Skip to main content

Pantoprazole Dosage

Medically reviewed by Drugs.com. Last updated on Dec 13, 2023.

Applies to the following strengths: 40 mg; 20 mg; 0.4 mg/mL-NaCl 0.9%; 0.8 mg/mL-NaCl 0.9%; 4 mg/mL

Usual Adult Dose for Erosive Esophagitis

Treatment: 40 mg orally once a day


Maintenance: 40 mg orally once daily

Comments:

Uses:

Usual Adult Dose for Gastroesophageal Reflux Disease

Oral: 40 mg orally once a day


Parenteral: 40 mg via IV infusion once a day, given over at least 2 minutes OR over 15 minutes

Comments:

Uses:

Usual Adult Dose for Zollinger-Ellison Syndrome

Oral: 40 mg orally 2 times a day


Parenteral:

Comments:

Uses:

Usual Adult Dose for Pathological Hypersecretory Conditions

Oral: 40 mg orally 2 times a day


Parenteral:

Comments:

Uses:

Usual Pediatric Dose for Erosive Esophagitis

5 years and older:
15 to less than 40 kg: 20 mg orally once a day
40 kg and greater: 40 mg orally once a day
Duration of therapy: Up to 8 weeks

Comment: Safety has not been established in treatment beyond 8 weeks.

Uses:

Usual Pediatric Dose for Gastroesophageal Reflux Disease

5 years and older:
15 to less than 40 kg: 20 mg orally once a day
40 kg and greater: 40 mg orally once a day
Duration of therapy: Up to 8 weeks

Comment: Safety has not been established in treatment beyond 8 weeks.

Uses:

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

IV: Data not available

Oral: Doses over 40 mg/day have not been studied in patients with liver impairment. No adjustment recommended.

Dose Adjustments

CYP450 2C19 Poor Metabolizers:
Adults: No adjustment recommended.
Pediatric patients: Oral dose reductions should be considered.

Pathological Hypersecretion (including Zollinger-Ellison syndrome):

Precautions

CONTRAINDICATIONS:


Safety and efficacy of oral formulations have not been established in patients younger than 5 years. The IV formulation is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements: The manufacturer product information should be consulted.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

IV compatibility: The manufacturer product information should be consulted.

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.