Xerese Side Effects
Generic name: acyclovir / hydrocortisone topical
Note: This document contains side effect information about acyclovir / hydrocortisone topical. Some of the dosage forms listed on this page may not apply to the brand name Xerese.
Some side effects of Xerese may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to acyclovir / hydrocortisone topical: topical application cream
Along with its needed effects, acyclovir / hydrocortisone topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking acyclovir / hydrocortisone topical:Rare
- Burning, itching, redness, skin rash, swelling, or soreness at the application site
- change in skin color at the application site
- dryness or flaking of the skin
- flushing or redness of the skin
- unusually warm skin
- Blistering, burning, or crusting of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to acyclovir / hydrocortisone topical: topical cream
During clinical trials, most side effects were local and occurred around the application site.
Local side effects have been reported most commonly and have included local skin reactions (less than 1%). Local skin reactions in the area of the application site have included drying or flaking of the skin, burning or tingling after application, erythema, pigmentation changes, and application site reaction (including signs and symptoms of inflammation). A high and cumulative irritation potential under occlusive and semiocclusive conditions was reported during a 21 day cumulative irritation study.
Hypersensitivity side effects have included contact allergy, sensitization to hydrocortisone, and possible sensitization to the drug's base.
During a photosafety study, one subject developed a contact allergy to propylene glycol (one of the inactive ingredients of the cream base).
Dermatologic side effects have included contact dermatitis.
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