Interceptor Flavor Tabs for Cats (2.3 mg) (Canada)

(milbemycin oxime)

CATS

DIN 02141434 (2.3 mg), 02141426 (5.75 mg), 02141418 (11.5 mg), 02141396 (23.0 mg)

Interceptor Flavor Tabs for Cats (2.3 mg) Indications

INTERCEPTOR Flavor Tabs are recommended for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of parasitic infections due to adult hookworm (Ancylostoma tubaeforme) and adult roundworm (Toxocara cati) in cats two weeks of age or greater.

Dosage

Available in four sizes for convenient dosing of cats of various weights.

The minimum dosage level is 2 mg/kg of body weight. Cats weighing over 11.5 kg should receive the appropriate combination of INTERCEPTOR Flavor Tabs.

For heartworm prevention, administer INTERCEPTOR Flavor Tabs once per month on the same day.

Reminder stickers are provided for use on a calendar.

The initial dose must be given within a month after the first indication of mosquito activity and regular dosing should continue until at least one month after the end of the mosquito season. If the interval between doses exceeds 30 days, the efficacy of INTERCEPTOR may be reduced. If regular monthly treatment is delayed, it is essential to immediately recommence treatment at the recommended dosage rate. If treatment has been delayed beyond two months, the advice of a veterinarian should be sought.

For hookworm and roundworm, control will be obtained in conjunction with heartworm prevention, or by separate administration of INTERCEPTOR Flavor Tabs. Kittens should be treated every 2 weeks from 3 weeks of age to 3 months of age, then monthly until 6 months of age. In non-heartworm endemic areas, adult cats should be treated a minimum of 4 times per year, or as directed by the veterinarian.

Administration

INTERCEPTOR Flavor Tabs are highly palatable and may be given by hand. They may also be added to cat food or administered as a regular tablet.

The tablet(s) should be placed into the cat’s mouth on the back of the tongue, or can be hidden in food. The cat should be watched closely for several minutes following administration of the Flavor Tab to ensure that the entire dose has been swallowed. If it is suspected that any of the dose has been lost, dosing should be repeated.

Heartworm Disease In Cats:

Much of the damage due to heartworm disease in cats occurs before there are any outward signs of the disease, and these signs may be quite variable. Prevention of the disease is important.

The disease is caused by Dirofilaria immitis which lives in the right side of the heart and adjacent blood vessels. A cat not on preventive medication can be infected with several worms. The adult worms cause disease by damaging blood vessels in the lungs which obstructs normal blood flow. This can result in an increased workload on the heart which can cause heart failure. The adult worms can also migrate into tissues of the central nervous system such as the brain.

The disease is spread from animal to animal by any one of over 70 species of mosquitoes. Female adult heartworms discharge larval forms (microfilariae) into the bloodstream of a cat. The mosquito becomes infected by sucking up these microfilariae as it takes a blood meal from an infected cat; during the next two to three weeks these microfilariae grow and molt twice inside the mosquito to reach the infective larval stage which enters another cat as the mosquito feeds again. In the cat, it takes about seven to eight months for these larvae to grow, move to the heart, mate and start the cycle again.

Interceptor Flavor Tabs for Cats (2.3 mg) Cautions:

This product has not been tested in breeding cats, in pregnant queens or in heartworm positive cats.

Testing: Despite the fact that the sensitivity of the heartworm antigen tests is relatively low in cats, it is still considered good medical practice to test before administering chemoprophylaxis for the first time, if at least 8 months have passed since there was an opportunity for infection. The cat should be examined by a veterinarian prior to starting heartworm prevention medication.

Warnings:

Keep out of reach of children. If accidentally swallowed, call a physician.

Adverse Reactions

Although all adverse events are not reported, the following information is based on voluntary post-approval drug experience reporting. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using this data.

Emesis/vomiting, diarrhea and lethargy have been reported very rarely³ following INTERCEPTOR use in cats.

Signs most frequently seen following overdose include lethargy, ataxia, and muscle tremor in cats.

³Reported in less than 1 in 10,000 treatments.

Safety Studies

In safety studies INTERCEPTOR Flavor Tabs (milbemycin oxime) was tested and found to be safe in over 8 different breeds of cats and kittens, two weeks of age or greater. In clinical field studies, 310 cats completed treatment with milbemycin oxime. Milbemycin oxime was used safely in animals receiving frequently used veterinary products such as vaccines, anthelmintics, anesthetics, antibiotics, steroids, flea collars, shampoos and dips.

Safety studies were conducted in young cats and kittens beginning at two weeks of age. Doses of 1X, 3X and 5X demonstrated no drug-related effects. Tolerability studies at exaggerated doses of 10X also demonstrated no drug-related adverse effects in kittens and young adult cats.

Presentation:

INTERCEPTOR is available in four Flavor Tab sizes, formulated and package colour coded according to the weight range of the cat.

Available in the following package sizes: 6 INTERCEPTOR Flavor Tabs packaged 10 per display carton.

Storage Conditions

INTERCEPTOR Flavor Tabs should be stored at room temperature, 15 - 30°C.

Elanco Canada Limited, 1919 Minnesota Court, Suite 401, Mississauga, Ontario L5N 0C9

Date: April 2022

Interceptor, Flavor Tabs, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2022 Elanco or its affiliates

17May2022

CPN: 1231014.9