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Related terms: Carcinoma, Malignant Disease, Malignant Tumor

Beleodaq Approved for Aggressive non-Hodgkin Lymphoma

Posted 3 Jul 2014 by Drugs.com

THURSDAY, July 3, 2014 – Beleodaq (belinostat) has been approved by the U.S. Food and Drug Administration to treat peripheral T-Cell lymphoma (PTCL), a rare and aggressive form of non-Hodgkin lymphoma (cancer of the lymph nodes). Some 70,800 Americans will be diagnosed with non-Hodgkin lymphoma this year, of which up to 15 percent will be PTCL, according to U.S. National Cancer Institute estimates. Beleodaq is designed to inhibit immune cells called T-cells from becoming cancerous, the FDA explained Thursday in a news release. The drug is intended for people whose cancer has returned or who didn't respond to a prior therapy, the agency said. Beleodaq's safety and effectiveness were evaluated in clinical studies involving 129 people with PTCL. All were treated with the newly approved drug, and about 26 percent had their cancer disappear or shrink, the FDA said. The most common side ... Read more

Related support groups: Cancer, Lymphoma, Non-Hodgkin's Lymphoma, Peripheral T-cell Lymphoma

HIV Patients Less Likely to Get Cancer Treatment: Study

Posted 1 Jul 2014 by Drugs.com

TUESDAY, July 1, 2014 – While medications are helping HIV-positive people avoid developing full-blown AIDS indefinitely, a new study finds that cancer patients with HIV are up to four times less likely to be treated for their tumors. The research comes with caveats. It looked at just three states from 1996, when powerful HIV drugs first began changing the face of the disease, to 2010, when patients routinely took the medications. And the study doesn't explain why HIV-positive people with cancer receive less treatment or how this affected their lifespans. Still, "the main message is that these patients are not receiving appropriate cancer therapy," said study author Dr. Gita Suneja, an assistant professor of radiation oncology with the University of Utah. "There's a lack of awareness about the issue as a whole because any one physician will see few of these patients. It's something that ... Read more

Related support groups: Cancer, HIV Infection

FDA Medwatch Alert: Docetaxel: Drug Safety Communication - May Cause Symptoms of Alcohol Intoxication

Posted 24 Jun 2014 by Drugs.com

ISSUE: FDA is warning that the intravenous chemotherapy drug docetaxel contains ethanol, also known as alcohol, which may cause patients to experience intoxication or feel drunk during and after treatment. FDA is revising the labels of all docetaxel drug products to warn about this risk.  BACKGROUND: Docetaxel is a prescription chemotherapy drug used to treat different kinds of cancer, including cancers of the breast, prostate, stomach, head and neck cancers, and non-small-cell lung cancer.  RECOMMENDATION: Health care professionals should consider the alcohol content of docetaxel when prescribing or administering the drug to patients, particularly in those whom alcohol intake should be avoided or minimized and when using it in conjunction with other medications. Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these p ... Read more

Related support groups: Cancer, Taxotere, Docetaxel, Docefrez

When Is the Cost of Cancer 'Toxic'?

Posted 22 Jun 2014 by Drugs.com

FRIDAY, June 20, 2014 – A tool to assess "financial toxicity" for cancer patients – namely, the expense, anxiety and stress of illness-related costs – has been developed by University of Chicago Medical Center cancer specialists. Many cancer patients face exorbitant and unpredictable treatment costs often at a time when they're less able to work, the researchers point out. "Few physicians discuss this increasingly significant side effect with their patients," study author Dr. Jonas de Souza, a head-and-neck cancer specialist, said in a university news release. "Physicians aren't trained to do this. It makes them, as well as patients, feel uncomfortable. We aren't good at it." According to de Souza, "a thoughtful, concise tool that could help predict a patient's risk for financial toxicity might open the lines of communication." The team developed a brief questionnaire after ... Read more

Related support groups: Cancer

Childhood Cancer Survivors More Likely to Be Hospitalized: Study

Posted 15 Jun 2014 by Drugs.com

THURSDAY, June 12, 2014 – Childhood cancer survivors wind up in the hospital more often than other people, a new study finds. The researchers looked at nearly 1,500 people who were treated for childhood cancer between 1975 and 2005, and a "control" group of more than 7,700 people who never had cancer. All of the cancer survivors were at least five years past their diagnosis at the start of the study. Compared to the control group, childhood cancer survivors were 52 percent more likely to be hospitalized and had a 67 percent higher number of hospital admissions. The cancer survivors were also 35 percent more likely to have stayed longer every time they were hospitalized, the investigators found. More than 10 percent of people who survived central nervous system tumors, neuroblastoma (a cancer that develops from immature nerve cells) or bone tumors during childhood were hospitalized five ... Read more

