Xerese Side Effects
Generic Name: acyclovir / hydrocortisone topical
Note: This page contains side effects data for the generic drug acyclovir / hydrocortisone topical. It is possible that some of the dosage forms included below may not apply to the brand name Xerese.
It is possible that some side effects of Xerese may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to acyclovir / hydrocortisone topical: topical application cream
As well as its needed effects, acyclovir / hydrocortisone topical may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking acyclovir / hydrocortisone topical, check with your doctor immediately:Rare
- Burning, itching, redness, rash, swelling, soreness, or tingling at the application site
- change in skin color at the application site
- dryness or flaking of the skin
- flushing or redness of the skin
- unusually warm skin
- Blistering, burning, or crusting of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to acyclovir / hydrocortisone topical: topical cream
During clinical trials, most side effects were local skin reactions and occurred around the application site.[Ref]
Uncommon (0.1% to 1%): Local skin reactions in application site area (including drying or flaking of skin, burning or tingling after application, erythema, pigmentation changes, application site reaction [including signs/symptoms of inflammation])
Frequency not reported: High and cumulative irritation potential[Ref]
A high and cumulative irritation potential under occlusive and semiocclusive conditions was reported during a 21-day cumulative irritation trial.[Ref]
Frequency not reported: Contact allergy, sensitization to hydrocortisone, possible sensitization to drug's base[Ref]
During a photosafety study, one subject developed a contact allergy to propylene glycol (one of the inactive ingredients of the cream base).[Ref]
Frequency not reported: Contact dermatitis[Ref]
1. "Product Information. Xerese (acyclovir-hydrocortisone topical)." Meda Pharmaceuticals, Somerset, NJ.
More about Xerese (acyclovir / hydrocortisone topical)
- Other brands: Lipsovir
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