Methylergonovine Side Effects

Some side effects of methylergonovine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to methylergonovine: injectable solution, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking methylergonovine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• pain, swelling, warmth, or redness under your skin;

• seizure (convulsions);

• feeling like you might pass out;

• pounding heartbeats or fluttering in your chest;

• slow heart rate, trouble breathing;

• blood in your urine;

• severe weakness, muscle cramps, confusion, slurred speech, fainting;

• hallucinations;

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

• sudden numbness or weakness, especially on one side of the body;

• sudden severe headache, confusion, problems with vision, speech, or balance;

• pain, swelling, warmth, or redness in one or both legs; or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects of methylergonovine may include:

• nausea, mild stomach pain or vomiting, diarrhea;

• increased sweating, mild skin rash;

• leg cramps;

• mild headache, dizziness;

• ringing in your ears;

• stuffy nose; or

• unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to methylergonovine: injectable solution, oral tablet

Cardiovascular

Cardiovascular side effects have included palpitations, hypertension, hypotension, acute myocardial infarction, transient chest pains, arterial spasm (coronary and peripheral), bradycardia, and tachycardia. Postmarketing reports have included ventricular fibrillation, ventricular tachycardia, angina pectoris and atrioventricular block.

Hematologic

Hematologic side effects have included thrombophlebitis.

Metabolic

Metabolic side effects have included water intoxication.

Nervous system

Nervous system side effects have included tinnitus, hallucinations and dizziness. Postmarketing reports have included cerebrovascular accident and paraesthesia.

Gastrointestinal

Gastrointestinal side effects have included diarrhea, foul taste, nausea and vomiting.

Dermatologic

Dermatologic side effects have included diaphoresis and rash.

Genitourinary

Genitourinary side effects have included hematuria.

Respiratory

Respiratory side effects have included dyspnea and nasal congestion.

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