz S, Carboxine 12 DM, Carboxine DM, Pseudo Carb DM, Cordron-DM NR, Mintex DM, PSE Carbinoxamine DM, PSE Carb DM Drops, Pseudacarb, Allres D, Brovex SR, Bromhist-NR, LoHist-PD, J-TanD PD, BroveX PSB, BroveX PD, Di-Bromm, Unit-Hist Drops, Q-Tapp, Bromaxefed RF Syrup, Bromhist Pediatric Drops, AccuHist Pediatric, Unit-Tex 10/120 ER, B-Vex PD, BroveX PSE, Re-Tann, Corzall, Respi-Tann Pd, Carb Pseudo-Tan, Allres Pd, Exall-D, Bromfed SR, Rynex PSE, LoHist PSB, Brotapp, Brofed, Bromfed PD, Carbofed DM Syrup, Bromaline DM, All-Nite Multi-Symptom Cold/Flu Relief, NyQuil Multi-Symptom, Multi-Symptom Nighttime, NyCair, Maxiflu DM, Tusnel-A, Hexaflu, Drixoral Sinus, Complete Sinus Relief, Drixoral Cold/Flu, Sinadrin Plus, Drixoral Allergy Sinus, Drixoral Cold and Flu, Balminil Cough and Flu Sugar Free, Tylenol Cold Severe Congestion Daytime, Contact Cold and Sore Throat, Non-Drowsy Super Strength Contac Complete, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Daytime Cold and Flu Relief, Day Time Multi Symptom, Contac Severe Cold and Flu Non Drowsy, Flutabs, Phlemgesic, Theraflu Max-D Severe Cold & Flu, Alka-Seltzer Plus Flu/Body, Comtrex Non-Drowsy, Maxiflu CDX, Maxiflu CD, Allpanto-S, Theraflu Flu & Cough, Triaminic Flu, Cough & Fever, Alka-Seltzer Plus-D, Comtrex Nighttime Flu Therapy, Comtrex Sinus and Nasal, Contac Cold and Flu Maximum Strength, Childrens Tylenol Cold Plus Cough, Comtrex Day and Night, Dristan Cold Maximum Strength, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Tablet, Comtrex Cold and Flu Maximum Strength Liquid, Singlet, Tricom, Allergy Sinus Maximum Strength, Sinutab Maximum Strength Caplets, Cold Medicine Plus, Actifed Cold & Sinus, Tavist Allergy/Sinus/Headache, Triaminicin, Sinarest Extra Strength, Tylenol Allergy Sinus, Allerest Sinus, Comtrex Allergy Sinus Maximum Strength, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Daytime Non-Drowsy, Theraflu (pseudoephedrine) Daytime Severe Cold, Dicel CD, Sta-D, SymPak II, Uni-Hist DM Pediatric Syrup, Bromhist-DM, AccuHist DM Pediatric Syrup, Respa-AR, Ursinus, Ephed Plus, Tavist Sinus, Sinus Relief, Bayer Select Sinus Pain Formula, Actifed Cold and Sinus, Pediahist DM Syrup, Histacol DM Pediatric Syrup, Myphetane DX Cough, Bromatane DX, Liquiphed DM, Anaplex DM, Andehist DM NR Syrup, Bromanate DX Cough, Myphetane DX, AccuHist DM Pediatric Drops, BroveX PSB DM, PediaHist DM, Anaplex DMX, BromTann/DM Tann/PSE Tann, Benadryl Allergy Sinus Headache, Sudogest Sinus Maximum Strength, Tylenol Sinus NightTime, Actifed Sinus Day and Night, Tylenol Sinus Day/Night Convenience Pack, Tylenol Sinus Severe Congestion Daytime, Ornex, Sudafed Triple Action, Tylenol Allergy Complete NightTime, Sudafed Sinus Nighttime Plus Pain, Daytime Cold, Severe Cold Multi-Symptom, Theraflu Flu Cold & Cough, Benadryl Severe Allergy & Sinus Headache, Contac Day and Night Allergy, Dristan Cold Non-Drowsy, Contac Sinus, Sinus Maximum Strength, Sinarest Sinus, Suphedrin Sinus, Ornex Maximum Strength, Allerest No Drowsiness, Pseudoephedrine Sinus, Phenapap, Sinutab Regular Strength, Sine-Off Maximum Strength, Tylenol Sinus Maximum Strength, Genapap Sinus, Suphedrin Plus, Pseudox M, Mintex PSE, Clorfed II, Fedahist Gyrocaps, Chlorafed, Histafed LA, Sudogest Plus, Aller-Chlor Decongestant, Codimal-LA Half, Klerist-D, Rescon-Ed, Brexin LA, Pseudochlor, Cophene No 2, Anamine, Ryna