Related support groups: Cancer

Cancer Survivors Face Mounting Costs of Continuing Medical Care: Study

Posted 12 Jun 2014 by Drugs.com

THURSDAY, June 12, 2014 – People who survive cancer are likely to face a lifelong drain on their finances as they pay for mounting medical expenses year after year, a new government report finds. According to the researchers from the U.S. Centers for Disease Control and Prevention, male and female cancer survivors incur annual medical costs that are almost two times greater than those of people who haven't had cancer. "Throughout their lifetime, they will still be going through treatments and checkups and long-term side effects and late effects that can come as a result of survival," explained study author Donatus Ekwueme, a senior health economist at the CDC's division of cancer prevention and control. Cancer survivors also face an increased risk of having another cancer, which means they have to undergo more regular screenings and tests than the average person, said Dr. Richard ... Read more

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Tumor-Targeting Agent Attaches to Cancer Cells: Study

Posted 11 Jun 2014 by Drugs.com

WEDNESDAY, June 11, 2014 – A new type of tumor-targeting agent may help detect and treat a wide variety of cancers, according to a new study. This new agent – dubbed the tumor-targeting alkylphosphocholine (APC) molecule – can travel throughout the body, even crossing the normally difficult-to-penetrate blood-brain barrier, and stick to cancer cells throughout its journey, researchers say. Because it attaches to cancer cells and not to healthy ones, it could potentially be used to mark cancer cells for imaging tests or be used to deliver radioactive medication directly to cancer cells. Animal studies and early human clinical trials indicate that the APC molecule can deliver a radioactive or fluorescent imaging label to cancer cells, as well as radioactive medicine that binds to and destroys the cells. APC enters the body in an intravenous solution and sticks to the membrane of cancer ... Read more

Related support groups: Cancer

Sophisticated Chest Scans May Raise Children's Lifetime Cancer Risk

Posted 9 Jun 2014 by Drugs.com

MONDAY, June 9, 2014 – Children who have imaging tests for heart problems have higher cancer risks over their lifetime, a new study says. These tests, which include cardiac catheterization and CT scans, are more complex than standard X-rays, and expose kids to higher doses of radiation than X-rays do, researchers at Duke University Medical Center explained. "There are definitely times when radiation is necessary, but it's important for parents to ask and compare in case you can avert potentially high-exposure procedures. Often, there are alternative or modified procedures with less radiation, or imaging may not actually be necessary," study author Dr. Kevin Hill, an assistant professor of pediatrics in the cardiology division at Duke, said in an American Heart Association news release. The study, published June 9 in the journal Circulation, involved 337 children under the age of 6. All ... Read more

Related support groups: Cancer

Cancer, Heart Disease Not Likely Killers of Those Over 100

Posted 4 Jun 2014 by Drugs.com

WEDNESDAY, June 4, 2014 – Pneumonia and frailty are more likely to be the cause of death among people aged 100 and older, rather than chronic conditions such as cancer or heart disease, new research shows. The findings are based on data on centenarian deaths in England between 2001 and 2010. Worldwide, the number of centenarians is expected to reach 3.2 million by 2050. According to a report from the U.S. Census Bureau, there were more than 53,000 people aged 100 or above in the United States in 2010, with the number slowly rising over time. The new study of British centenarians included almost 36,000 people, 87 percent of them women, with a median age of 101 at the time of death. The number of deaths for people age 100 or more in England rose by 56 percent over 10 years, from 2,823 in 2001 to 4,393 in 2010. According to the study, these very old individuals were most likely to die in ... Read more

Related support groups: Cancer, Heart Disease

Medicaid Patients Get Worse Cancer Care, Studies Contend

Posted 4 Jun 2014 by Drugs.com

WEDNESDAY, June 4, 2014 – Medicaid patients appear to receive worse cancer care than people who can afford private insurance, a trio of new studies says. Those covered by Medicaid, the federal health plan for low-income people, are less likely to have their cancer caught at an earlier, more treatable phase. Medicaid patients also are more likely to die from cancer than people with private insurance, researchers found. Many factors likely contribute to this, including the fact that Medicaid patients often aren't experienced in navigating the health care system, said Dr. Jyoti Patel, an oncologist at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University in Chicago. "Research has shown that we can screen more patients, but that they get dropped along the way to treatment. We don't give them full access into curative therapy," said Patel, who's also a spokeswoman for ... Read more

