Mechlorethamine topical Pregnancy and Breastfeeding Warnings

Mechlorethamine topical is also known as: Valchlor

Mechlorethamine topical Pregnancy Warnings

Mechlorethamine was teratogenic in animals after a single subcutaneous administration. Mechlorethamine can cause fetal harm when administered to a pregnant woman. There are case reports of children born with malformations in pregnant women systemically administered mechlorethamine. FDA pregnancy category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use of mechlorethamine topical is not recommended. If this drug is used during pregnancy or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to a fetus. FDA pregnancy category: D

Mechlorethamine topical Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Data not available The effects in the nursing infant are unknown.

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