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Fenoprofen Pregnancy and Breastfeeding Warnings

Fenoprofen is also known as: Nalfon

Fenoprofen Pregnancy Warnings

Fenoprofen has been assigned by the FDA to pregnancy category C prior to 30-weeks gestation and category D starting at 30-weeks gestation. Fenoprofen and other NSAIDs should be avoided by pregnant women as premature closure of the ductus arteriosus in the fetus may occur. Fenoprofen can cause fetal harm when administered to a pregnant woman starting at 30-weeks gestation. If used during this time period in pregnancy, the patient should be apprised of the potential hazard to the fetus. There are no adequate and well-controlled data in human pregnancy. Prior to 30-weeks gestation, fenoprofen should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

The effects of fenoprofen on labor and delivery in pregnant women are unknown. In rat studies, maternal exposure to NSAIDs, as with other drugs known to inhibit prostaglandin synthesis, increased the incidence of dystocia, delayed parturition, and decreased pup survival.

Fenoprofen Breastfeeding Warnings

It is not known if fenoprofen is excreted into human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue fenoprofen, taking into account the importance of the drug to the mother.

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