On Dec. 29th, 2011 I had what I thought would be my last period for awhile. It was heavy for about 5 days. I received the Depot Lupron shot on Jan 5th. After the 5 days of my period, I contintued to spot up until January 11th. Once I quit spotting, I thought I would not have my period again until my 6 shots of Depot Lupron were finished. However, on Jan. 20th, 2012 I started my period! It is very heavy like my other periods. I had 6 depot lupron shots in 2005 and 6 in 2008. During those rounds, I did not have my period after the first shot.