Liquid, Genaphed Plus, Mintex, Histade, Suclor, Re2+30, Sudal-12, CP-Tannic, Dynahist-ER Pediatric, Suphedrine Plus, Hayfebrol Liquid, Atrohist Pediatric Capsule, Chlor-Trimeton Allergy Decongestant SR, Tavist-DA, Chlorafed Timecelles, Time-Hist, Fedahist, Histalet, Tanafed, Chlorafed HS Timecelles, Kronofed-A-Jr, Codimal-LA, Durafed, Duotan, Qdall, Relcof PSE, Dynahist ER, Histade CR, Chlor-Trimeton Decongestant, Dura-Tap/PD, Fedahist Timecaps, Kronofed-A, Isophen-DF, ND Clear, Chlordrine SR, Anamine TD, Suphenamine-SR, Rinade-BID, Colfed-A, Chlorphedrin SR, D-Amine-SR, Deconomed SR, Pseudocot-C, Pediox Chewable, C-Phed Tannate, KG-Fed Expectorant, Cycofed Expectorant, Nucodine Expectorant, Deconsal C Expectorant, Guiatuss DAC, Guaiatussin DAC, Nucodine Pediatric, Nuco-Tuss Pediatric Expectorant, Halotussin DAC, Phenhist Expectorant, Novadyne Expectorant, Nucochem Pediatric Expectorant, Nucochem Expectorant, Guiatussin DAC, Cycofed Pediatric Expectorant, Gua PC, Dihistine, Codahistine Expectorant, Guaifenesin DAC Liquid, Novagest with Codeine, Guaifen DAC, Nucochem, Nucofed Pediatric Expectorant, KG-Fed Pediatric Expectorant, Tussar SF, Biotussin DAC, Nuco-Tuss Expectorant, Dihistine Expectorant, Dihistine Expectorant with Codeine, Triaminic Softchews Cold and Allergy, SudoGest Sinus & Allergy, Pseudoephedrine Plus, AccuHist Drops (old formulation), Comtrex Acute Head Cold, Biohist LA (old formulation), Sudogest Cold & Allergy, Neutrahist Drops, Sudal-12 Chewable, De-Congestine, Sudal-12 Tannate, SudaHist, Duratuss DA, Zodryl DEC, Ambifed-G CD, Tussar-2, Nucofed Expectorant, Deproist with Codeine, Co-Histine Expectorant, Decohistine Expectorant, Novahistine Expectorant, Medent C, Maxifed-G CD, Maxifed CDX, Maxifed-G CDX, Robitussin-DAC, Ryna-CX, DryMax, ScopoHist, Dihistine DH, Statuss Green, Phenylhistine DH, Decohistine DH, Phenylhistine DH Expectorant, Codehist DH, Notuss-NXD, Clofera, Biclora-D, Up and Up All Day Allergy Relief D, Chlo Tuss (Reformulated), Vanatab DX, Certuss-D, Novadyne DH, Co-Histine DH, Rhinosyn-DM, T-Tanna DM, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Creomulsion Pediatric, Duotan DM, Allres DS, Codahistine-DH Elixir, Ryna-C, Zodryl DAC, Tricode AR, Triaminic-D Multi-Symptom Cold, Cetiri D, Carbodec, Mooredec, Andec, Cardec-S, Palgic-D, Carbic-D, Andec-TR, Palgic-DC, Cydec, Biohist LA, Palgic DS, Coldec D, Carboxine 12D, Carbiset, Dura-Ron, Ex-Dec-TR, Pseudo Carb, Cordron-12 D, Carboxine-D, PSE Allergy, Pediatex 12D, Cordron-D NR, Pediatex-D, Andehist, Coldec-TR, Hydro-Tussin CBX, Carboxine-PSE, Cordron-D, Kidcare Cough and Cold, Children's Nyquil, Atuss HS, Atuss HD, Notuss-Forte, Advil Children's Allergy Sinus, DuraHist, AlleRx Dose Pack, Cordron-HC NR, Cordron-HC, P-V-Tussin Syrup, KG-Tussin, Hydrotuss HC, Hydron PCS, Hydrocof-HC, Dallergy PSE, Mescolor, Allergy AM-PM Dose Pack, Pseudo CM TR, VisRx Dose Pack, Histatab, RelCof DN PSE, Allergy DN, Rhinaclear, PCM-LA, Hista-Vent PSE, Amdry-C, Time-Hist QD, AllePak, A-G Tussin, Q-V Tussin, Entre-S, AccuHist PDX Drops, Mesehist DM, Kidkare Cough/Cold, Tricof, Neutrahist PDX Drops, Maxichlor PSE DM, Tanafed-DM, Rescon-DM, C-Phed DM, Atuss-12 DM, Atuss DS, Hydro-Tussin DHC, Dihydro-CP, Notuss, JayCof-HC, Hexatussin, Hyphed, Tussin-V, Welltuss HC, Pediatex HC, Z-Tuss 2, Uni-Cof, Lemohist Plus, Detuss, Histinex PV, Codafed

