I have been taking 150 mg of Wellbutrin for a month. My Dr wants me to go to 300 mg. Will I feel a lot better taking the 300mg? Has anybody gone from 150 to 300 mg of Wellbutrin. I feel good, my Doctor said I will feel great on 300mg.Want to get over depression, not wanting to do things, not social, etc. Any side effect issues. I tolerated the 150 well.
Wellbutrin: Raising dose from 150 to 300 mg?
Question posted by D C 2013 on 18 July 2014
Last updated on 24 May 2020 by Desiree85
15 Answers
Desiree85
25 May 2020
I’m on the same—150mg of Wellbutrin. Have been for about 3 months and don’t feel great—I feel just monotone. Although I feel more easily quick to anger—which is not me. I am wondering if I need to up my dosage? I would like to have more “umph” and actual want to get up and out of bed, more motivation to want to do more...
Tcbt
1 Dec 2018
My Dr put me on 150mg XL for a week and I was feeling much better, then he upped it to 300, I am on my 4th day & each day I feel exhausted all day, no energy. I called my pharmacist today & he said need to go back on 150’s until my body gets used to. But he said not to cut the 300’s in half. Getting new script Monday. I was so pleased that first week now I’m back in the dumps, but see light at end of tunnel!
eliruiz
23 April 2018
They’ll generally start you with 150mg, later upping you to the therapeutic level - usually 300 mg. I took 150 for a month and then went to 300. I have to say that this is a great adhd drug. Strange, lucid dreams hAve been my only negative side-effect, and I’m the type who almost never remembers a dream. I do these. Otherwise all good.
jevbrowser
24 April 2018
Does anyone know if there exists "ONE SINGLE WELLBUTRIN 200mg XL PILL" that is taken once per day? I know that there are 2 100mg pills that people sometimes take. But wondering about my questions specifically.
Any help would be appreciated.
Jev
cking5803
9 May 2018
I have been on 150mg for several years & my dr. just upped my dosage to 300mg a couple of weeks ago. I have filled my script & it came as a 300mg pill that I take once a day, so I would think it should be available as a once a day 200mg dosage pill also. Check with your pharmacist, they can tell you for sure.
Happiness4life
28 Jan 2018
I worked in the pharma industry. All of the generics cause really bad side effects from their fillers and amount of the active drug. PAR Pharma(I do not work for them) is a generic manufacture that I heard is bio equivalent to the brand Wellbutrin. I take 150mg with zero side effects. I have the PAR bupropion 300mg ready to increase to but I am nervous about the groggy side effects people have mentioned. I am already a tired person. I need energy not lethargy.
Inactive
24 April 2018
The most irritating side effect I experienced from taking the generic Wellbutrin manufactured by Par pharma was the carb cravings and increased appetite. So I switched to another generic instead. I tried several before I found the one I liked the most.
Inactive
23 Jan 2018
Hi I have been taking Wellbutrin since July on 150 mg. I look like I have Parkinson’s disease when I am at rest. Bc when I’m resting or sitting or thinking or getting nervous then I can’t stop jerking and twitching!! Can this be the drug? Also, now this week my Dr raised me to 300 mg and now my Immovane sleeping pill is not keeping me asleep longer than 4 hours?? Can this be the drug too? I have to increase the Immovane now to 1 1/2 pills. I think I feel better mentally on the Wellbutrin 300 mg bc I’m not caring as much and just accepting my situation of why I went on the antodepressants in the first place ... But this twitching has to stop!!! HELP!!
happy_tom
15 Dec 2017
Hi there, if you are feeling good at 150, I would not go up tp 300 because the side effects are likely to intensify. I made the error of increasing the dose and became very hostile, angry and irritable. Overall though, this drug works for me at 300, and I do have days when I like myself and view the world as a kind place
Seekingwellness2017
10 Aug 2017
I was prescribed Wellbutrin on Monday and was told by my pharmacist to take one a day for 3 days and then switch to the full dose of 2 a day. Should I be waiting longer to take 2? My doctor just prescribed it as a 2 a day and didn't give any instructions on starting with a smaller dose.