Related support groups: Cancer

Number of Cancer Survivors Should Grow to 19 Million in Next Decade: Report

Posted 2 Jun 2014 by Drugs.com

SUNDAY, June 1, 2014 – The number of cancer survivors in the United States will rise from the current 14.5 million to nearly 19 million by 2024, a new report predicts. Cancer rates have been falling for 10 years, but the number of cancer survivors is rising due to factors such as earlier detection and better treatments, the American Cancer Society said. "The growing number of cancer survivors in the U.S. makes it increasingly important to understand the unique medical and psychosocial needs of survivors," report author Carol DeSantis, an American Cancer Society epidemiologist, said in a cancer society news release. "Despite the fact that awareness of survivorship issues has increased, cancer survivors face numerous, important hurdles created by a fractured health care system, poor integration of survivorship care and financial and other barriers to quality care, particularly among the ... Read more

Related support groups: Cancer

Memory Problems After Chemo Linked to Brain Changes

Posted 27 May 2014 by Drugs.com

TUESDAY, May 27, 2014 – Breast cancer survivors who had chemotherapy show changes in brain activity during multitasking chores, according to a new Belgian study. These findings may partly explain the phenomenon dubbed "chemo brain." For years, people who've had chemotherapy have reported changes in thinking and memory, especially when doing more than one thing at once. "Before you can fix a problem, you need to know what the problem is. And this study demonstrates what the problem may be. It's a really good first step to understanding the what. Now we need to understand the why and how to fix it," said Dr. Courtney Vito, a breast surgeon and assistant clinical professor of surgical oncology at the City of Hope Comprehensive Cancer Center in Duarte, Calif. Vito was not involved in the current study, but reviewed the study's findings. In her experience, Vito said, women tend to be ... Read more

Related support groups: Cancer

Your Income Might Influence Your Risk for Certain Cancers

Posted 27 May 2014 by Drugs.com

TUESDAY, May 27, 2014 – Some cancers in the United States are tied to poverty, while others are more common among the wealthy, researchers report. In the poorest areas of the country, the incidence of cancer is generally lower than in richer regions, but deaths from cancers are higher, the study authors said. "Socioeconomic status is not something that appears on a medical record, so it is not really part of national cancer statistics, and this has skewed our thinking about cancer risk," said study co-author Kevin Henry, an assistant professor of epidemiology at Rutgers School of Public Health in New Jersey. Greater access to screening among the rich, and risky behaviors more common among the poor – such as smoking – may help explain the disparities, experts said. Kaposi sarcoma (a skin cancer common among AIDS patients) and cancers of the larynx, cervix, penis and liver occur more ... Read more

Related support groups: Cancer

Type of Kidney Disease May Dictate Cancer Risk

Posted 25 May 2014 by Drugs.com

THURSDAY, May 22, 2014 – Cancer risk for kidney transplant recipients may vary depending on the type of kidney disease they have, a new study finds. Patients with polycystic kidney disease (PKD), a genetic disorder, may be less likely to develop cancer than those with other types of kidney disease, but they still have a higher cancer risk than people in the general population, the researchers found. In polycystic kidney disease, cysts form in the kidneys, causing the kidneys to become enlarged. The condition affects nearly one in 1,000 people in the United States. The research team analyzed data from more than 10,000 Americans with polycystic kidney disease who received a kidney transplant and more than 107,000 transplant recipients with other kidney diseases. After adjusting for a number of factors, the researchers concluded that patients with polycystic kidney disease were 16 percent ... Read more

Related support groups: Cancer, Renal Cell Carcinoma, Chronic Kidney Disease, Polycystic Kidney Disease

Scientists Get Closer to the Stem Cells That May Drive Cancers

Posted 16 May 2014 by Drugs.com

THURSDAY, May 15, 2014 – Although the very concept of cancer stem cells has been controversial, new research provides proof that these distinct types of cells exist in humans. Using genetic tracking, researchers found that a gene mutation tied to cancer's development can be traced back to cancer stem cells. These cells are at the root of cancer and responsible for supporting the growth and progression of the disease, the scientists report. Cancer stem cells are able to replenish themselves and produce other types of cancer cells, just as healthy cells produce other normal cells, the study's British and European authors explained. "It's like having dandelions in your lawn. You can pull out as many as you want, but if you don't get the roots they'll come back," study first author Dr. Petter Woll, of the MRC Weatherall Institute for Molecular Medicine at the University of Oxford, said in ... Read more

Related support groups: Cancer

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