RespiGam Side Effects

Please note - some side effects for RespiGam may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of RespiGam - for the Consumer

RespiGam

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using RespiGam:

Fever; irritation at injection site; vomiting; wheezing.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breathing problems; decrease in amount of urine; drowsiness; fever; muscle rigidity; nausea; painful eye movements; sensitivity to sunlight; severe headache; vomiting.

Side Effects by Body System

Renal

Renal side effects associated with sucrose-containing IGIV infusion have included increased serum creatinine, increased BUN level, oliguria, anuria, acute renal failure, acute tubular necrosis, proximal tubular nephropathy, and osmotic nephrosis.

Other

Other side effects has included fever/pyrexia (6%) and overdose effect (1%). Pallor, cold/clammy skin, gagging, and fluid overload have been reported rarely.

Other side effects associated with other IGIV derivatives have included flushing. This effect is often related to the rate of infusion.

Respiratory

Respiratory side effects have included respiratory distress (2%), wheezing (2%), rales (1%), tachypnea (1%), and hypoxia/hypoxemia (1%). Cyanosis, cough, and rhinorrhea have been reported rarely.

Respiratory side effects associated with other IGIV derivatives have included dyspnea. This effect is often related to the rate of infusion.

Gastrointestinal

Gastrointestinal side effects have included vomiting (2%), diarrhea (1%), and gastroenteritis (1%).

Gastrointestinal side effects associated with other IGIV derivatives have included abdominal cramps. This effect is often related to the rate of infusion.

Cardiovascular

Cardiovascular side effects reported in 1% of patients have included fluid overload, tachycardia, increased pulse rate, and hypertension. Edema, hypotension, and heart murmur have been reported rarely.

Cardiovascular side effects associated with other IGIV derivatives have included blood pressure changes, palpitations, and chest tightness. These effects are usually related to the rate of infusion.

The CARDIAC study reported an increase in frequency of cardiac surgery in children with left and right shunts. All enrollees (n=429) had preexisting congenital heart disease of less than 48 months duration at time of enrollment. The study also reported a greater frequency of severe and life-threatening side effects associated with the cardiac surgery.

Dermatologic

Dermatologic side effects have included rash (1%). Eczema has been reported rarely.

Dermatologic side effects associated with other IGIV derivatives have included pruritus. This effect is usually related to the rate of infusion.

Local

Local side effects have included inflammation at injection site.

Nervous system

Nervous system side effects have rarely included sleepiness.

Nervous system side effects associated with other IGIV derivatives have included dizziness and anxiety. These effects are often related to the rate of infusion.

Ocular

Ocular side effects have rarely included conjunctival hemorrhage.

Musculoskeletal

Musculoskeletal side effects associated with other IGIV derivatives have included myalgia and arthralgia. These effects are often related to the rate of infusion.

Hypersensitivity

Hypersensitivity side effects, including anaphylactic reactions, have been associated with other IGIV derivatives.

Immunologic

Aseptic meningitis syndrome has been associated with high doses (2 g/kg) of IGIV.

Aseptic meningitis of unknown etiology has been reported in three pediatric patients during RSV-IGIV therapy in the PREVENT trial. Subsequent findings reported one child to have a presumptive diagnosis of enteroviral infection, and another child to have an unconfirmed diagnosis of Herpes simplex meningitis related to treatment with acyclovir. The third child developed fever, vomiting, and malaise associated with 21 cells per mm3 in the cerebrospinal fluid.

Immunologic side effects associated with other IGIV derivatives have rarely included aseptic meningitis syndrome.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.