Deechancey13
15 June 2017
I too am wondering when I should increase my dosage. I have been on 150 mg Wellbutrin SR for two weeks now. It's suppose to be two a day but I started off with one in the morning to see how my body reacted. Insomnia the first few nights and I had taken my pill at 7am , I couldn't imagine if I took my second dose how long I'd be up. I am taking this Bc I have very little energy mostly do to not sleeping more than a few hours a night for past 3 years. My fiancé has severe ADHD , anxiety , and panic attacks as well as insomnia. So I'm up with him. And now recently my 3 year old wakes up twice a night also. So this helps me not feel tired when I only get a few hours of sleep and it has lifted my mood and makes me want to get off work he couch and be productive. However my side effects now are hand tremors and I feel like my body is shaky from the inside. I also have body twitches at night where it wakes me up...
I work in surgery so I can't have shaky hands. I want to eventually up my dose Bc I feel it wears off around 6pm but I'm scared to with these side effects and making them worse. So I guess my question also is when should I up my dose and how long between doses do you wait. It says 6-8hours to avoid risk of seizures ? Any advice is greatly appreciated !
Vintage Rose
28 Feb 2017
Yes, I was taking 150 Wellbutrin XL for over a year along with Lexapro 20mg.
Take Lexapro at night & Wellbutrin in am. Wellbutrin compliments a SSRI as they affect different chemical in brain.
Recently because my husband has been very ill, I started suffering more with depression, lack of motivation & just getting by. My dr. approved an increase to 300mg. I was afraid of going through some side effects however, I really smoothed through with taking Bonnine Sea Sickness Tablets that help with dizziness & upset stomach. I read a tip about this to help with transitions. I only noticed mild side effects for about 3 days. I immediately started to feel better! It has helped with motivation, emotions, better focus, etc. And, I'm noticing it is helping with appetite control which I so desperately needed. I have started a short walking program at the beach whereas, before I couldn't get off the couch or out of the house easily.
I'm so thankful the increase has helped me & I hear if it agrees with you, your depression gets better & better!
This is my experience with the increase & it has been a life saver for me & my caregiving for my husband. I hope anyone that goes to the increase has an improvement!! XO
cleo-pj
26 March 2018
That's awesome. Yes Wellubrutrin will compliment a SSRI. My new physician is fabulous. He put me on Lexapro 10mg and wellubrutrin 150mg. Have been taking both for past 3 weeks, though I feel both should be Increased. I dont really have any symptoms of either. Lyrica was started... I am having lots of drowsiness from that. I do have much faith both Wellbutrin and Lexapro will help with my depression and PTSD/anxiety disorder.
Inactive
2 Feb 2017
February 1, 2017:
In late August of 2016, I'd been just above suicidal for over 3 months; I was just barely functioning at work, and I'd completely shut down emotionally outside of work.
I couldn't advocate for myself in my "romantic" relationship (which was toxic). I'd been taking various psych meds for over 20 years at that point.
I began 150 mg Wellbutrin XL. I did experience some side effects, such as clenching my jaw and two other things that I can no longer recall.
After a week, I was doing much better, but still not as good as I'd hoped that I could. I followed my doctor's advice and waited the recommended three more weeks to have our appointment without increasing the dosage on my own. By the time the second appointment came around, the side effects had lessened a lot.
At the second appointment (4 weeks after beginning the 150 mg XL), my psychiatrist increased my dosage to 300 mg. While I did experience a slight resurgence in the side effects, they went away completely within 2 months.
I feel great now. I'm not sure what feeling better could possibly feel like. I'm now cheerful most of the time, yet I'm still able to feel sadness when appropriate, like when a guy told me he didn't want to date me anymore. The difference now is that I can cry for a day or two and then I'm honestly able to move on from those unpleasant feelings.
58andsucky
29 April 2017
Hi vibrant,
I feel your pain and I know what it feels to have all everything shut I cried at least 20 times. My doc said that I was resistant and clinical. I could go one but I won't!
Good luck and I will be thinking about you and we kindred friends:).
Trooper12
1 Feb 2017
This is the exact question I wanted to ask so I appreciate the responses even if most of them are 6 years old.
I just increased yesterday and I don't feel so much drowsy as "out of it". I have chllls and my extremities feel a little disconnected from my brain-if that makes any sense. I feel groggy and foggy.
