Valchlor Side Effects
Generic Name: mechlorethamine topical
Note: This page contains side effects data for the generic drug mechlorethamine topical. It is possible that some of the dosage forms included below may not apply to the brand name Valchlor.
It is possible that some side effects of Valchlor may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to mechlorethamine topical: topical application gel/jelly
As well as its needed effects, mechlorethamine topical (the active ingredient contained in Valchlor) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking mechlorethamine topical, check with your doctor immediately:More common
- Blistering, crusting, irritation, itching, or reddening of the skin
- cracked, dry, scaly skin
- pain, swelling, tenderness, or warmth on the skin
Some mechlorethamine topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Less common
- Darkening of the skin
For Healthcare Professionals
Applies to mechlorethamine topical: topical gel
Very common (10% or more): Dermatitis (56%), pruritus (20%), bacterial skin infection (11%)
Common (1% to 10%): Skin ulceration or blistering (6%), skin hyperpigmentation (5%)[Ref]
Very common (10% or more): Reductions in hemoglobin, neutrophil count, or platelet count (13%)[Ref]
Common (1% to 10%): Non-melanoma skin cancer (4%)[Ref]
1. "Product Information. Valchlor (mechlorethamine topical)." Ceptaris Therapeutics, Malvern, PA.
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