Xyntha Side Effects
Generic Name: antihemophilic factor
Note: This page contains side effects data for the generic drug antihemophilic factor. It is possible that some of the dosage forms included below may not apply to the brand name Xyntha.
For the Consumer
Applies to antihemophilic factor: intravenous powder for solution
As well as its needed effects, antihemophilic factor (the active ingredient contained in Xyntha) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking antihemophilic factor, check with your doctor immediately:More common
- Changes in facial skin color
- fast or irregular breathing
- puffiness or swelling of the eyelids or around the eyes
- sensation of burning, warmth, heat, numbness, tightness, or tingling
- skin rash, hives, or itching
- tightness in the chest
- troubled breathing
- unusual tiredness or weakness
- Bluish color of the fingernails, lips, skin, palms, or nail beds
- blurred vision
- chest pain or discomfort
- deep or fast breathing with dizziness
- difficult or labored breathing
- difficulty with swallowing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- noisy breathing
- numbness of the feet, hands, and around the mouth
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- slow or irregular heartbeat
- swelling of the face, throat, or tongue
- unusual tiredness or weakness
Some antihemophilic factor side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common
- Burning, stinging, or swelling at the place of injection
- dizziness or lightheadedness
- dry mouth or bad taste in the mouth
- lack or loss of strength
- redness of the face
- Change in taste
- loss of taste
- Abdominal or stomach pain
- feeling of warmth
- increased sweating
- muscle or bone pain
- redness of the eye
- redness of the face, neck, arms, and occasionally, upper chest
- redness of the skin
- trouble seeing
For Healthcare Professionals
Applies to antihemophilic factor: intravenous kit, intravenous powder for injection
Nervous system side effects have included headache, dizziness, somnolence, and asthenia.[Ref]
Respiratory side effects have included dyspnea and rhinitis.[Ref]
Musculoskeletal side effects have included arthralgia.[Ref]
Local side effects have included injection site pain.[Ref]
General side effects have included pyrexia and chills.[Ref]
Gastrointestinal side effects have included nausea, diarrhea, and vomiting.[Ref]
Dermatologic side effects have include pruritus, rash, and urticaria.[Ref]
Cardiovascular side effects have included hemorrhage, hypotension, and vasodilatation.[Ref]
1. "Product Information. Koate-HP (antihemophilic factor)." Bayer, West Haven, CT.
2. "Product Information. Helixate FS (antihemophilic factor)." CSL Behring, King of Prussia, PA.
3. "Product Information. Xyntha (antihemophilic factor)." Wyeth Laboratories, Philadelphia, PA.
4. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.
It is possible that some side effects of Xyntha may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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