Zypram Side Effects

Generic name: hydrocortisone / pramoxine topical

Note: This document contains side effect information about hydrocortisone / pramoxine topical. Some of the dosage forms listed on this page may not apply to the brand name Zypram.

Some side effects of Zypram may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to hydrocortisone / pramoxine topical: rectal cream, rectal foam, rectal kit, rectal lotion, topical cream, topical gel, topical lotion, topical ointment

Get emergency medical help if you have any of these signs of an allergic reaction while taking hydrocortisone / pramoxine topical: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

• blurred vision, or seeing halos around lights;

• uneven heartbeats;

• sleep problems (insomnia);

• ongoing headache;

• weight gain, puffiness in your face;

• increased thirst or urination, weight loss, unusual weakness;

• fever, sore throat, tired feeling;

• severe pain, burning, or irritation of treated skin;

• rectal bleeding;

• any new redness or swelling where the medicine was applied; or

• itching, oozing, or other signs of infection.

Less serious side effects of hydrocortisone / pramoxine topical may include:

• mild skin redness, burning, itching, dryness, or peeling;

• acne;

• changes in the color of treated skin;

• thinning of your skin;

• blistering skin; or

• stretch marks.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to hydrocortisone / pramoxine topical: rectal cream, rectal foam, rectal kit, rectal lotion, topical cream, topical gel, topical lotion, topical ointment

Dermatologic

Dermatologic side effects including burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria have been reported.

Hypersensitivity

Hypersensitivity side effects including allergic contact dermatitis have been reported.

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