Avapro

Generic Name: irbesartan ( ir be SAR tan)
Brand Names: Avapro

What is Avapro?

Avapro is in a group of drugs called angiotensin II receptor antagonists. It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. It works by decreasing the levels of certain chemicals in the body.

Avapro is used to treat high blood pressure. It is sometimes given together with other blood pressure medications.

Avapro is also used to treat kidney problems caused by type 2 (not insulin-dependent) diabetes.

Avapro may also be used for other purposes not listed in this medication guide.

Important information about Avapro

Do not use Avapro without telling your doctor if you are pregnant. Avapro may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. You should not use Avapro if you are allergic to irbesartan. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Avapro. Do not use potassium supplements or salt substitutes while you are taking Avapro, unless your doctor has told you to.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.

Keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Before taking Avapro

You should not use Avapro if you are allergic to irbesartan.

Before using Avapro, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease;
• liver disease;

• congestive heart failure; or

• if you are dehydrated.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Avapro may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Do not use Avapro without your doctor's consent if you are pregnant. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether Avapro passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Avapro?

Take Avapro exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

You may take Avapro with or without food.

To be sure Avapro is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.

Keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store Avapro at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include fast or slow heartbeat, dizziness, or feeling like you might pass out.

What should I avoid while taking Avapro?

Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Avapro. Do not use potassium supplements or salt substitutes while you are taking Avapro, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avapro side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• feeling like you might pass out;

• painful or difficult urination;

• chest pain, fast heart rate;

• swelling in your hands or feet.

Less serious side effects may include:

• runny or stuffy nose, sore throat, cough;

• muscle or joint pain;

• nausea, vomiting, stomach pain, heartburn, diarrhea;

• mild itching or skin rash;

• feeling anxious or nervous;

• headache, dizziness; or

• tired feeling.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Avapro?

Before taking Avapro, tell your doctor if you are using any of the following drugs:

• a diuretic (water pill);

• digoxin (digitalis, Lanoxin); or

• a blood thinner such as warfarin (Coumadin).

This list is not complete and there may be other drugs that can interact with Avapro. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about Avapro.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Avapro only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2008 Cerner Multum, Inc. Version: 3.05. Revision Date: 01/24/2008 10:20:20 AM.

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