MoviPrep Side Effects

Generic name: polyethylene glycol 3350 with electrolytes

Note: This document contains side effect information about polyethylene glycol 3350 with electrolytes. Some of the dosage forms listed on this page may not apply to the brand name MoviPrep.

Some side effects of MoviPrep may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to polyethylene glycol 3350 with electrolytes: oral kit, oral powder for reconstitution

Get emergency medical help if you have any of these signs of an allergic reaction while taking polyethylene glycol 3350 with electrolytes (the active ingredient contained in MoviPrep) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

If you have any of these side effects, you may need to drink the medication more slowly, or stop using it for a short time. Call your doctor for instructions if you have:

• severe stomach pain or bloating;

• no bowel movement within 2 hours after use; or

• gagging, choking, or vomiting.

Common side effects may include:

• mild stomach cramps, gas, or bloating;

• rectal pain or irritation;

• nausea; or

• passing gas.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to polyethylene glycol 3350 with electrolytes: oral kit, oral powder for reconstitution

Gastrointestinal

Mallory-Weiss tears are quite rare. In one study it occurred in only 0.06% of over 3,000 patients.

Complete rectal prolapse was reported in a 71-year-old who had been given 4 L of PEG-ELS. The patient was observed for 2 days and had no recurrence of the prolapse.

Gastrointestinal side effects have included nausea, vomiting, gas, bloating, complaints of bad taste, anal irritation, and abdominal discomfort. A small percentage of patients who received PEG-ELS have reportedly experienced Mallory-Weiss tears of the esophagus and esophageal perforation. In addition, at least one case of rectal prolapse has been reported.

Cardiovascular

Cardiac arrhythmias, especially increased ventricular ectopy, have been associated with PEG-ELS use.

Cardiovascular side effects have included arrhythmias.

Hypersensitivity

Hypersensitivity side effects have rarely included anaphylaxis. Rash, urticaria, lip and facial swelling, dyspnea, chest tightness, and throat tightness have been reported during postmarketing experience.

A 70-year-old male developed shortness of breath, wheezing, skin flushing, and lowered blood pressure after drinking a second glass of PEG-ELS.

Dermatologic

Dermatologic side effects have rarely included urticaria.

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