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Zytiga Side Effects

Generic name: abiraterone

Medically reviewed by Drugs.com. Last updated on May 12, 2024.

Note: This document provides detailed information about Zytiga Side Effects associated with abiraterone. Some dosage forms listed on this page may not apply specifically to the brand name Zytiga.

Applies to abiraterone: oral tablet.

Serious side effects of Zytiga

Along with its needed effects, abiraterone (the active ingredient contained in Zytiga) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking abiraterone:

More common

  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • blurred vision
  • bone pain or fracture
  • chest pain or discomfort
  • decreased urine
  • difficult, burning, or painful urination
  • dry mouth
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • feeling of warmth
  • frequent urge to urinate
  • headache
  • increased thirst
  • increased urge to urinate during the night
  • lightheadedness, dizziness, or fainting
  • loss of appetite
  • lower back or side pain
  • mood changes
  • muscle pain or cramps
  • nausea
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pain or swelling in the arms or legs without any injury
  • passing urine more often
  • pounding in the ears
  • rapid weight gain
  • redness of the face, neck, arms, and occasionally, upper chest
  • seizures
  • slow heartbeat
  • sudden sweating
  • swelling
  • swelling with pits or depressions on the skin
  • trouble breathing
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting
  • waking to urinate at night

Less common

  • arm, back, or jaw pain
  • chest tightness or heaviness
  • clay-colored stools
  • cool, sweaty skin
  • dark urine
  • decreased urine output
  • difficulty with breathing
  • dilated neck veins
  • extreme tiredness or weakness
  • fever
  • irregular breathing
  • itching skin or rash
  • light-colored stools
  • stomach pain or tenderness
  • sweating
  • weakness
  • weight gain
  • yellow eyes or skin

Rare

  • darkening of the skin
  • diarrhea
  • mental depression

Incidence not known

  • anxiety
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • cough
  • difficulty swallowing
  • general feeling of discomfort or illness
  • hives
  • increased hunger
  • irregular heartbeat, recurrent
  • muscle pain, spasms, stiffness, tenderness, wasting, or weakness
  • nightmares
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shakiness
  • slurred speech
  • stomach pain, continuing
  • thickening of bronchial secretions
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vomiting of blood

Other side effects of Zytiga

Some side effects of abiraterone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • belching
  • body aches or pain
  • difficulty with moving
  • ear congestion
  • heartburn
  • indigestion
  • joint pain
  • loss of voice
  • runny or stuffy nose
  • sneezing
  • sore throat
  • stomach discomfort or upset
  • swelling or stiffness of the joints

For healthcare professionals

Applies to abiraterone: oral tablet.

Endocrine

Hepatic

Cardiovascular

Musculoskeletal

Hematologic

Metabolic

Renal

Other

Respiratory

Genitourinary

Psychiatric

Gastrointestinal

Dermatologic

References

1. (2011) "Product Information. Zytiga (abiraterone)." Centocor Inc

2. (2018) "Product Information. Yonsa (abiraterone)." Sun Pharmaceutical Industries

Frequently asked questions

Further information

Zytiga side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.