Pantoprazole use while Breastfeeding
Drugs containing Pantoprazole: Protonix, Protonix IV
Pantoprazole Levels and Effects while Breastfeeding
Summary of Use during Lactation
Limited information indicates that maternal pantoprazole doses of 40 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants.
Drug Levels
Maternal Levels. A mother who was 10 months postpartum and partially nursing her infant was given a single 40 mg dose of oral pantoprazole. Pantoprazole was detectable in milk only 2 and 4 hours after the dose with milk levels of 36 mcg/L and 24 mcg/L, respectively, at those times. It was not detectable (<10 mcg/L) in milk at 6, 8 and 24 hours after the dose. The authors estimated that a fully breastfed infant would receive 0.14% of the maternal weight-adjusted dosage.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Cimetidine, Famotidine, Nizatidine, Omeprazole, Ranitidine, Sucralfate
References
1. Plante L, Ferron GM, Unruh M et al. Excretion of pantoprazole in human breast. J Reprod Med. 2004;49:825-7. PMID: 15568407
Pantoprazole Identification
Substance Name
CAS Registry Number
102625-70-7
Drug Class
- Anti-Ulcer Agents
Administrative Information
LactMed Record Number
409
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2012-10-02
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Pantoprazole use during Pregnancy
- Pantoprazole, Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
