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Wilate Side Effects

Generic Name: antihemophilic factor / von willebrand factor

Note: This page contains side effects data for the generic drug antihemophilic factor / von willebrand factor. It is possible that some of the dosage forms included below may not apply to the brand name Wilate.

For the Consumer

Applies to antihemophilic factor / von willebrand factor: intravenous powder for solution

As well as its needed effects, antihemophilic factor / von willebrand factor may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking antihemophilic factor / von willebrand factor, check with your doctor or nurse immediately:

More common:
  • Difficulty with breathing or swallowing
  • dizziness
  • fast heartbeat
  • fever
  • hives or welts
  • itching
  • nausea
  • reddening of the skin, especially around the ears
  • shortness of breath
  • skin rash
  • swelling of the face, throat, or tongue
  • unusual tiredness or weakness
Incidence not known:
  • Cough
  • tightness in the chest
  • vomiting
  • wheezing

For Healthcare Professionals

Applies to antihemophilic factor / von willebrand factor: intravenous powder for injection

General

The most serious side effects were anaphylaxis/hypersensitivity reactions.[Ref]

Immunologic

Common (1% to 10%): Allergy, infection, hypersensitivity
Uncommon (0.1% to 1%): Factor VIII inhibition
Very rare (less than 0.01%): Von Willebrand factor inhibition, anaphylactic shock
Frequency not reported: Allergic-anaphylactic reactions, sepsis[Ref]

Other

Very common (10% or more): Pain (up to 17.5%)
Common (1% to 10%): Fever, surgery, facial edema, chest pain, peripheral edema, rigors
Frequency not reported: Chills, pseudothrombocytopenia, postoperative pain
Postmarketing reports: Fatigue, malaise[Ref]

Gastrointestinal

Very common (10% or more): Nausea (up to 23.8%), constipation (11.1%)
Common (1% to 10%): Gastrointestinal bleeding, abdominal pain, vomiting
Frequency not reported: Postoperative nausea[Ref]

Hematologic

Common (1% to 10%): Groin bleed, ear bleed, shoulder bleed, anemia/hemoglobin decreased, thromboembolic event
Frequency not reported: Hemorrhage, hematocrit decreased, postoperative hemorrhage, postoperative wound bleeding
Postmarketing reports: Hemolysis[Ref]

Nervous system

Common (1% to 10%): Cerebral hemorrhage/subdural hematoma, dizziness, headache, dysgeusia, somnolence
Frequency not reported: Headache, paresthesia, drowsiness[Ref]

Respiratory

Common (1% to 10%): Epistaxis, hemoptysis, pulmonary embolus, sore throat
Frequency not reported: Respiratory distress
Postmarketing reports: Dyspnea, cough, sneezing, throat irritation[Ref]

Dermatologic

Common (1% to 10%): Sweating increased, pruritus, rash, urticaria[Ref]

Genitourinary

Common (1% to 10%): Menorrhagia, hematuria, urinary retention, urinary tract infection[Ref]

Hepatic

Common (1% to 10%): ALT increased, liver function test abnormal[Ref]

Musculoskeletal

Common (1% to 10%): Back pain, muscle and joint stiffness
Frequency not reported: Extremity pain
Postmarketing reports: Joint pain[Ref]

Cardiovascular

Common (1% to 10%): Thrombophlebitis
Frequency not reported: Orthostatic hypotension, phlebitis, vasodilation, bradycardia, palpitations[Ref]

Local

Common (1% to 10%): Infusion site erythema or rash or pain
Frequency not reported: Injection site bleeding
Postmarketing reports: Infusion site pain[Ref]

Psychiatric

Common (1% to 10%): Insomnia[Ref]

Ocular

Frequency not reported: Blurred vision[Ref]

Renal

Frequency not reported: Pyelonephritis[Ref]

Metabolic

Postmarketing reports: Hypervolemia[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation, Los Angeles, CA.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

4. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.

5. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA, Centreville, VA.

It is possible that some side effects of Wilate may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about Wilate (antihemophilic factor / von willebrand factor)

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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