Fenoprofen use while Breastfeeding
Drugs containing Fenoprofen: Nalfon
Fenoprofen Levels and Effects while Breastfeeding
Summary of Use during Lactation
Some reviewers consider fenoprofen to be acceptable during breastfeeding.[1] Because there is little published experience with fenoprofen during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date. Data are limited to those reported in a review article by the drug's manufacturer in which no study details are reported. After a dose of 600 mg every 6 hours for 4 days in postpartum mothers, breastmilk fenoprofen levels were reportedly 1.6% of those in maternal plasma and below those accurately detected by the assay (assay limit not stated).[2] Additionally, fenoprofen has glucuronide metabolites that could be absorbed as fenoprofen by a newborn. Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Acetaminophen, Flurbiprofen, Ibuprofen, Indomethacin, Naproxen, Piroxicam
References
1. Brooks PM, Needs CJ. Antirheumatic drugs in pregnancy and lactation. Baillieres Clin Rheumatol. 1990;4:157-71. PMID: 2282661
2. Rubin A, Chernish SM, Crabtree R et al. A profile of the physiological disposition and gastro-intestinal effects of fenoprofen in man. Curr Med Res Opin. 1974;2:529-44. PMID: 4615886
Fenoprofen Identification
Substance Name
CAS Registry Number
31879-05-7
Drug Class
- Analgesic Agents
- Nonsteroidal Antiinflammatory Agents
Administrative Information
LactMed Record Number
110
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2010-09-02
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Fenoprofen use during Pregnancy
- Fenoprofen Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