Pseudoephedrine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Although the small amounts of pseudoephedrine in breastmilk are unlikely to harm the nursing infant, it may cause occasional irritability. A single dose of pseudoephedrine decreases milk production acutely and repeated use seems to interfere with lactation. Mothers with newborns whose lactation is not yet well established or mothers who are having difficulties producing sufficient milk should not receive pseudoephedrine.

Drug Levels

Maternal Levels. A single oral dose of 60 mg of pseudoephedrine in 3 women resulted in peak milk levels of less than 1 mg/L 1 hour after the dose.[1] Other authors used data from this study to calculate the amount excreted in milk to be 5.5% of the weight-adjusted maternal dosage.[2] After a 60 mg oral dose of immediate-release pseudoephedrine, peak milk levels averaging 698 mcg/L occurred 1.7 hours after the dose, and half-life in milk was 5.5 hours. A fully breastfed infant would receive a dose of 4.3% (range 2.2 to 6.7%) of the maternal weight-adjusted dose.[2]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Irritability was reported in 20% of infants exposed to pseudoephedrine in one study of breastfeeding mothers.[3]

Possible Effects on Lactation

After a single dose of pseudoephedrine 60 mg orally in 8 nursing mothers, there was a mean 24% decrease in milk production. No change in blood flow to the breast was detected that could explain the decreased milk production; there was a 13.5% decrease in serum prolactin after pseudoephedrine, but this change did not achieve statistical significance. Oxytocin levels were not measured.[2]

Alternate Drugs to Consider

Oxymetazoline

References

1. Findlay JW, Butz RF et al. Pseudoephedrine and triprolidine in plasma and breast milk of nursing mothers. Br J Clin Pharmacol. 1984;18:901-6. PMID: 6529531

2. Aljazaf K, Hale TW et al. Pseudoephedrine: effects on milk production in women and estimation of infant exposure via breastmilk. Br J Clin Pharmacol. 2003;56:18-24. PMID: 12848771

3. Ito S, Blajchman A et al. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993;168:1393-9. PMID: 8498418

Pseudoephedrine Identification

Substance Name

Pseudoephedrine

CAS Registry Number

90-82-4

Drug Class

  • Adrenergic Agents
  • Adrenergic Alpha-Agonists
  • Central Nervous System Stimulants
  • Sympathomimetics
  • Vasoconstrictor Agents

Administrative Information

LactMed Record Number

231

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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