Poly Hist DHC Side Effects
Generic name: dihydrocodeine / phenylephrine / pyrilamine
Note: This document contains side effect information about dihydrocodeine / phenylephrine / pyrilamine. Some dosage forms listed on this page may not apply to the brand name Poly Hist DHC.
Applies to dihydrocodeine / phenylephrine / pyrilamine: oral liquid.
You should not use this medicine if you have severe liver disease, inflammatory bowel disease, severe constipation, a blockage in your stomach or intestines, severe colitis or toxic megacolon, if you have a colostomy or ileostomy, if you are unable to urinate, if you have been sick with diarrhea, if you recently drank large amounts of alcohol, or if you have a head injury or brain tumor.
Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or a thyroid disorder.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Get emergency medical help if you have any of these signs of an allergic reaction while taking dihydrocodeine / phenylephrine / pyrilamine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using dihydrocodeine, phenylephrine, and pyrilamine and call your doctor at once if you have a serious side effect such as:
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confusion, mood changes, hallucinations, unusual thoughts or behavior;
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severe dizziness or drowsiness, feeling like you might pass out;
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severe nervousness, fast or uneven heart rate, tremor, seizure (convulsions);
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severe headache;
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severe stomach cramps or constipation;
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weak or shallow breathing;
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urinating less than usual or not at all;
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easy bruising or bleeding, unusual weakness; or
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dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain).
Less serious side effects of dihydrocodeine / phenylephrine / pyrilamine may include:
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dizziness, drowsiness, tired feeling;
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dry mouth, nose, or throat;
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blurred vision;
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increased sweating;
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headache, increased sweating, feeling anxious;
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diarrhea, upset stomach, nausea, vomiting, constipation; or
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sleep problems (insomnia);
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
More about Poly Hist DHC (dihydrocodeine / phenylephrine / pyrilamine)
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
