Is Tramadol HCL an opiate?
- 23 Mar 2013 by bygrace721
- cymbalta, pain, hairy cell leukemia, fibromyalgia, tramadol, chronic pain, opiate
Recently prescribed Tramadol for Fibromyalgia pain. Also take Cymbalta. Reading up on Tramadol makes it sound like it is addictive and maybe should not be used with anti-depressants like Cymbalta.
II don't really feel any immediate reaction to taking it, but I have noticed after taking it only once every other day or so, I am very, very sleepy for at least 2 days after I take it.
23 Mar 2013
Tramadol is not an opiate but it works on the same receptors
Think of it this way. If you have a puzzle piece and it fits and then you have another piece that fits almost the same way
As with any drug it can be abused but that should not scare you from much needed pain relief
23 Mar 2013
Tramadol IS a synthetic opioid. It is considered an "Opioid Analgesic" and does work like some SNRI antidepressants, which can (very rarely!) lead to serotonin syndrome.
You are taking so little of Tramadol that I wouldn't be the least bit worried.
You may want to ask your doc about the drowsiness during the day, however.
23 Mar 2013
It is definitely not recommended to take these 2 drugs together. But it will depend on the dosage and when you take the 2 different meds.
I would contact your doctor, nurse or your pharmacy as soon as possible to double check when you are to take each drug and whether there needs to be any changes made.
Cymbalta has many drugs it should not be taken with and Tramadol is one of them.
If you happen to have or develop any of these side effects - confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremor, stomach cramp, nausea, vomiting, and diarrhea - get someone to take you to the hospital.
24 Mar 2013
Ive been using tramadol for over a year now. The dose you are on will not make feel the same as hydrocodone or oxycodone. At your dose, which isthe same I take, will gently remove your pain. Give it time to work before you give up. Yes, people become addicted because they abuse the drug. Take it only as directed and you should be just fine.
24 Mar 2013
Tramadol is a centrally acting synthetic analgesic used to treat moderate to moderately severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, motor neurone disease and fibromyalgia.
Unlike opioid analgesics, tramadol is not currently scheduled as a controlled substance by the U.S. Drug Enforcement Administration.
Structurally, tramadol closely resembles a stripped down version of codeine
Tramadol is a very weak μ-opioid receptor agonist, induces serotonin release, and inhibits the reuptake of norepinephrine.
The opioid agonistic effect of tramadol and its major metabolite(s) is almost exclusively mediated by such μ-opioid receptors. This further distinguishes tramadol from opioids in general (including morphine), which do not possess tramadol's degree of receptor subtype selectivity and which are much stronger opiate-receptor agonists. Similarly, the habituating properties of tramadol (such as they are) are arguably mainly due to μ-opioid agonism with contributions from serotonergic and noradrenergic effects.
Tramadol is used similarly to codeine, to treat moderate to severe pain. Pharmacologically, Tramadol is similar to levorphanol (albeit with much lower μ-agonism), both agents have SNRI activity.
Long-term use of high doses of Tramadol may be associated with physical dependence and a withdrawal syndrome. Tramadol causes typical opiate-like withdrawal symptoms as well as atypical withdrawal symptoms including seizures.
3 hours 10 minutes ago
It is a synthetic but considered an opioid. I take it at night with zanaflex, benadryl and magnesium. My husband takes his with his percoet his pain is so bad.
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