I took 2 capsules of Tylenol PM about 3 hours ago to help me fall asleep (I've used Tylenol PM quite a few times before). However, I switched body washes earlier this evening and I'm having an allergic reaction to it (itchy rash). My question is, how long do I have to wait until I can take Benadryl to clear up the rash? I don't want to overdoes on diphenhydramine as that is what's in the Tylenol Pm. Any help is appreciated!
9 Feb 2011
You need to wait at least 4 hours between doses. Each Tylenol PM contains 25mg diphenhydramine which is the same amount in an OTC Benendryl. If the Tylenol PM is not helping the itch, the Benedryl wont either. They are basically the same thing except Tylenol PM, of course, has the acetaminophen.
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