Mesoridazine Side Effects

Brand Names: Serentil

Please note - some side effects for Mesoridazine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Cardiovascular

Drugs with the potential to prolong the QTc interval have been associated with torsades de pointes-type arrhythmias and sudden death.

Cardiovascular side effects including hypotension and tachycardia have been reported. Mesoridazine has also been reported to prolong the QTc interval in a dose related manner.

Nervous system

Central nervous system side effects including drowsiness, Parkinson's syndrome, dizziness, weakness, tremor, restlessness, ataxia, dystonia, rigidity, slurring, akathisia, and motoric reactions (opisthotonos) have been reported. Autonomic nervous system effects including dry mouth, nausea and vomiting, fainting, stuffy nose, photophobia, constipation, and blurred vision have also been reported.

Adverse effects including rigidity and motoric effects tend to occur later in therapy.

Genitourinary

Genitourinary side effects including inhibition of ejaculation, impotence, enuresis, incontinence and priapism have been reported.

Dermatologic

Dermatologic side effects including itching, rash, hypertrophic papillae of the tongue, and angioneurotic edema have been reported.

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