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Hydrocortisone / pramoxine topical Pregnancy and Breastfeeding Warnings

Hydrocortisone / pramoxine topical is also known as: Analpram E, Analpram-HC, Enzone, Epifoam, HC Pram, HC Pramoxine, Hydropram, Novacort, Pramcort, Pramosone, Pramosone E, Procort, Proctofoam HC, Rectocort HC, Zone-A, Zone-A Forte, Zypram

Hydrocortisone / pramoxine topical Pregnancy Warnings

Hydrocortisone-pramoxine topical has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence that the more potent corticosteroids have been teratogenic after dermal application. Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. There are no controlled data in human pregnancy. Hydrocortisone-pramoxine topical should only be given during pregnancy when benefits outweigh risks. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Hydrocortisone / pramoxine topical Breastfeeding Warnings

It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a harmful effect on the infant. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman.

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