Pirbuterol Side Effects

It is possible that some side effects of pirbuterol may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to pirbuterol: inhalation aerosol powder

As well as its needed effects, pirbuterol may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking pirbuterol, check with your doctor immediately:

More common
  • Shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet
Less common
  • Fast, pounding, or irregular heartbeat or pulse
Rare
  • Blurred vision
  • bruising
  • chest pain
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • fainting
  • feeling of warmth
  • numbness in the arms or legs
  • redness of the face, neck, arms, and occasionally, upper chest
  • sweating
  • swelling
  • unusual tiredness or weakness

If any of the following symptoms of overdose occur while taking pirbuterol, get emergency help immediately:

Symptoms of overdose
  • Arm, back, or jaw pain
  • chest tightness or heaviness
  • confusion
  • convulsions
  • decreased urine
  • dry mouth
  • general feeling of discomfort or illness
  • headache
  • increased thirst
  • loss of appetite
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pounding in the ears
  • shortness of breath
  • sleeplessness
  • slow or fast heartbeat
  • trouble sleeping
  • unable to sleep

Some pirbuterol side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common
  • Cough
  • dizziness
Rare
  • Abdominal or stomach cramps
  • anxiety
  • bad, unusual, or unpleasant (after) taste
  • change in taste
  • depression
  • hair loss
  • increase in body movements
  • itching skin
  • redness, swelling, or soreness of the tongue
  • swelling or inflammation of the mouth
  • thinning of the hair
  • weakness
  • weight gain
  • weight loss

For Healthcare Professionals

Applies to pirbuterol: inhalation aerosol

Cardiovascular

Cardiovascular side effects have included palpitations and peripheral vasodilation, commonly resulting in reflex tachycardia. Blood pressure may increase or decrease. Higher doses may rarely aggravate angina, myocardial ischemia, or cause atrial or ventricular arrhythmias.

Although most studies have not revealed a significant effect of pirbuterol on blood pressure or heart rate, anecdotally significant increases have been noted. Aggravation of angina may be due to tachycardia produced by pirbuterol. Supraventricular premature beats and ventricular tachycardia have also been reported. Higher doses of pirbuterol should be used with caution in patients with cardiac disease, arrhythmias, or hypertension. All of these effects are dose-related and lower doses may be tolerated.

Musculoskeletal

Musculoskeletal side effects have included tremors, especially at higher doses.

Gastrointestinal

Gastrointestinal side effects have included nausea, dry mouth, and diarrhea.

Metabolic

Metabolic side effects have included hypokalemia and, less commonly, hyperglycemia.

Nervous system

Nervous system side effects have included nervousness, dizziness, insomnia, and headache.

Respiratory

Respiratory side effects have included cough. Rare instances of paradoxical bronchoconstriction have been associated with the use of pirbuterol.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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