Valchlor Side Effects

Generic Name: mechlorethamine topical

Note: This document contains side effect information about mechlorethamine topical. Some of the dosage forms listed on this page may not apply to the brand name Valchlor.

Some side effects of Valchlor may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to mechlorethamine topical: topical application gel/jelly

Along with its needed effects, mechlorethamine topical (the active ingredient contained in Valchlor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mechlorethamine topical:

More common
  • Blistering, crusting, irritation, itching, or reddening of the skin
  • cracked, dry, scaly skin
  • pain, swelling, tenderness, or warmth on the skin

Some side effects of mechlorethamine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Darkening of the skin

For Healthcare Professionals

Applies to mechlorethamine topical: topical gel

Dermatologic

Very common (10% or more): Dermatitis (56%), pruritus (20%), bacterial skin infection (11%)
Common (1% to 10%): Skin ulceration or blistering (6%), skin hyperpigmentation (5%)

Hematologic

Very common (10% or more): Reductions in hemoglobin, neutrophil count, or platelet count (13%)

Oncologic

Common (1% to 10%): Non-melanoma skin cancer (4%)

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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