I started Epiduo in the middle of June and it has been almost 7 weeks now. I have seen absolutely no progress, it just keeps getting worse day by day. I have been doing everything I'm told and it just doesn't make sense. I am looking on a lot of people's reviews and for most of the people, their breakouts only lasted about 2-3 weeks. I don't know if it's just that my skin isn't reacting very well to the medication or if I'm doing something wrong or if I just haven't waited long enough. I just have one question though. Do I need to apply a pea sized amount to every affected area or like just a little from the pea sized amount to every affected area?