Twinrix Side Effects

Generic Name: hepatitis a adult vaccine / hepatitis b adult vaccine

Note: This page contains side effects data for the generic drug hepatitis a adult vaccine / hepatitis b adult vaccine. It is possible that some of the dosage forms included below may not apply to the brand name Twinrix.

It is possible that some side effects of Twinrix may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to hepatitis a adult vaccine / hepatitis b adult vaccine: intramuscular suspension

Get emergency medical help if you have any of these signs of an allergic reaction while taking hepatitis a adult vaccine / hepatitis b adult vaccine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shot caused any side effects.

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.

Becoming infected with hepatitis is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

You may feel faint after receiving this vaccine. Some people have had seizure like reactions after receiving this vaccine. Your doctor may want you to remain under observation during the first 15 minutes after the injection.

Call your doctor at once if you have:

  • numbness, tingling, or burning pain;

  • red or blistering skin rash with burning or tingly feeling;

  • easy bruising or bleeding (nosebleeds, bleeding gums); or

  • unexplained muscle pain, tenderness, or weakness.

Common side effects include:

  • redness, tenderness, or a hard lump where the shot was given;

  • headache; or

  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to hepatitis a adult vaccine / hepatitis b adult vaccine: intramuscular suspension

General

Hepatitis A-hepatitis B vaccine is generally well-tolerated. Most side effects were mild, self-limiting, and of short duration (less than 48 hours).

Local

Local side effects have included soreness, redness, swelling, induration, pruritus, and ecchymosis at the injection site.

Other

Other side effects have included headache, fatigue, fever, sweating, weakness, flushing, influenza-like symptoms, tingling, tinnitus, and earache.

Cardiovascular

Cardiovascular side effects have included syncope, hypotension, tachycardia, and palpitations.

Dermatologic

Dermatologic side effects have included rash, urticaria, petechiae, erythema, hyperhidrosis, angioedema, eczema, herpes zoster, erythema nodosum, and alopecia.

Gastrointestinal

Gastrointestinal side effects have included diarrhea, nausea, vomiting, abdominal pain, anorexia, constipation, dysgeusia, and dyspepsia.

Hematologic

Hematologic side effects have included lymphadenopathy and thrombocytopenia.

Hepatic

Hepatic side effects have included jaundice, hepatitis, and abnormal liver function tests.

Hypersensitivity

Hypersensitivity reactions have included anaphylaxis, anaphylactoid reactions, erythema multiforme, Stevens-Johnson syndrome, angioedema, arthritis, and serum-sickness-like syndrome (arthralgia, arthritis, fever, urticaria, erythema multiforme, ecchymoses, and erythema nodosum).

Musculoskeletal

Musculoskeletal side effects have included arthralgia, myalgia, back pain, and creatine phosphokinase elevations.

Nervous system

Nervous system side effects have included migraine, paresthesia, vertigo, somnolence, insomnia, irritability, agitation, dizziness, hypertonic episode, convulsions, paresis, encephalopathy, neuropathy, myelitis, Guillain-Barre syndrome, multiple sclerosis, Bell's palsy, and transverse myelitis.

Ocular

Ocular side effects have included photophobia, optic neuritis, conjunctivitis, keratitis, and visual disturbances.

Respiratory

Respiratory side effects have included upper respiratory tract infections, dyspnea, bronchospasm, and asthma-like symptoms.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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