I am wondering how soon this will subside because I am afraid to take my next 150 mg if it's going to elevate this bad feeling. With my doctor's permission I increased my dose because 200 mg a day was not working well anymore. So at this point I am going on faith that it will be ok.
Cody610
1 Jan 2018
Yeah it will, only lasts a few days and should subside. Just keep taking it and if in 2 weeks symptoms are still present have a talk with your doctor.
As far as going from 150mg of Wellbutrin to 300mg that absolutely isn't an issue at all. In fact most recommend doing so after a couple weeks. It made a big difference for my depression, 150mg helped a little but 300mg made me feel great, as in mood wise. Gives me motivation and what not. Sometimes I get dry mouth and minor muscle spasms but really nothing remotely serious or debilitating.
Hope this helped, good luck!
Victoria Stuart
3 June 2015
Yes. I take 150mg in the morning and 150MG in the afternoon and I feel much better than just taking one day.
58andsucky
26 April 2017
Thank you I appreciate your message and yes on 150 to 300. All in morning or am and pm? I take inpiramine 250 mg at night it makes me very tired. I liked the Wellbutrin with of 3 days of trying it felt great then the last week or so not so much. I live w my 42 year old son and his family and my grandson 4 yrs old he is the best. My son mental abuser it's tough in the rental market a 1000 plus for a one bed one bath. Thank you for listening!!
58andsucky
26 April 2017
One more thing I had side effects that lasted a little too long. I found myself talking in a conversation and then I would talk I would stutter then forget to add certain words when I sent an email. Dry mouth like crazy. That's all better it's the forgetting the words when I tried to send a simple email I have to read it a few times then send it. Thank you so much!!
Popular pete
2 Dec 2017
I was on Wellbutrin 300mg for about 10yrs.
This past summer I decided it was time to
wean myself off which I did. Felt great for
close to 4 weeks and suddenly crashed. It
was horrible! Went to doctor who started me
on Prozac first; Lexapro second. No good
and wasted at least six weeks. Now back on
generic Wellbutrin. Started at 150 XL; now
4 days on 300. Starting to feel like myself again. Lots of side effects last few weeks but
needed to do this! Unbelieveable experience!
twag121
13 Dec 2017
I've been taking bupropion xl for 7 days at 150 mg. Tomorrow I will start taking 300 mg. I'm still dealing with a lot of anxiety which is very debilitating. I was on Zoloft before this and it got to the point where it wasn't working, so bupropion xl was the next choice. I really want to be able to focus and take control of my life.
jevbrowser
17 April 2018
Regarding this entire thread: I've only been on 150mg per day for 5 days. My depression had gotten better already, but then i started .5mg of Klonopin today at my doctors direction. I think the Klonopin had a slight negative effect on the dopamine being produced by the Wellbutrin. So i want to go to 300mg per day of Wellbutrin to help my depression. I am ready to do it today, but my 150mg Wellbutrin pills are XL. Does that matter? Can i take those pills twice per day? Is that ok? Or do i need the SR pills (not exactly sure the difference)
jev
4N Substances
27 Aug 2014
Hi DC,
Sounds great so far! Wellbutrin is widely prescribed and generally well tolerated by patients, with few side effects. I think you'll experience increasingly positive results and wish you good luck. Keep us posted.
elizza
26 Aug 2014
Hey there! I started on 150 mg and after a few weeks went up to 300 mg. I honestly didn't experience any additional side effects. They only side effect I get ( which i had from the start) are little muscle jerks, but they aren't noticeable to others or bothersome to me. I feel pretty good on it! Sounds like you'll do great!
LaurieShay
18 July 2014
300 is the usual therapeutic level though dosage can go as high as 450mgs. your doctor is right and you should tolerate well since you did ok on 150mgs.
D C 2013
18 July 2014
Can I expect to feel even better taking 300mg. I don't feel as tired, more social and I have been doing more things than I usually have. I did have some insomnia at first but it got better after the first week. thank you
LaurieShay
18 July 2014
yes, you can expect to feel even better. You may experience a little jitteriness, but this too will pass.
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Further information
- Wellbutrin uses and safety info
- Wellbutrin prescribing info & package insert (for Health Professionals)
- Side effects of Wellbutrin (detailed)
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