Magnevist Side Effects

Generic name: gadopentetate dimeglumine

Medically reviewed by Drugs.com. Last updated on Oct 15, 2023.

Note: This document contains side effect information about gadopentetate dimeglumine. Some dosage forms listed on this page may not apply to the brand name Magnevist.

Applies to gadopentetate dimeglumine: injectable solution.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some side effects of gadopentetate dimeglumine (the active ingredient contained in Magnevist) may occur up to several days after injection.

Gadopentetate dimeglumine can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

• burning, itching, swelling, scaling, and tightening or hardening of your skin;

• muscle weakness;

• joint stiffness in your arms, hands, legs, or feet;

• deep bone pain in your ribs or your hips;

• trouble moving; or

• skin redness or discoloration.

Also call your doctor at once if you have:

• kidney problems--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or

• swelling, bruising, redness, itching, burning, or skin changes where the injection was given.

Common side effects may include:

• headache, dizziness;

• nausea;

• cold feeling, warmth, pain, or burning where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to gadopentetate dimeglumine: injectable solution.

Cardiovascular

Cardiovascular side effects have included hypotension, hypertension, arrhythmia, tachycardia, syncope, vasodilation, pallor, nonspecific ECG changes, angina pectoris, death related to myocardial infarction, phlebitis, thrombophlebitis, deep venous thrombophlebitis, and compartment syndrome requiring surgery.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included gastrointestinal distress, stomach pain, increased salivation, abdominal pain, vomiting, constipation, thirst, anorexia, dry mouth, and diarrhea.^[Ref]

Nervous system

Nervous system side effects have included agitation, anxiety, migraine, nystagmus, drowsiness, stupor, paresthesia, and convulsions.^[Ref]

Ocular

Ocular side effects have included diplopia, conjunctivitis, visual field defect, lacrimation disorder, eye irritation, and eye pain.^[Ref]

Respiratory

Respiratory side effects have included throat irritation, rhinorrhea, sneezing, dyspnea, wheezing, laryngismus, cough, and respiratory complaints.^[Ref]

Dermatologic

Dermatologic side effects have included rash, sweating, pruritus, urticaria, facial edema, erythema multiforme, epidural necrolysis, and pustules.^[Ref]

Local

Local side effects have included pain, localized warmth, and burning sensation at the injection site.^[Ref]

Hypersensitivity

Hypersensitivity side effects have included substernal chest pain, back pain, fever, weakness, generalized coldness, generalized warmth, localized edema, tiredness, chest tightness, trembling, shivering, tension in the extremities, regional lymphangitis, pelvis pain, and anaphylactoid reactions.^[Ref]

Other

Other side effects have included tinnitus and taste abnormalities.^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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